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Showing 865–888 of 6,384 matching trials from the local directory fallback.
Conditions
Endometrial Cancer, Platinum-resistant Ovarian Cancer, Testicular Cancer
Interventions
CTIM-76
Drug
Lead sponsor
Context Therapeutics Inc.
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
14
States / cities
Little Rock, Arkansas • Beverly Hills, California • Denver, Colorado + 11 more
Conditions
Parkinson Disease
Interventions
Clinical DBS Setting, DBS Setting Maximizing Prefrontal Activation, DBS Setting Minimizing Prefrontal Activation, Levodopa, Sham DBS
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
45 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Conditions
Esophageal Diseases
Interventions
CEI Extra-Thoracic Subdermal Surgical Implantation - Cellspan™ Esophageal Implant-Adult (CEI) in patients that have had a previous partial esophagectomy, CEI Thoracic Surgical Implantation-Cellspan™ Esophageal Implant-Adult (CEI) in patients requiring a full reconstruction of the esophagus
Combination Product
Lead sponsor
Harvard Apparatus Regenerative Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
3
States / cities
Los Angeles, California • Ann Arbor, Michigan • Rochester, Minnesota
Conditions
Metastatic Pancreatic Neuroendocrine Tumor, Pancreatic Neoplasm, Stage III Pancreatic Neuroendocrine Tumor AJCC v8, Stage IV Pancreatic Neuroendocrine Tumor AJCC v8, Unresectable Pancreatic Neuroendocrine Tumor
Interventions
Biospecimen Collection, Computed Tomography, Lutetium Lu 177 Dotatate, Magnetic Resonance Imaging, Positron Emission Tomography, Sunitinib Malate
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
9
States / cities
Duarte, California • Irvine, California • Orange, California + 4 more
Recruiting Not applicable Interventional

Cardiometabolic Screening Program

NCT05386719
Conditions
Breast Cancer, Early-stage Breast Cancer
Interventions
Assess 10 year risk of cardiovascular event, Baseline, Follow-Up, Interpret BMI, Interpret HbA1c, Interpret lipid panel and assess other risk factors, Prescreening, Recommendations, Screening and Enrollment
Behavioral · Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast Carcinoma
Interventions
Biospecimen Collection, Chemotherapy, Questionnaire Administration, Short-Term Fasting
Procedure · Drug · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
5
States / cities
Cherry Hill, New Jersey • Sewell, New Jersey • Philadelphia, Pennsylvania + 1 more
Conditions
Arthropathy, Osteoarthritis, Tendinopathy
Interventions
Ketorolac injection to the shoulder, elbow, wrist, or hand, Triamcinolone injection to the shoulder, elbow, wrist, or hand
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Atlanta, Georgia
Recruiting Not applicable Interventional Accepts healthy volunteers

Anti-mullerian Hormone Levels in Healthy Females

NCT04537390
Conditions
Healthy
Interventions
Blood sample collection
Diagnostic Test
Lead sponsor
Erin Rowell
Other
Eligibility
Up to 18 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional

Amygdala-Prefrontal in Fear Extinction

NCT07800455
Conditions
Fear Extinction
Interventions
Direct intracranial electrical stimulation, Fear conditioning
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Esophagus Cancer, Gastro-esophageal Junction (GEJ) Cancer
Interventions
FLOT (Fluorouracil+Leucovorin+Oxaliplatin+Docetaxel)(D), PULSAR- Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy
Drug · Radiation
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Diabetic Foot Ulcer (DFU), Granulation of Chronic Diabetic Wounds
Interventions
Standard of Care of Diabetic Foot Ulcers, an allogenic cell-based product, containing living human bone marrow-derived mesenchymal stem cells (MSCs) and MSCs differentiated into adipocytes on a porous chitosan-gelatin matrix
Other · Drug
Lead sponsor
Ayu, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Rectal Adenocarcinoma, Rectal Cancer
Interventions
High Rare Dose Rectal Brachytherapy Boost
Radiation
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Aurora, Colorado • Rochester, New York • Portland, Oregon
Recruiting Not applicable Interventional

CARE-D-FOOT-Nav Pilot

NCT07143175
Conditions
Diabetic Foot Ulcer (DFU)
Interventions
Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Atlanta, Georgia • Decatur, Georgia
Conditions
Breast Cancer
Interventions
Moderately Hypofractionated Radiation, Ultrahypofractionated Radiation
Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
768 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
5
States / cities
Loveland, Colorado • Jacksonville, Florida • Voorhees Township, New Jersey + 2 more
Conditions
Anal Cancer, Bladder Cancer, Breast Cancer, Cervix Cancer, Colon Cancer, Gastric Cancer, Head and Neck Cancer, Liver Cancer, Lung Cancer, Rectal Cancer, Sarcoma, Uterine Cancer
Interventions
ETHOS 2.0, HyperSight cone beam computed tomography (CBCT) scan
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Relapsing Remitting Multiple Sclerosis
Interventions
Active stimulation, Disease-Modifying Therapies (DMTs), Implant Procedure, Non-active stimulation
Device · Drug · Procedure
Lead sponsor
SetPoint Medical Corporation
Industry
Eligibility
22 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
9
States / cities
Irvine, California • Atlanta, Georgia • Baltimore, Maryland + 6 more
Conditions
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC), Stage II Renal Pelvis Cancer AJCC v8, Stage III Renal Pelvis Cancer AJCC v8
Interventions
Biopsy, Biospecimen Collection, Computed Tomography, MRI, Pembrolizumab, Questionnaire Administration, Tivozanib
Procedure · Biological · Other + 1 more
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
1,040 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2037
U.S. locations
425
States / cities
Phoenix, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 339 more
Recruiting No phase listed Observational Accepts healthy volunteers

Assessing Brain Metabolism Using MRS With Deuterated Glucose

NCT06594315
Conditions
Glioma
Interventions
Blood Sample, Deuterated Glucose, MR spectroscopy (MRS), Magnetic Resonance Imaging (MRI)
Procedure · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Francisco, California
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Communication Intervention, Coordination, Educational Intervention, Electronic Health Record Review, Informational Intervention, Interview, Patient Navigation, Referral, Text Message-Based Navigation Intervention
Other · Behavioral
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California
Conditions
Alcohol Use Disorder
Interventions
Inactive Placebo, Psilocybin, Supportive therapy sessions
Other · Drug · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 1Phase 2 Interventional

Lurbinectedin in FET-Fused Tumors

NCT05918640
Conditions
Desmoplastic Small Round Cell Tumor, Ewing Sarcoma, Pediatric Cancer, Undifferentiated Sarcoma
Interventions
Lurbinectedin
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
Los Angeles, California • Iowa City, Iowa • Boston, Massachusetts + 3 more
Conditions
Breast Cancer
Interventions
Adjuvant Chemotherapy + Ovarian Function Suppression, Ovarian Function Suppression + Aromatase Inhibitor
Drug
Lead sponsor
NRG Oncology
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
3,960 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
1226
States / cities
Birmingham, Alabama • Anchorage, Alaska • Fairbanks, Alaska + 809 more
Conditions
PARKINSON DISEASE (Disorder)
Interventions
Continuous DBS (cDBS) - Active Control (Medtronic Percept™), aDBS-Extended (Medtronic Percept™), aDBS-Standard (Medtronic Percept™)
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Davis, California
Conditions
Borderline Resectable/Unresectable Pancreatic Cancer, Non Metastatic Pancreatic Cancer
Interventions
Intratumoral MMR Injection
Biological
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Little Rock, Arkansas