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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Caffeine reduction Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Reducing the Unnecessary Use of Heavily Marketed Medications: A Randomized Controlled Trial

NCT00788346
View directory record Official record
Conditions
Use of Sleep Medications
Interventions
Computerized alerts, Alerts Plus Detailing
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
Not listed
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2012 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional

Defeating Urinary Incontinence With Exercise Training (DUET) Feasibility Study

NCT02206958
View directory record Official record
Conditions
Toileting Disability, Functional Urinary Incontinence
Interventions
Defeating Urinary Incontinence with Exercise Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
60 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2019 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Results available

Sleep Disruption in New Mothers: An Intervention Trial

NCT01321710
View directory record Official record
Conditions
Pregnancy, Postpartum Period, Sleep Disturbance
Interventions
Sleep hygiene, Dietary information, Acetaminophen
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2012 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CBT-I on Alcohol Treatment Outcomes Among Veterans

NCT03806491
View directory record Official record
Conditions
Insomnia, Alcohol Use Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Phase 2 Interventional

Behavioral Sleep Intervention in Adult Family Homes

NCT00393627
View directory record Official record
Conditions
Dementia
Interventions
Sleep Education Program
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Thrive With Type 1 Diabetes 2026

NCT07522866
View directory record Official record
Conditions
Type1diabetes
Interventions
TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm
Behavioral
Lead sponsor
Emory University
Other
Eligibility
31 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional

The Effectiveness of Email Alerting on Reducing Employees' Unauthorized Access to Protected Health Information

NCT05251844
View directory record Official record
Conditions
Unauthorized Data Access
Interventions
receiving an email
Other
Lead sponsor
Protenus, Inc.
Industry
Eligibility
Not listed
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2022 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional

Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care

NCT05990296
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction
Interventions
Multiprong CDS with referral to pharmacist co-management, Multiprong CDS with GDMT order set, Focused education
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
4,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional

Treatment for Caffeine Dependence

NCT01951872
View directory record Official record
Conditions
Caffeine Use Disorder (DSM-5 Condition for Further Study)
Interventions
Manual-based treatment for caffeine dependence
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Sep 7, 2026, 9:51 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE ©," AMONG COLLEGE STUDENTS

NCT07434921
View directory record Official record
Conditions
Drowsiness, Sleep Deprivation, Fatigue
Interventions
MTM Theory based intervention, Standard AAA Knowledge based
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 7, 2026, 9:51 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Caffeine Reduction and Overactive Bladder Symptoms

NCT00754260
View directory record Official record
Conditions
Overactive Bladder
Interventions
Caffeine reduction
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Sugar-sweetened Beverage Consumption Among Children

NCT04025060
View directory record Official record
Conditions
Pediatric Obesity, Diet, Food, and Nutrition
Interventions
Commercially-available caffeine-free soda, Carbonated water, Regular soda
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
8 Years to 11 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)

NCT00393874
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders, Insomnia, Nightmares
Interventions
Behavioral Sleep Intervention, Prazosin, Placebo
Behavioral · Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2016 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting Not applicable Interventional

REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam

NCT02880163
View directory record Official record
Conditions
Hemorrhagic Shock, Trauma, Exsanguinating Hemorrhage, Shock; Traumatic
Interventions
ResQFoam
Device
Lead sponsor
Arsenal Medical, Inc.
Industry
Eligibility
15 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional

Fluids Affecting Bladder Urgency and Lower Urinary Symptoms

NCT03625492
View directory record Official record
Conditions
Overactive Bladder, Urinary Urgency, Urinary Bladder, Overactive, Urinary Incontinence, Urge, Caffeine, Alcohol Drinking, Lower Urinary Tract Symptoms
Interventions
Reducing Potentially Irritating Beverages, Adopting the USDA Healthy Eating Habits
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance

NCT00108628
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Imagery Rehearsal, Sleep and Nightmare Management
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2015 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Remote Guided Caffeine Reduction

NCT04560595
View directory record Official record
Conditions
Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction, Sleep Initiation and Maintenance Disorders, Caffeine; Sleep Disorder, Caffeine, Caffeine-Induced Anxiety Disorder, Caffeine Withdrawal, Caffeine-Induced Sleep Disorder, Without Use Disorder, Caffeine Abuse, Insomnia, Anxiety Disorders, Sleep Disorder, Heartburn, Diarrhea
Interventions
Caffeine Reduction Manual
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting Not applicable Interventional

Role of Sleep Reactivity in Shift Work Disorder

NCT05424406
View directory record Official record
Conditions
Shift-work Disorder
Interventions
Active phototherapy, Control phototherapy, Cognitive Behavioral Therapy (CBT), Sleep education control
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Sleep Health in U.S. Marines

NCT07420205
View directory record Official record
Conditions
Depression, Suicidality, Sleep
Interventions
Sleep Leadership, Circadian, Light, and Sleep Skills in Shipboard Military (CLASS-MC) Personnel Program, Insomnia Coach
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
860 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Caffeine Reduction on Snoring and Quality of Life

NCT00641810
View directory record Official record
Conditions
Snoring
Interventions
Caffeine reduction
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 30, 2013 · Synced Sep 7, 2026, 9:51 PM EDT
Active, not recruiting Not applicable Interventional

Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms.

NCT06737432
View directory record Official record
Conditions
Ventilation, ARDS, Respiratory Failure, Mechanical Ventilation, Ventilator-induced Lung Injury (VILI), Quality Improvement, Ventilator Associated Events
Interventions
RKP Monitoring Software
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 100 Years
Enrollment
875 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 7, 2026, 9:51 PM EDT
Recruiting No phase listed Observational

AngelMed Guardian® System PMA Post Approval Study

NCT05412927
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
PMA P150009 AngelMed Guardian® System
Device
Lead sponsor
Angel Medical Systems
Industry
Eligibility
21 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
18
States / cities
Glendale, Arizona • Mesa, Arizona • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 7, 2026, 9:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Expectancy Challenges to Prevent Nonmedical Prescription Stimulant Use

NCT03648684
View directory record Official record
Conditions
Prescription Drug Abuse (Not Dependent)
Interventions
Caffeine-Based Expectancy Challenge, Placebo-Based Expectancy Challenge
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 25 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 7, 2026, 9:51 PM EDT