Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 1, 2026, 8:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cognitive Performance, Attention, Reaction Time, Caffeine
Interventions
Caffeinated Coffee, Decaffeinated Coffee Placebo
Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Caffeinated Coffee on Intraocular Pressure

NCT01364207
Conditions
Primary Open Angle Glaucoma
Interventions
Caffeinated Coffee, Decaffeinated Coffee
Other
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
40 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Clinical Effect of Caffeine Consumption in Patients Taking Oral Terbinafine

NCT05667246
Conditions
Terbinafine Adverse Reaction
Interventions
Caffeinated Coffee, Decaffeinated Coffee
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Postoperative Ileus
Interventions
Coffee, Water
Dietary Supplement · Other
Lead sponsor
Mount Carmel Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Breast Reconstruction, Deep Inferior Epigastric Perforator, Microvascular Free Flap Transfer
Interventions
Caffeinated Coffee, DecaffeinatedCoffee
Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Phase 1 Interventional Accepts healthy volunteers

Reference Values for Plasma Catechols

NCT00267904
Conditions
Healthy Volunteers, Normal Physiology
Interventions
Coffee, Banana, Olives, Temp. manip.
Other
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Postoperative Ileus
Interventions
caffeinated coffee
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Worcester, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of High Caffeine Content Coffee on Blood Pressure in Young Adults

NCT04060225
Conditions
High Blood Pressure
Interventions
Coffee
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 30 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Rochester, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Thermogenenic Responses to Fasting and Overfeeding in Women

NCT06610162
Conditions
Obesity
Interventions
Eucalaloric feeding, Acute Fasting, Acute Overfeeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Atrial Fibrillation, Coffee
Interventions
Consume coffee, Avoid coffee
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Pharyngitis
Interventions
placebo, flurbiprofen, acetaminophen 650mg
Drug
Lead sponsor
Reckitt Benckiser LLC
Industry
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of Coffee on Glucose Metabolism

NCT00950898
Conditions
Type 2 Diabetes
Interventions
decaff, caffcoff, caffeine, placebo
Other
Lead sponsor
Brooklyn College of the City University of New York
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Overweight
Interventions
Decaffeinated coffee, Caffeinated coffee, No coffee
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts