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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CONTROL Contact Lens Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05502289
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Manufacturing Technology

NCT03962790
View directory record Official record
Conditions
Visual Acuity
Interventions
1-DAY ACUVUE® MOIST
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Maitland, Florida • Bloomington, Illinois • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.

NCT05361304
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A contact lenses made with a novel manufacturing technology, senofilcon A contact lenses made with the current manufacturing technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Performance of Senofilcon A Investigational Lens

NCT05300763
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A prototype, Dailies Total 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
19
States / cities
San Francisco, California • Jacksonville, Florida • Longwood, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 9, 2026, 12:03 PM EDT
Active, not recruiting Phase 2 Interventional

Myopia Control: a Comparison Study Between Atropine and MiSight

NCT05815784
View directory record Official record
Conditions
Myopia
Interventions
Atropine, MiSight contact lenses
Drug · Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

1 Week Crossover Study Between Two Soft Contact Lenses

NCT06611410
View directory record Official record
Conditions
Myopia
Interventions
Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Dispensing Evaluation of Subjective Comfort, Vision, and Handling of a New Lens Compared to a Marketed Lens

NCT01484054
View directory record Official record
Conditions
Refractive Ametropia
Interventions
etafilcon A with print and PVP for dark eyes (EAPVPDE), etafilcon A control lens (EADE)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 34 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
6
States / cities
Bloomfield, Connecticut • Tallahassee, Florida • Overland Park, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Silicone Hydrogel Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05258149
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lenses, Dailies Total 1® Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear

NCT04050618
View directory record Official record
Conditions
Myopia
Interventions
fanfilcon A test lens, ocufilcon D control lens, etafilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
6
States / cities
Whittier, California • Longwood, Florida • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)

NCT01829191
View directory record Official record
Conditions
Myopia
Interventions
Soft Contact Test Lens A, Soft Contact Test Lens C
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Hyperopic Population

NCT04567186
View directory record Official record
Conditions
Visual Acuity
Interventions
Investigational senofilcon A C3 Multifocal Lens, delefilcon A Multifocal Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Bakersfield, California • Mission Viejo, California • Jacksonville, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daily Disposable Dispensing Clinical Trial of Test Lens Against Stenfilcon A Lens

NCT03024970
View directory record Official record
Conditions
Myopia
Interventions
stenfilcon A lens with solution additive (test), stenfilcon A lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Bloomington, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients

NCT05661851
View directory record Official record
Conditions
Dry Eye
Interventions
Investigational Lubricating Eye Drop in a Novelia® bottle, Blink® Tears eye Drops
Drug
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
8
States / cities
Jacksonville, Florida • Pittsburg, Kansas • Medina, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Tangible Boost Replenishing System

NCT03073148
View directory record Official record
Conditions
Contact Lens Solution
Interventions
Tangible Boost, Placebo saline
Device · Other
Lead sponsor
Tangible Science
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Clinical Evaluation of an Investigational Lipid Drop in Non-contact Lens Wearing Patients

NCT03995355
View directory record Official record
Conditions
Visual Acuity
Interventions
9618X investigational lipid eye drops, Blink® Tears
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses

NCT02537522
View directory record Official record
Conditions
Contact Lens Base Curve (BC) Fit and Comfort
Interventions
Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 9, 2026, 12:03 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Studying the Relationship Between Contact Lens Packaging Solutions and Bacterial Binding to Surface Eye Cells

NCT01104961
View directory record Official record
Conditions
Corneal Ulcer
Interventions
Contact lens packaging solution, Balanced salt solution (BSS)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 38 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 9, 2026, 12:03 PM EDT
Completed No phase listed Interventional Results available

A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens

NCT03499067
View directory record Official record
Conditions
Myopia
Interventions
Test lens, Control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Berkeley, California • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved and Investigational Contact Lenses

NCT02669095
View directory record Official record
Conditions
Visual Disorder
Interventions
Investigational Contact Lenses (Test), Marketed Contact Lenses (Control)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Sarasota, Florida • Winter Park, Florida • Pickens, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock

NCT05713552
View directory record Official record
Conditions
Ocular Physiology
Interventions
Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock, Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions

NCT01791517
View directory record Official record
Conditions
Contact Lens Solutions
Interventions
Solution 1 (Test), Solution 2 (Test), Solution 3 (Test), Solution 4 (Control)
Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens

NCT04189224
View directory record Official record
Conditions
Presbyopia
Interventions
JJV Investigational Multifocal Contact Lens, 1-Day Acuvue® Moist Brand Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Maitland, Florida • Raytown, Missouri • Granville, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.

NCT02759471
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A sphere lens (control), comfilcon A asphere lens (test)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Whittier, California • Medina, Minnesota • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 9, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Objective Vision Evaluation of Two Cosmetic Contact Lenses

NCT04287036
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Contact Lens, 1-DAY ACUVUE® DEFINE® Radiant Sweet™
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 9, 2026, 12:03 PM EDT