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ClinicalTrials.gov public records Last synced Oct 10, 2026, 7:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 76 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: CO2 Laser Treatment Clear all
Not yet recruiting Not applicable Interventional

Intraoperative CO₂ (Carbon Dioxide)

NCT07592468
View directory record Official record
Conditions
Wound Edges
Interventions
CO2 Fractionated Laser, Non CO2 Laser Treatment
Device · Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

NCT01529983
View directory record Official record
Conditions
Wrinkles
Interventions
Laser treatment, High-intensity focused ultrasound
Procedure · Device
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 10, 2026, 7:23 PM EDT
Terminated Not applicable Interventional Results available

Study of Mitomycin-C Application in Laryngotracheal Stenosis

NCT01523275
View directory record Official record
Conditions
Laryngeal Stenosis, Subglottic Stenosis, Tracheal Stenosis
Interventions
Mitomycin -C, Saline application
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 10, 2026, 7:23 PM EDT
Withdrawn Not applicable Interventional

A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women

NCT04253067
View directory record Official record
Conditions
Stress Urinary Incontinence, Urinary Incontinence
Interventions
Active fCO2 laser treatment, Sham fCO2 laser treatment
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 75 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia

NCT02875561
View directory record Official record
Conditions
Vulvar Intraepithelial Neoplasia (VIN)
Interventions
Sonopet Ultrasonic Aspirator, CO2 Laser Ablation
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Aurora, Colorado • Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 10, 2026, 7:23 PM EDT
Active, not recruiting Not applicable Interventional

Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

NCT04996173
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Spray cryotherapy, Ballon Dilation, Radial Incision
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Jackson, Mississippi • Nashville, Tennessee • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)

NCT00992277
View directory record Official record
Conditions
Aesthetic Dermatology
Interventions
Ablation and skin resurfacing
Procedure
Lead sponsor
Syneron Medical
Industry
Eligibility
20 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
3
States / cities
San Diego, California • Tustin, California • Saint Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 10, 2026, 7:23 PM EDT
Withdrawn Phase 2 Interventional

Laser Assisted Delivery of Minoxidil in Androgenetic Alopecia

NCT03852992
View directory record Official record
Conditions
Male Pattern Hair Loss, Androgenetic Alopecia, Male Pattern Baldness
Interventions
Post-Laser Minoxidil 2%, At-Home Minoxidil 5%, Laser, Post-laser 5mg minoxidil, Post-laser 10mg minoxidil, Post-laser 20mg minoxidil
Drug · Device
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 10, 2026, 7:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy

NCT04737616
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
CO2 laser, OCT
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Oct 10, 2026, 7:23 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue

NCT01026662
View directory record Official record
Conditions
Abdominoplasty
Interventions
Ablation and skin resurfacing, eMatrixCO2
Procedure · Device
Lead sponsor
Syneron Medical
Industry
Eligibility
20 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Open-Label, Single-Center, Non-Comparative Study to Assess the Use of Pixel CO2 Laser System (FemiLift) in the Treatment of Vulvovaginal Atrophy (VVA) in Postmenopausal Female Subjects

NCT02747641
View directory record Official record
Conditions
Atrophy, Vaginal Atrophy, Genital Diseases, Female
Interventions
Pixel CO2 Laser System
Procedure
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 70 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

The CO2RE® System for Vulvar Lichen Sclerosus

NCT04148651
View directory record Official record
Conditions
Vulvar Lichen Sclerosus
Interventions
The CO2RE® System
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Jacksonville, Florida • Cincinnati, Ohio • South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Hyaluronidase Via LADD Scleroderma-induced Microstomia

NCT05995626
View directory record Official record
Conditions
Microstomia, Scleroderma
Interventions
Hyaluronidase, CO2 laser
Drug · Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 10, 2026, 7:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy

NCT03271944
View directory record Official record
Conditions
Vulvovaginal Atrophy
Interventions
CO2 Laser Treatment
Device
Lead sponsor
SHERRY Thomas
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Agoura Hills, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2018 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post Excision/Mohs Scar Laser Resurfacing

NCT02130297
View directory record Official record
Conditions
Skin Cancer
Interventions
Laser Treatment
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional

CO2 Laser Phototherapy for Management of Mature Burn Scars

NCT03197649
View directory record Official record
Conditions
Burn Scar
Interventions
Laser phototherapy treatment
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
3 Years to 21 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional

Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

NCT03307044
View directory record Official record
Conditions
Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia, Vaginal Dryness
Interventions
Laser Therapy, Questionnaire Administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids

NCT02996097
View directory record Official record
Conditions
Keloid
Interventions
The Lutronic electronic carbon dioxide (eCO2) Plus laser system, Intralesional Triamcinolone Acetonide
Device · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 10, 2026, 7:23 PM EDT
Recruiting Phase 3 Interventional

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

NCT05379153
View directory record Official record
Conditions
Vaginal Atrophy, Breast Carcinoma
Interventions
Laser Therapy, Sham Intervention, Questionnaire Administration, Quality of Life Assessment
Device · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
22 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation

NCT00792688
View directory record Official record
Conditions
Wounds
Interventions
GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%), GLYC-101 Placebo
Drug
Lead sponsor
TR Therapeutics
Industry
Eligibility
25 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Laser Resurfacing Versus Dermabrasion for Scar Revision

NCT01176448
View directory record Official record
Conditions
Cicatrix, Dermabrasion, Coagulation, Laser
Interventions
Fractionated laser, Dermabrasion
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women

NCT05336825
View directory record Official record
Conditions
Vulvodynia
Interventions
CO2 laser, Lidocaine patch 5%
Device · Drug
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Denville, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection

NCT04301934
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Mona Lisa Touch, Conjugated estrogen, Estradiol
Device · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Oct 10, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation

NCT06366503
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer, Sunscreen, Basic Ointment
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 10, 2026, 7:23 PM EDT