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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:57 AM EST

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Carbohydrate restricted dietary intervention Clear all

Conditions: Alzheimer Disease
Interventions: Ketogenic Diet, Therapeutic Lifestyles Changes Diet; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 50 Years to 90 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Fairway, Kansas

Conditions: Hypertension
Interventions: Dietitian-Assisted DASH groceries, Self-directed shopping; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bladder Cancer, Diabetes Mellitus
Interventions: CR diet, Exercise; Other · Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Kansas City, Kansas

Conditions: Overweight, Obesity and Other Hyperalimentation (E65-E68)
Interventions: Berry fruit powder OR nutritional ketosis, Placebo powder OR higher carbohydrate; Dietary Supplement
Lead sponsor: University of Cincinnati; Other
Eligibility: 50 Years to 65 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Diabetes Mellitus, Type 2
Interventions: Dietary intervention; Behavioral
Lead sponsor: Physicians Committee for Responsible Medicine; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging, Alcohol Drinking
Interventions: Ketone Supplement, Control Diet, Ketogenic diet, Ethanol; Dietary Supplement · Other · Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 50 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hypercholesterolemia and Hyperlipidemia
Interventions: Ketogenic Diet, Control Diet; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 39 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Ketogenic Dieting
Interventions: Carbohydrate Supplement (Carb10), Diet, Exercise; Dietary Supplement · Other
Lead sponsor: Texas Woman's University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Denton, Texas

Conditions: Rheumatoid Arthritis, Inflammation, Obesity, Ketogenic Dieting, Metabolic Syndrome
Interventions: Ketogenic diet; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 65 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Insulin Sensitivity
Interventions: Sevelamer, Synbiotic, Maltodextrin, High Fat diet, Low Fat diet; Drug · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Obesity
Interventions: Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss; Behavioral
Lead sponsor: Coastal Carolina University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Conway, South Carolina

Conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis
Interventions: Specific Carbohydrate Diet (SCD), Modified Specific Carbohydrate Diet (MSCD); Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 7 Years to 18 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 20
States / cities: Little Rock, Arkansas • Los Angeles, California • Oakland, California + 17 more

Conditions: Bipolar Depression
Interventions: Ketogenic Diet; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Type 2 Diabetes Mellitus
Interventions: Carbohydrate-restricted diet, Mindfuless; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Polycystic Kidney Disease
Interventions: Ketogenic Diet, Ketone/Glucose Monitoring, CGM/CKM, Blood Draw, Body Composition, Change in glomerular filtration rate (mg/mmol) via magnetic resonance imaging (MRI) .; Other · Biological
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Pediatric Obesity
Interventions: Energy Restriction, Higher protein, Lower Protein; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 12 Years to 17 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Elevated Blood Pressure, Hypertension
Interventions: Dietitian-Assisted DASH groceries, Self-directed shopping; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obesity
Interventions: Egg-based diet (EBD), Carbohydrate-based diet (CBD); Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 60 Years to 75 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Type 1 Diabetes
Interventions: Low carbohydrate diet; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 5 Years to 11 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: PCOS (Polycystic Ovary Syndrome)
Interventions: Ketogenic diet, Exogenous Ketone Supplement; Other · Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: Ketogenic diet, Low-fat Mixed diet; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Non-alcoholic Fatty Liver Disease, Childhood Obesity, Insulin Resistance
Interventions: Carbohydrate-restricted diet, Control, low-fat diet; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 9 Years to 17 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Ventral Hernia, Panniculus, Abdominoplasty, Flap Reconstruction
Interventions: Prehabilitation Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 19 Years and older
Enrollment: 520 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: San Jose, California • Stanford, California

Conditions: Depression, Ketosis
Interventions: Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID; Other · Biological · Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Search by objective public record fields.

Therapeutic Diets in Alzheimer's Disease

Groceries for Black Residents of Boston to Stop Hypertension Among Adults With Treated Hypertension

The Feasibility of a Diet and Exercise Intervention in Diabetics During Treatment for Non-muscle Invasive Bladder Cancer

Early Intervention in Cognitive Aging

Effect of a Dietary Intervention on Intracellular Lipid Levels, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes

Effect of Nutritional Ketosis on Alcohol Metabolism

Mechanism of Ketogenic Diet-Induced Hypercholesterolemia

Determining the Ergogenic Effects of Carb10™ Supplementation on Carbohydrate-Rich and Carbohydrate-Restricted Diets

Ketogenic Diet in Rheumatoid Arthritis (RA)

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los

Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease

Ketogenic Intervention for Bipolar Depression

(R33 Phase) DELISH Study: Diabetes Education to Lower Insulin, Sugars, and Hunger

Well-Formulated Ketogenic Diet Polycystic Kidney Disease

PrOtein and WEight Loss in teenageRs

Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension

Egg Diet to Improve Metabolic Health and Function

Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes

Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot

Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity

Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures

Ketogenic Intervention in Depression