Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 4, 2026, 8:56 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: CO2 fractional laser Clear all

Conditions: Male Pattern Hair Loss, Androgenetic Alopecia, Male Pattern Baldness
Interventions: Post-Laser Minoxidil 2%, At-Home Minoxidil 5%, Laser, Post-laser 5mg minoxidil, Post-laser 10mg minoxidil, Post-laser 20mg minoxidil; Drug · Device
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 65 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Wounds and Injury
Interventions: NanoDOX® Hydrogel, CO2 Ablative Fractional Laser; Drug · Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions: CO2 Laser, Ultrasound, Skin Biopsy; Device · Radiation · Diagnostic Test
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Genitourinary Syndrome of Menopause
Interventions: CO2 laser, OCT; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Irvine, California

Conditions: Lichen Sclerosus
Interventions: FxCO2 Laser, Sham Laser; Device
Lead sponsor: Center for Vulvovaginal Disorders; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Poikiloderma of Civatte
Interventions: DEKA SmartXide C02 laser; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Burn Scar, Skin Graft Scar
Interventions: Lidocaine Cream, Triamcinolone Acetonide Cream, Fractional Ablative Laser; Drug · Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Genitourinary System; Disorder, Female, Burning Vagina, Dyspareunia, Irritation; Vagina, Menopause Related Conditions, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Tract Infections, Stress Urinary Incontinence
Interventions: fCO2 Laser Therapy Group; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 90 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Atrophic Vaginitis, Menopause
Interventions: CO2 fractionated vaginal laser, Estrogens, Conjugated (USP); Device · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: Female only
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 6
States / cities: Stanford, California • Washington D.C., District of Columbia • Winston-Salem, North Carolina + 3 more

Conditions: Vaginal Atrophy
Interventions: CO2RE; Device
Lead sponsor: Syneron Medical; Industry
Eligibility: 35 Years and older · Female only
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 4
States / cities: Jacksonville, Florida • Louisville, Kentucky • Wayland, Massachusetts + 1 more

Conditions: Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia, Vaginal Dryness
Interventions: Laser Therapy, Questionnaire Administration; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Female only
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Vulvodynia
Interventions: CO2 laser, Lidocaine patch 5%; Device · Drug
Lead sponsor: Atlantic Health System; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Denville, New Jersey

Conditions: Vestibulodynia
Interventions: Fractional CO2 Laser Treatment, Sham Laser Treatment; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Cicatrix, Carbon Dioxide Laser
Interventions: Syneron-Candela CO2RE Laser; Device
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hair Reduction, Tattoo Removal, Wrinkle, Acne, Scars, Benign Cutaneous Vascular Lesions, Skin Conditions
Interventions: Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE; Device
Lead sponsor: Candela Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2029
U.S. locations: 2
States / cities: Jacksonville, Florida • Marlborough, Massachusetts

Conditions: Dyspareunia
Interventions: 4% Topical Lidocaine Gel, CO2RE fractional laser therapy; Drug · Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cicatrix, Dermabrasion, Coagulation, Laser
Interventions: Fractionated laser, Dermabrasion; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Edina, Minnesota

Conditions: Burn Scar, Scar, Skin Graft Scar
Interventions: Fractional CO2 Laser; Procedure
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Genitourinary Syndrome of Menopause
Interventions: MonaLisa Touch; Device
Lead sponsor: Michigan Institution of Women's Health PC; Other
Eligibility: Female only
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Dearborn, Michigan

Conditions: Genitourinary Syndrome of Menopause
Interventions: Optical coherence tomography (OCT); Diagnostic Test
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Healthy
Interventions: DFG Laser, CO2 Laser, Optical coherence tomography (OCT); Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Wound Healing
Interventions: Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser; Other · Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Scar
Interventions: Fraxel Laser, CO2 Laser; Device
Lead sponsor: Marta Hemmingson-Van Beek; Other
Eligibility: 18 Years to 120 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Wrinkle
Interventions: Fraxel Laser Treatment; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Dallas, Texas

Search by objective public record fields.

Laser Assisted Delivery of Minoxidil in Androgenetic Alopecia

Investigation of Laser Assisted Drug Delivery of NanoDOX®

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy

MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus

The Effects of Fractional CO2 Laser on Poikiloderma of Civatte

Fractional Ablative Laser Treatment for Skin Grafts

Laser Therapy for Treatment of Urogenital Symptoms in Women

Comparison of Vaginal Laser Therapy to Vaginal Estrogen Therapy

Clinical Study of the CO2RE Laser Device Performance for Vaginal Atrophy Treatments

Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women

Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy

Clinical Study to Evaluate the Safety and Efficacy of Candela Technology

Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors

Laser Resurfacing Versus Dermabrasion for Scar Revision

CO2 Laser Revision for Burn Related Donor Site Scars

MonaLisa Touch Randomized Double-Blind Placebo Controlled Study

Vaginal Changes After CO2 Laser

A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser

Compression and CO2 Laser for Leg Wounds

Comparison of Lasers in the Treatment of Scars

Fractional CO2 Laser System (Fraxel Repair Laser) Intended for Treatment of Perioral Rhytides/Wrinkles