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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CM/abstinence+CBT Clear all
Not yet recruiting Not applicable Interventional

Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

NCT07714200
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion, Varenicline, Mobile Contingency Management, Clinic-Based Smoking Cessation Counseling
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 4 Interventional Results available

CPT-SMART for Treatment of PTSD and Cigarette Smoking

NCT03978442
View directory record Official record
Conditions
Smoking, Stress Disorders, Post-Traumatic
Interventions
Smoking Cessation Cognitive Behavioral Therapy (CBT), Bupropion, Cognitive Processing Therapy, Smoking Abstinence Reinforcement Therapy, Yoked Contingency Management
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 2 Interventional

Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management

NCT00350649
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Standard CBT, CBT+CM/adherence, CM/abstinence, CM/abstinence+CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 26, 2011 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Results available

Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence

NCT00713583
View directory record Official record
Conditions
Cocaine Dependence
Interventions
levodopa, Placebo, Cognitive Behavioral Therapy, Contingency Management
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 22, 2018 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Smoking Cessation Intervention for Smokers With Depression Receiving Outpatient Psychiatric Treatment

NCT02742610
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mindfulness with Contingency Management, Active Control
Behavioral
Lead sponsor
Fordham University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 4 Interventional Results available

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

NCT02995915
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment, Mobile Contingency Management, Mobile Monitoring
Other · Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 10, 2026, 3:34 AM EDT
Active, not recruiting Phase 3 Interventional

Treating Polysubstance Use Using a Novel Digital Technology

NCT05766631
View directory record Official record
Conditions
Opioid Use, Opioid Use Disorder, Cocaine Use, Cocaine Use Disorder
Interventions
DynamiCare Health, Methadone Treatment-As-Usual
Behavioral · Drug
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Results available

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

NCT02896712
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Acceptance and Commitment Therapy (ACT), Drug Counseling (DC), Contingency Management (CM), Placebo, Modafinil
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 10, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Virtual Incentive Treatment for Alcohol

NCT06265506
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions
Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Medications for Stopping Cocaine Dependence and Preventing Relapse

NCT00218023
View directory record Official record
Conditions
Cocaine Abuse, Cocaine-Related Disorders
Interventions
Modafinil, Levodopa/Carbidopa, Naltrexone HCl, Placebo, Motivational Interviewing (MI), Contingency management (CM), Cognitive-Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 55 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 10, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Smoking Cessation CM for Veterans With or at Risk for Cancer

NCT06432985
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorder
Interventions
Focus Group, Contingency Management, Behavioral Counseling (Cognitive Behavioral Therapy, CBT), TUD Treatment as Usual (TAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 1 Interventional

Cognitive-Behavioral Treatment of Gambling

NCT00118391
View directory record Official record
Conditions
Gambling, Mental Health
Interventions
Cognitive behavior therapy, Contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Not applicable Interventional

OUD Smartphone Services

NCT06134882
View directory record Official record
Conditions
Opioid-Related Disorders, Drug Abuse
Interventions
Contingency management, Cognitive-Behavior Therapy Modules, Peer Contingency Management (CM) Guide, Drug testing, Wellness modules, Peer technical support
Behavioral
Lead sponsor
Western Michigan University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder

NCT03987581
View directory record Official record
Conditions
Alcohol Drinking, Veterans
Interventions
Cognitive Behavioral Therapy (CBT), Mobile Contingency Management (mCM), Long-term incentive
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pharmacotherapy & CM for Opioid and Cocaine Dependence

NCT00838981
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Modafinil, Sugar Pill, Contingency Management, Methadone, cognitive behavioral treatment, Voucher Control
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Family and Adolescent Motivational Incentives for Leveraging Youth

NCT01736995
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Functional Family Therapy, Motivational Enhancement Tx/Cognitive Behavioral Tx, Contingency Management
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 10, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment for Adolescent Marijuana Abuse

NCT00580671
View directory record Official record
Conditions
Marijuana Abuse
Interventions
MET/CBT, CM, BPT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Sep 10, 2026, 3:34 AM EDT