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Showing 2713–2736 of 6,439 matching trials from the local directory fallback.
Conditions
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Nasopharyngeal Squamous Cell Carcinoma, Metastatic Oral Cavity Squamous Cell Carcinoma, Metastatic Oropharyngeal Squamous Cell Carcinoma, Metastatic Sinonasal Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Nasopharyngeal Squamous Cell Carcinoma, Recurrent Oral Cavity Squamous Cell Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Recurrent Sinonasal Squamous Cell Carcinoma, Squamous Cell Carcinoma of Unknown Primary, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Nasopharyngeal Carcinoma AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Sinonasal Cancer AJCC v8
Interventions
Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resonance Imaging, Pembrolizumab, Positron Emission Tomography, Surgical Procedure
Biological · Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Conditions
Cancer
Interventions
Existing patient instructions, Modernized patient instructions
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Autoimmune Diseases, Cancer
Interventions
Fertility-Based Labwork, Infectious Disease Labwork
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 39 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Diabetes Mellitus, Type 1
Interventions
Placebo, Semaglutide Pen Injector
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 49 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Conditions
Anxiety Disorders, Borderline Personality Disorder, Eating Disorders, Emotion Dysregulation, Emotion Regulation, Emotional Distress, Emotional Dysfunction, Emotional Impulsivity, Emotional Instability, Emotional Maladjustment, Impulse Control Disorder, Mood Disorders, OCD, Obsessive-Compulsive Disorder, Stress Disorder
Interventions
Cognitive Restructuring, Emotional Awareness Training, Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation
Behavioral · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Novel Coding Strategies for Children With Cochlear Implants

NCT05203302
Conditions
Deafness
Interventions
Electric-only spectral resolution, Modulation Detection Threshold (MDT) and Gap Detection Tasks, Single-Electrode Pulse Train, Sound coding strategy.
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
6 Years to 80 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Advanced Cancer, Advanced Solid Tumor, Behavior Disorders, Cancer, Mental Health Issue
Interventions
Drug-Drug Interaction Profile, Drug-Gene Interaction Profile, Standard of Care
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Malignant Brain Glioma
Interventions
Magnetic Resonance Spectroscopic Imaging, Proton Therapy
Procedure · Device
Lead sponsor
Emory University
Other
Eligibility
Up to 21 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
Anal Cancer, Cervical Cancer, HPV-Related Anal Squamous Cell Carcinoma, HPV-Related Carcinoma, HPV-Related Cervical Carcinoma, Uterine Cervical Cancer
Interventions
Blood Sample Collection, HPV Genotyping (HPV DNA Test), Physical Exam, Positron Emission Tomography Scan (PET Scan)/ Computed Tomography Scan (CT Scan), Radiation Treatment With or Without Chemotherapy, Testing Archival Tumor Tissue
Other · Diagnostic Test · Radiation
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
Chicago, Illinois
Conditions
Chronic Pain, Opioid-use Disorder
Interventions
Active Comparator: Active tDCS + Active TUS, Sham Comparator: Sham tDCS + Sham TUS
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 85 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Hinsdale, Illinois • Cambridge, Massachusetts • Cleveland, Ohio
Conditions
Birth Defect, Brugada Syndrome, Congenital Heart Disease, Fetal Arrhythmia, Fetal Cardiac Anomaly, Fetal Cardiac Disorder, Fetal Death, Fetal Demise, Fetal Hydrops, Fetal Tachycardia, Gastroschisis, High Risk Pregnancy, Intrauterine Fetal Death, Long QT Syndrome, Pregnancy Loss, Stillbirth, Sudden Infant Death, Twin Monochorionic Monoamniotic Placenta, Twin Twin Transfusion Syndrome
Interventions
Fetal Magnetocardiogram and Neonatal Electrocardiogram, Substudy only: Maternal/Infant Pharmacogenomic assessment postnatally
Diagnostic Test · Genetic
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Recruiting No phase listed Observational Accepts healthy volunteers

Physical Activity and Cognitive Development in Children

NCT02542683
Conditions
Children, Congenital Heart Diseases
Interventions
structured physical activity program
Other
Lead sponsor
Columbia University
Other
Eligibility
30 Months to 6 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Malignant Glioma
Interventions
Biospecimen Collection, Magnetic Resonance Imaging, T2 (Observed)-Weighted Imaging
Procedure
Lead sponsor
John M. Buatti
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Recruiting Not applicable Interventional

ACT With CF Self-Help Toolkit

NCT07436351
Conditions
Cystic Fibrosis (CF), Depressive and Anxiety Disorders, Psychological Flexibility
Interventions
ACT with CF Self-Help Toolkit, Waitlist
Behavioral · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Recurrent Transformed B-Cell Non-Hodgkin Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Recurrent Transformed Non-Hodgkin Lymphoma, Refractory Transformed, Refractory Transformed B-cell Non-Hodgkin Lymphoma, Refractory Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Non-Hodgkin Lymphoma, Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma
Interventions
Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide, Fludarabine, Leukapheresis, Lisocabtagene Maraleucel, Lymph Node Biopsy, Positron Emission Tomography, Zanubrutinib
Procedure · Drug · Biological
Lead sponsor
Aseel Alsouqi
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
New York, New York • Columbus, Ohio • Salt Lake City, Utah
Conditions
Primary Central Nervous System Lymphoma, Refractory Cancer, Relapsed Cancer, Secondary Central Nervous System Lymphoma
Interventions
Autologous Stem Cell Transplant (ASCT), Pemetrexed, Whole Brain Radiation Therapy (WBRT), Zanubrutinib
Procedure · Drug · Radiation
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
1
States / cities
Miami, Florida
Conditions
HIV Prevention, HIV Treatment
Interventions
At Home Self-Collections
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Bipolar Depression, Bipolar Disorder, Major Depression, Major Depressive Disorder, Major Depressive Episode, Obsessive-Compulsive Disorder, Treatment Resistant Depression
Interventions
Deep Transcranial Magnetic Stimulation (dTMS), Electroconvulsive Therapy (ECT), Esketamine, Ketamine, Transcranial Magnetic Stimulation (TMS)
Device · Drug
Lead sponsor
Mark Niciu
Other
Eligibility
18 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2050
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Digestive System Neuroendocrine Tumor, Unresectable Digestive System Neuroendocrine Neoplasm, Unresectable Digestive System Neuroendocrine Tumor G1, Unresectable Digestive System Neuroendocrine Tumor G2
Interventions
Computed Tomography, Gallium Ga 68-DOTATATE, Lutetium Lu 177 Dotatate, Magnetic Resonance Imaging, Positron Emission Tomography, Questionnaire Administration, Stereotactic Body Radiation Therapy
Procedure · Radiation · Drug + 1 more
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Recruiting No phase listed Observational Accepts healthy volunteers

Dysbiosis & Long COVID

NCT06825819
Conditions
COVID-19
Interventions
Subjects with and without Long COVID
Biological
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Community Acquired Pneumonia in Children
Interventions
Amoxicillin, Amoxicillin-clavulanate, Ampicillin / Sulbactam Injection, Ampicillin for Injection, Cefprozil, Ceftriaxone for Injection, Clindamycin, Levofloxacin
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
3 Months to 18 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
HER2-positive Breast Cancer
Interventions
HER-2 pulsed DC1, Paclitaxel, Pertuzumab, Resection surgery, Trastuzumab
Biological · Drug · Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Prostate Cancer, Recurrent Prostate Cancer
Interventions
F-DCFPyL Injection, PSMA PET
Drug · Diagnostic Test
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Tampa, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation to the Hippocampus in Schizophrenia

NCT07010614
Conditions
Mental Disorder, Psychotic Disorder, Schizophrenia Disorders
Interventions
Intracranial electrodes, TMS, TMS sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California