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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: CPAP therapy Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Sleep Apnea on Risk of Atrial Fibrillation

NCT02576587
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Continuous Positive Airway Pressure
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Phase 3 Interventional Results available

Apnea Positive Pressure Long-Term Efficacy Study

NCT00051363
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Sleep
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
5
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Modulation Of Airway Reactivity With Chronic Mechanical Strain

NCT02396849
View directory record Official record
Conditions
Asthma
Interventions
Continuous Positive Airway Pressure (CPAP), Continuous Positive Airway Pressure (CPAP) Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 15, 2026, 10:13 PM EDT
Terminated Not applicable Interventional

Determination of Upper Airway Collapsibility During Routine CPAP Titration

NCT02566278
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway collapsibility (Pcrit)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 15, 2026, 10:13 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP

NCT01939067
View directory record Official record
Conditions
Respiratory Distress, Lung Injury
Interventions
Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Hours to 72 Hours
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced Sep 15, 2026, 10:13 PM EDT
Recruiting Not applicable Interventional

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

NCT05156112
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
Interventions
Positive Airway Pressure Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional

Impact of Automated Education and Follow-up Mechanisms on Patient Engagement

NCT02279901
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Telemedicine Education, IVR
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Sep 15, 2026, 10:13 PM EDT
Active, not recruiting Early Phase 1 Interventional

Respiratory Transition Without Continuous Positive Airway Pressure

NCT07390812
View directory record Official record
Conditions
Mild Respiratory Distress
Interventions
Transition without Continuous Positive Airway Pressure (CPAP), CPAP
Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
37 Weeks to 41 Weeks
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Phase 4 Interventional Results available

Oxygen Versus PAP for Sleep Apnea in Heart Failure

NCT01807897
View directory record Official record
Conditions
Heart Failure, Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
West Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 15, 2026, 10:13 PM EDT
Withdrawn Not applicable Interventional

Effect of Treating Sleep Disorder Breathing in Patients With Resistant Hypertension

NCT00973531
View directory record Official record
Conditions
Sleep Apnea, Hypertension
Interventions
Autotitrating Positive Airway Pressure (APAP), Traditional Split Titration Polysomnogram
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Using Telemedicine to Improve Veteran Sleep Apnea Care

NCT01259440
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Video Teleconferencing Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2015 · Synced Sep 15, 2026, 10:13 PM EDT
Withdrawn Not applicable Interventional

Evaluating the Efficacy of CPAP Therapy for the Treatment of Fatty Liver

NCT01849081
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease
Interventions
CPAP, LIfestyle
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Phase 3 Interventional

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

NCT00665977
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 6, 2010 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional

Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease

NCT02034357
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Sep 15, 2026, 10:13 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Home-Use Impact and Effectiveness of Cloud 9

NCT02688335
View directory record Official record
Conditions
Snoring
Interventions
Cloud9
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2019 · Synced Sep 15, 2026, 10:13 PM EDT
Active, not recruiting Not applicable Interventional

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

NCT03487185
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult, Preeclampsia, Obstetrical Complications
Interventions
Continuous Positive Airway Pressure, Sleep Advice Control
Device · Other
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
14
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

NCT00880165
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure apparatus
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 15, 2026, 10:13 PM EDT
Enrolling by invitation Not applicable Interventional

Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

NCT07176117
View directory record Official record
Conditions
Respiratory Distress Syndrome (Neonatal), Surfactant
Interventions
Surfactant Administration Through Laryngeal or Supraglottic Airway (SALSA), Continuous Positive Airway Pressure (CPAP)
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
33 Weeks to 38 Weeks
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
3
States / cities
Chula Vista, California • La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 15, 2026, 10:13 PM EDT
Active, not recruiting Not applicable Interventional

Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).

NCT04372953
View directory record Official record
Conditions
Lung Injury, Preterm Birth
Interventions
Positive End-Expiratory Pressure (PEEP)
Procedure
Lead sponsor
Murdoch Childrens Research Institute
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
906 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
4
States / cities
Little Rock, Arkansas • San Diego, California • Indianapolis, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 15, 2026, 10:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

The Role of Oxidative Stress in the Cardiovascular Consequences of Sleep Apnea

NCT00701441
View directory record Official record
Conditions
Sleep Apnea
Interventions
Not listed
Lead sponsor
Rami Khayat
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 29, 2013 · Synced Sep 15, 2026, 10:13 PM EDT
Withdrawn Not applicable Interventional

Initiation of Auto-adjusting CPAP for Newly Diagnosed OSA in Hospitalized Patients

NCT01556464
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Auto-adjusting CPAP
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2018 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury

NCT01882257
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
Interventions
BiPAP, BiPAP/AVAPS (Phillips Respironics)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)

NCT02522442
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Auto BiLevel
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 15, 2026, 10:13 PM EDT
Completed Not applicable Interventional Results available

Comparative Outcomes Management With Electronic Data Technology (COMET) Study

NCT01461473
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Positive Airway Pressure (PAP), Oral Appliance (OA)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
4
States / cities
Redwood City, California • Boston, Massachusetts • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Sep 15, 2026, 10:13 PM EDT