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ClinicalTrials.gov public records Last synced Oct 30, 2026, 6:55 AM EDT

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Showing 73–96 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: CHD Clear all
Completed Phase 3 Interventional Results available

Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)

NCT00065806
View directory record Official record
Conditions
Lupus Erythematosus, Systemic
Interventions
Atorvastatin, Placebo atorvastatin
Drug
Lead sponsor
Laura Schanberg
Other
Eligibility
10 Years to 21 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Oct 30, 2026, 6:55 AM EDT
Withdrawn No phase listed Observational

Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making

NCT02158754
View directory record Official record
Conditions
Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases, CAD, CVD, Coronary Heart Disease, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
9
States / cities
Rutherford, New Jersey • Wake Forest, North Carolina • Youngstown, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

New Heart Imaging Techniques to Evaluate Possible Heart Disease

NCT01399385
View directory record Official record
Conditions
Healthy, Obesity, Diabetes, Healthy Volunteers, Atherosclerosis
Interventions
MR Imaging Techniques - 1, MR Imaging Techniques - 2, MR Imaging Techniques - 3, MR Imaging Techniques - 4
Device
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 100 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Phase 2 Interventional Results available

Vet-Harts Pilot Intervention for Veterans With Coronary Heart Disease

NCT01566214
View directory record Official record
Conditions
Heart Disease
Interventions
Motivational Interview
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 30, 2026, 6:55 AM EDT
Completed No phase listed Observational

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)

NCT01117506
View directory record Official record
Conditions
Coronary Artery Disease, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, Angina Pectoris, CAD, CVD, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
35 Years to 90 Years
Enrollment
581 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
7
States / cities
Long Beach, California • Roseville, California • Boulder, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Phase 3 Interventional Results available

Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD)

NCT03852719
View directory record Official record
Conditions
Chronic Hepatitis Delta
Interventions
Bulevirtide
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting Not applicable Interventional

Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

NCT07582861
View directory record Official record
Conditions
Congenital Heart Disease (CHD)
Interventions
HeartGPS
Other
Lead sponsor
Carelon Research
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
17
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Completed No phase listed Observational

Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern

NCT01251302
View directory record Official record
Conditions
Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, CAD, CVD, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years to 99 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 30, 2026, 6:55 AM EDT
Completed No phase listed Observational

Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis

NCT02352675
View directory record Official record
Conditions
Congenital Heart Disease, Fibrinolysis, Rotational Thromboelastometry
Interventions
Intraoperative Blood Sample
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Months to 12 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart to Health: A Combined Lifestyle and Medication Intervention to Reduce Cardiovascular Disease (CVD) Risk

NCT01245686
View directory record Official record
Conditions
Cardiovascular Disease, Coronary Heart Disease
Interventions
Lifestyle and medication intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 79 Years
Enrollment
489 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
5
States / cities
Durham, North Carolina • Eden, North Carolina • Kannapolis, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2013 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting No phase listed Observational

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

NCT06932081
View directory record Official record
Conditions
Adult Congenital Heart Disease, Congenital Heart Disease, Systemic Right Ventricle, Transposition of the Great Arteries, Congenitally Corrected Transposition of the Great Arteries, Fontan, Single Ventricle, Tetralogy of Fallot (TOF)
Interventions
SGLT2 inhibitors
Drug
Lead sponsor
Leiden University Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting No phase listed Observational

Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment

NCT05213598
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2051
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Not applicable Interventional

Intestinal Function in Neonates With Complex Congenital Heart Disease

NCT01475357
View directory record Official record
Conditions
Congenital Heart Defects, Growth Failure
Interventions
Arm 1: NPO by mouth pre-operative, Arm 2: Fresh Breast Milk pre-operative
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
37 Weeks to 40 Weeks
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Oct 30, 2026, 6:55 AM EDT
Completed No phase listed Observational

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree

NCT00500617
View directory record Official record
Conditions
Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, CAD, CVD, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years to 99 Years
Enrollment
4,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
10
States / cities
Anchorage, Alaska • Beverly Hills, California • La Jolla, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting Not applicable Interventional

A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

NCT07525843
View directory record Official record
Conditions
Patient-Reported Outcome Measures (PROMs), Pragmatic Trial, Adolescent Congenital Heart Disease, Resiliency-building Intervention, Resilience, Psychological, Telemedicine-Based Education
Interventions
Telemedicine-based resiliency-building intervention
Behavioral
Lead sponsor
Carelon Research
Other
Eligibility
12 Years to 17 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
14
States / cities
Stanford, California • Aurora, Colorado • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting Not applicable Interventional

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

NCT06175104
View directory record Official record
Conditions
Heart Defects, Congenital, Anxiety in Pregnancy, Depression, Postpartum, Trauma, Psychological, Neurodevelopmental Disorders
Interventions
HeartGPS
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 30, 2026, 6:55 AM EDT
Active, not recruiting Not applicable Interventional Results available

Xeltis Bioabsorbable Pulmonary Valved Conduit Pivotal Study

NCT03022708
View directory record Official record
Conditions
Heart Defect, Congenital
Interventions
Xeltis Bioabsorbable Pulmonary Valved Conduit
Device
Lead sponsor
Xeltis
Industry
Eligibility
2 Years to 21 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
7
States / cities
Los Angeles, California • Aurora, Colorado • Hollywood, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD

NCT05186415
View directory record Official record
Conditions
Tetralogy of Fallot, Pulmonary Insufficiency
Interventions
Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
11 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 30, 2026, 6:55 AM EDT
Terminated No phase listed Observational

Infection in DiGeorge Following CHD Surgery

NCT00278005
View directory record Official record
Conditions
DiGeorge Syndrome, Congenital Heart Defects
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 15 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 30, 2026, 6:55 AM EDT
Terminated No phase listed Observational

Percutaneous Interventions in Adults With CHD

NCT00266916
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 23, 2007 · Synced Oct 30, 2026, 6:55 AM EDT
Terminated No phase listed Observational

Using Tissue Doppler/Synchronization to Determine Heart Function in Children With Congenital Heart Disease

NCT00208676
View directory record Official record
Conditions
Congenital Heart Defects
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
Up to 21 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 30, 2026, 6:55 AM EDT
Terminated No phase listed Observational

Critical Congenital Heart Defect (CHD) Outcomes in Children

NCT00208689
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
1 Day to 21 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Oct 30, 2026, 6:55 AM EDT
Completed Phase 3 Interventional Results available

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

NCT01000727
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Darapladib 160 mg, Placebo, Standard Therapy
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
13,026 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
290
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 252 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Oct 30, 2026, 6:55 AM EDT
Recruiting Not applicable Interventional

HFNC vs NIPPV Following Extubation

NCT05869825
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation
Procedure
Lead sponsor
Emory University
Other
Eligibility
Up to 1 Year
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 30, 2026, 6:55 AM EDT