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Showing 1–24 of 347 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Calorie Restricted Diet Clear all
Recruiting Not applicable Interventional

Healthy Lifestyles in Bipolar Disorder: Bay Area Study

NCT06555406
View directory record Official record
Conditions
Bipolar Disorder, Time Restricted Eating
Interventions
Time-restricted eating for 8 weeks
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional

The Medically Reproducing Bariatric Surgery (MRB) II Study

NCT06363747
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Very Low Calorie Diet
Other
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
25 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 3, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

NCT06836479
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes
Interventions
NOURISH Diet, Self-Selected Diet (Control)
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional

PACE-PC: Primary Care Management of Adolescent Obesity

NCT00415974
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Physician Counseling, Health Educator, Phone Counseling, Health promotion materials on physical activity and nutrition
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
11 Years to 13 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Health at Every Size vs a Behavioral Weight Loss Approach for Obese Women

NCT00769717
View directory record Official record
Conditions
Obesity
Interventions
Wellness-Centered (HUGS), Weight-Centered (LEARN)
Behavioral
Lead sponsor
The Reading Hospital and Medical Center
Other
Eligibility
30 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
West Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Sep 3, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty

NCT04599010
View directory record Official record
Conditions
Body Composition, Feeding; Difficult, Newborn, Nutrition Disorder, Infant
Interventions
Dietary intervention
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Week to 10 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Orlando, Florida • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Intervention in Depression

NCT06080932
View directory record Official record
Conditions
Depression, Ketosis
Interventions
Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults

NCT00381290
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diet, Exercise
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
55 Years and older
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure

NCT00939640
View directory record Official record
Conditions
Diastolic Heart Failure, Hypertensive Heart Disease
Interventions
DASH/sodium-restricted diet (SRD)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Giving a Low Carbohydrate Diet to Overcome Hypertension

NCT04230928
View directory record Official record
Conditions
Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
Interventions
Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
Other · Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Recruiting Not applicable Interventional

Feasibility and Acceptibility of a Multi-site Trial of Time Restircted Eating During Chemotheraply for Breast Cancer.

NCT07387445
View directory record Official record
Conditions
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Neoplasm Female, Breast Cancer
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
25 Years to 99 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional

A Phase II Study of the Effect of a Low Calorie Diet on Patients Undergoing Liver Resection

NCT01645852
View directory record Official record
Conditions
Nonalcoholic Fatty Liver Disease, Hepatic Steatosis, Steatohepatitis
Interventions
Optifast 800
Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Worcester, Massachusetts • Lebanon, New Hampshire • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Sep 3, 2026, 1:02 PM EDT
Active, not recruiting Phase 3 Interventional

Breast Cancer WEight Loss Study (BWEL Study)

NCT02750826
View directory record Official record
Conditions
Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Synchronous Bilateral Breast Carcinoma
Interventions
Health Education Program, Weight Loss Intervention
Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
3,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1464
States / cities
Daphne, Alabama • Mobile, Alabama • Anchorage, Alaska + 921 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Dietary Intervention on Insulin Requirements in Type 1 Diabetes

NCT04944316
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Dietary intervention
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 3, 2026, 1:02 PM EDT
Active, not recruiting Not applicable Interventional

Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

NCT04861571
View directory record Official record
Conditions
NAFLD
Interventions
Dietary intervention with very low calorie diet (VLCD), Control Arm
Dietary Supplement · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional

CAREFOR: Precision Medicine Driving Precision Nutrition for the Treatment of NeoAdjuvant Breast Cancer

NCT02827370
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Behavioral Dietary Intervention
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00427193
View directory record Official record
Conditions
Aging
Interventions
Caloric Restriction (CR), Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 50 Years
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Results available

Delish Study: Diabetes Education to Lower Insulin, Sugars, and Hunger

NCT03207711
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Carbohydrate-restricted diet, Mindfulness
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Exercise and Protein During Weight Loss

NCT03600311
View directory record Official record
Conditions
Weight Loss, Starvation
Interventions
Caloric Restriction, Post-Exercise Protein, Energy Balance, Post-Exercise Carbohydrate, Calcium and Vitamin D
Other · Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 30 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Sep 3, 2026, 1:02 PM EDT
Terminated Phase 3 Interventional

A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients

NCT00483171
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
Drug · Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2012 · Synced Sep 3, 2026, 1:02 PM EDT
Not yet recruiting Not applicable Interventional

Safety and Tolerability of a Nutritional Formula Designed to Aid in Maintenance of Muscle During Periods of Caloric Restriction in Adults

NCT07447843
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Redefine, Placebo
Dietary Supplement
Lead sponsor
Nature's Sunshine Products, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 3, 2026, 1:02 PM EDT
Not listed Not applicable Interventional

Dietary Sodium-Restriction (DIS) and Renal Meals (RM) for Hemodialysis (HD)(DISaRM-HD)

NCT04991441
View directory record Official record
Conditions
Kidney Failure, Chronic, Dietary Modification
Interventions
Controlled Dietary Sodium Restriction, Control Diet & Controlled Dietary Sodium Restriction
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 3, 2026, 1:02 PM EDT
Completed Not applicable Interventional

Weight Loss-Independent Metabolic Effects of Roux-En-Y Gastric Bypass in Diabetes

NCT02207777
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Roux-en-Y gastric bypass surgery, Low-calorie diet
Procedure · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 3, 2026, 1:02 PM EDT
Not listed No phase listed Observational

Impact of Life-Style Modification On Ablation Outcome in Atrial Fibrillation

NCT02219841
View directory record Official record
Conditions
Atrial Fibrillation, Obesity
Interventions
radiofrequency catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 3, 2026, 1:02 PM EDT