Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 2:44 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: CPAP/BiPAP Clear all

Conditions: Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure, Neuromuscular Disease Patients, Neuromuscular Disease, Respiratory Insufficiency, Respiratory Insufficiency Requiring Mechanical Ventilation, Positive Pressure Ventilation, Non-invasive Ventilation, Non-invasive Ventilation Support, Non-invasive Ventilatory Support
Interventions: Non-invasive ventilation; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Hershey, Pennsylvania • Philadelphia, Pennsylvania • Philadelphi, Pennsylvania

Conditions: Chronic Respiratory Failure
Interventions: Nasal non-invasive ventilation with RAM cannula; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 1 Day to 21 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Multiple Sclerosis
Interventions: PAP therapy; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 70 Years
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pediatric Asthma, Acute Asthma, BiPAP, Non-invasive Positive Pressure Ventilation
Interventions: Bilevel positive airway pressure ventilation; Device
Lead sponsor: Columbia University; Other
Eligibility: 5 Years to 17 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: New York, New York • Columbus, Ohio • Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea of Adult
Interventions: structured adherence management program, Standard of care; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 85 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Interventions: noninvasive positive pressure ventilation; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: COVID-19
Interventions: Respiratory supports; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 2,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Sickle Cell Anemia, Acute Chest Syndrome
Interventions: Bi-level positive airway pressure device, Sham CPAP; Device
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 4 Years to 21 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Parainfluenza
Interventions: DAS181-F02 Dry Powder in Bulk, DAS181-F02 Nebulized Formulation Inhaled Dose; Drug
Lead sponsor: Ansun Biopharma, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 23
States / cities: Duarte, California • Orange, California • Palo Alto, California + 18 more

Conditions: Sleep Disordered Breathing
Interventions: CPAP/BiPAP; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 8 Years to 18 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Hypoxic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
Interventions: Non-Invasive Positive Pressure Ventilation, High Flow Nasal Oxygen; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 6
States / cities: Tucson, Arizona • Ann Arbor, Michigan • Columbus, Ohio + 2 more

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Early NIPPV, Standard NIPPV; Device
Lead sponsor: Edward Kasaraskis; Other
Eligibility: 18 Years to 80 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2012
U.S. locations: 12
States / cities: Denver, Colorado • Miami, Florida • Lexington, Kentucky + 8 more

Conditions: COVID -19, Respiratory Failure, Hypoxia
Interventions: Oxygen Hood; Device
Lead sponsor: Northwell Health; Other
Eligibility: Not listed
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Sleepy Hollow, New York

Conditions: Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
Interventions: Bipap procedure; Procedure
Lead sponsor: United States Air Force; Federal
Eligibility: 35 Years to 80 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Wpafb, Ohio

Conditions: Asthma, Sleep Apnea
Interventions: Bilevel PAP (4 weeks), Usual Care (4 weeks), Washout Period (4 weeks); Device · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Apnea Syndromes
Interventions: servo ventilation auto, Continuous positive airway pressure, servo ventilation manual; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 4
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Atlanta, Georgia + 1 more

Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Bilevel positive airway pressure (BiPAP); Device
Lead sponsor: Philips Respironics; Industry
Eligibility: Up to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Lung Carcinoma, Malignant Respiratory Tract Neoplasm, Metastatic Malignant Neoplasm in the Lung
Interventions: Biphasic Positive Airway Pressure, Computed Tomography, Continuous Positive Airway Pressure, Deep Inspiration Breath Hold, Radiation Therapy Treatment Planning and Simulation, Stereotactic Body Radiation Therapy; Device · Procedure · Radiation
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Obstructive Sleep Apnea
Interventions: CPAP or BiPAP machines; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pneumonia, Ventilator-Associated, Pneumonia, Bacterial, Pneumonia, Hospital-Acquired
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 7,530 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 15
States / cities: Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 12 more

Conditions: Obesity Hypoventilation Syndrome
Interventions: AVAPS-AE Mode of Therapy, Respironics OnmiLab BiPAP S mode, Respironics OmniLab Advanced CPAP mode; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Tucson, Arizona • Chicago, Illinois

Conditions: COPD
Interventions: Bipap (Respironics, Inc); Device
Lead sponsor: University of Iowa; Other
Eligibility: 35 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Obstructive Sleep Apnea
Interventions: Bi-Flex, CPAP; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 2 Years to 16 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BiPAP Synchrony ventilator; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting

CPAP to Treat Cognitive Dysfunction in MS

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

ThErapy Adherence Management in Veterans

Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis

Respiratory Supports and COVID-19 Mortality

Bi-Level Positive Airway Ventilation for Acute Chest Syndrome

An Open Label Study to Examine the Effects of DAS181 Administered by Dry Powder Inhaler (DPI) or Nebulized Formulation in Immunocompromised Subjects With Parainfluenza (PIV) Infection

Continuous Positive Airway Pressure and Cardiometabolic Risk

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

Use of Oxygen Hoods in Patients Failing on Conventional High-flow Oxygen Delivery Systems, Effects on Oxygenation in Hypoxic COVID-19 Patients. Prospective Cohort Study.

Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome

Positive Airway Pressure for the Treatment of Asthma

Sleep Disordered Breathing and Chronic Pain

High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Face of Sleepiness

CTTI Risk Factors for HABP/VABP Study

AVAPS-AE Efficacy Study

Trial of Non-invasive Ventilation for Stable COPD

Evaluation of Adherence and Therapeutic Effectiveness of Bi-Flex Versus CPAP in Children With OSA

The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants