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ClinicalTrials.gov public records Last synced Oct 29, 2026, 2:50 AM EDT

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Showing 1–24 of 285 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: CPAP Therapy Clear all
Completed Not applicable Interventional Results available

Sleep Disordered Breathing and Chronic Pain

NCT01457014
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
servo ventilation auto, Continuous positive airway pressure, servo ventilation manual
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 70 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 29, 2026, 2:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Aspirin Resistance in OSA Patients

NCT03930875
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Aspirin Resistance testing
Other
Lead sponsor
Danbury Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danbury, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Treating Obese and Lean Patients With Sleep Apnea

NCT01578031
View directory record Official record
Conditions
Sleep Apnea, Obesity
Interventions
Positive Airway Pressure During Sleep (ResMed S9 Elite), Usual Care
Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 65 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Terminated Not applicable Interventional Results available

High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation

NCT01270581
View directory record Official record
Conditions
Transient Tachypnea of the Newborn
Interventions
High Flow Nasal Cannula, Bubble Nasal CPAP
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Oct 29, 2026, 2:50 AM EDT
Active, not recruiting No phase listed Observational

Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype

NCT05742360
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP therapy
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Columbus, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional

ThErapy Adherence Management in Veterans

NCT03243487
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
structured adherence management program, Standard of care
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional

The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia

NCT01622647
View directory record Official record
Conditions
Knee Replacement Surgery
Interventions
Nasal Continuous Positive Airway Pressure (NCPAP)
Other
Lead sponsor
Pediatrix
Other
Eligibility
21 Years to 69 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2013 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Phase 2 Interventional Results available

Effects of Treating Obstructive Sleep Apnea in Epilepsy

NCT00047463
View directory record Official record
Conditions
Epilepsy, Sleep Apnea, Obstructive Sleep Apnea
Interventions
continuous positive airway pressure (CPAP), Placebo-CPAP
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
4
States / cities
Ann Arbor, Michigan • Chapel Hill, North Carolina • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2016 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

NCT02514798
View directory record Official record
Conditions
COPD
Interventions
Esophageal and gastric balloons, Respiratory Inductance Plethysmography (RIP) system, Sentec transcutaneous monitoring system, High-flow humidified nasal oxygen delivery system, CPAP (Positive Control)
Other · Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 29, 2026, 2:50 AM EDT
Active, not recruiting Not applicable Interventional

Mechanisms of Prediabetic States in Sleep Apnea

NCT04234217
View directory record Official record
Conditions
Sleep Apnea, Pre-diabetes
Interventions
Continuous positive airway pressure, Niacin
Device · Other
Lead sponsor
University of Chicago
Other
Eligibility
20 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 29, 2026, 2:50 AM EDT
Withdrawn Not applicable Interventional

Effects of PAP Treatment of OSA in Patients With Heart Failure

NCT01136122
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP Treatment
Device
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea

NCT00859950
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypoxemia
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Enrolling by invitation Not applicable Interventional

Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

NCT07176117
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Surfactant
Interventions
Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA), Continuous Positive Airway Pressure (CPAP)
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
33 Weeks to 38 Weeks
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
3
States / cities
Chula Vista, California • La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 29, 2026, 2:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Continuous Positive Airway Pressure on Peripheral Oxygen Saturation, Work of Breathing, and Exercise Tolerance at Altitude

NCT05971290
View directory record Official record
Conditions
Hypoxemia, Altitude Hypoxia
Interventions
Continuous positive airway pressure, Ambient air
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Results available

CPAP vs ASV for Insomnia

NCT02365064
View directory record Official record
Conditions
Insomnia, Sleep-Disordered Breathing
Interventions
AirCurve 10 ASV
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 9, 2021 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Sleep Apnea on Risk of Atrial Fibrillation

NCT02576587
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Continuous Positive Airway Pressure
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional

Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery

NCT01697878
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 29, 2026, 2:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents

NCT01840618
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
Interventions
Nasal Continuous positive airway pressure (CPAP)
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Results available

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351
View directory record Official record
Conditions
Obstructive Sleep Apnea, Mild Cognitive Impairment
Interventions
CPAP adherence intervention, Attention control intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
55 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Continuous Airway Pressure on the Ability to Heat and Humidify Air

NCT00338403
View directory record Official record
Conditions
Healthy
Interventions
Continuous positive airway pressure (CPAP) at -5, 0, 5 and 10 cm of water
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Results available

Race And CPAP Effectiveness

NCT01960465
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 70 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 29, 2026, 2:50 AM EDT
Recruiting Phase 3 Interventional

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

NCT05960929
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
Interventions
Infasurf Aero™
Combination Product
Lead sponsor
ONY
Industry
Eligibility
29 Weeks to 36 Weeks
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
10
States / cities
Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 29, 2026, 2:50 AM EDT
Recruiting Not applicable Interventional

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

NCT03422302
View directory record Official record
Conditions
Lung Carcinoma, Malignant Respiratory Tract Neoplasm, Metastatic Malignant Neoplasm in the Lung
Interventions
Biphasic Positive Airway Pressure, Computed Tomography, Continuous Positive Airway Pressure, Deep Inspiration Breath Hold, Radiation Therapy Treatment Planning and Simulation, Stereotactic Body Radiation Therapy
Device · Procedure · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 29, 2026, 2:50 AM EDT
Completed Not applicable Interventional Results available

Metabolic Impact of Intermittent CPAP

NCT02824263
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP withdrawal
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 75 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 29, 2026, 2:50 AM EDT