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Showing 1–24 of 171 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CONTROL Contact Lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Orthokeratology in Myopia Control

NCT03465748
View directory record Official record
Conditions
Myopia
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
6 Years to 13 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 4, 2026, 4:40 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process

NCT03605303
View directory record Official record
Conditions
Refractive Error Correction
Interventions
Test/Control, Control/Test
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers

NCT04668989
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Athens, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types

NCT06232590
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a Daily Disposable Contact Lens

NCT01192126
View directory record Official record
Conditions
Myopia, Contact Lenses
Interventions
Bausch & Lomb new daily disposable, Johnson & Johnson Acuvue Moist
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2014 · Synced Sep 4, 2026, 4:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control

NCT04080128
View directory record Official record
Conditions
Myopia
Interventions
Contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 4, 2026, 4:40 AM EDT
Recruiting Not applicable Interventional

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

NCT07408154
View directory record Official record
Conditions
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Interventions
Direct Selective laser Trabeculoplasty
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Phase 2 Interventional

Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel

NCT03994406
View directory record Official record
Conditions
Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining
Interventions
CLM2 topical gel, Placebo topical gel
Drug
Lead sponsor
Glia, LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Sep 4, 2026, 4:40 AM EDT
Recruiting Phase 1Phase 2 Interventional

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

NCT04225611
View directory record Official record
Conditions
Cystoid Macular Edema
Interventions
Dexamethasone
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT02719366
View directory record Official record
Conditions
Presbyopia
Interventions
comfilcon A Extended Range test lens, comfilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Bifocal Lenses In Nearsighted Kids

NCT02255474
View directory record Official record
Conditions
Refractive Errors
Interventions
Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
Device
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 11 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses

NCT02423109
View directory record Official record
Conditions
Myopia, Hyperopia, Astigmatism
Interventions
fanfilcon A, enfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
17 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study

NCT05582304
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line

NCT04794270
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
5
States / cities
Longwood, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression

NCT01423773
View directory record Official record
Conditions
Ocular Comfort
Interventions
Lotrafilcon A test contact lens, Lotrafilcon A control contact lens, Ultra-High Resolution Optical Coherence Tomographer (OCT)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 4, 2026, 4:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial

NCT05159765
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lenses, Multifocal contact lenses
Device
Lead sponsor
Visioneering Technologies, Inc
Industry
Eligibility
7 Years to 13 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
4
States / cities
Fresno, California • Deerfield, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Results available

Dispensing Study for a New Study Lens

NCT02642991
View directory record Official record
Conditions
Myopia
Interventions
Phenacite, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05502289
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 4, 2026, 4:40 AM EDT
Active, not recruiting Phase 2 Interventional

Myopia Control: a Comparison Study Between Atropine and MiSight

NCT05815784
View directory record Official record
Conditions
Myopia
Interventions
Atropine, MiSight contact lenses
Drug · Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 4, 2026, 4:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
View directory record Official record
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Sep 4, 2026, 4:40 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Visual Performance of Soft Contact Lenses With Myopia Control Optics

NCT05141448
View directory record Official record
Conditions
Visual Acuity
Interventions
1-Day Acuvue Moist, EMO-118, EMO-114, MiSight® 1 day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 4, 2026, 4:40 AM EDT