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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Carbon dioxide Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Sibling Oocyte Study- Comparison of ZyMotTM Microfluidics Device to Density Gradient for Sperm Selection During ICSI

NCT04818593
View directory record Official record
Conditions
ART
Interventions
ZyMot Multi Sperm Separation Device (850 ul), Density Gradient Centrifugation
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 24, 2026, 1:17 AM EDT
Terminated Not applicable Interventional

Acute Lung Injury Ventilator Evaluation (ALIVE)

NCT01901354
View directory record Official record
Conditions
Acute Lung Injury, Adult Respiratory Distress Syndrome
Interventions
Low-tidal-volume ventilation, Airway Pressure Release Ventilation (APRV)
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Not applicable Interventional

A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT00685386
View directory record Official record
Conditions
Cholestasis
Interventions
CO2 insufflation, Room air insufflation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Sep 24, 2026, 1:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Lavage and Suction of the Right Upper Quadrant to Reduce Post Laparoscopic Shoulder Pain

NCT02004470
View directory record Official record
Conditions
Shoulder Pain
Interventions
Active lavage and suction
Procedure
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
4
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2014 · Synced Sep 24, 2026, 1:17 AM EDT
Recruiting Not applicable Interventional

SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

NCT03737786
View directory record Official record
Conditions
Acute Stroke
Interventions
Tight control of end-tidal CO2 levels
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 110 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Breath Analysis Technique to Diagnose Pulmonary Embolism

NCT00368836
View directory record Official record
Conditions
Pulmonary Embolism
Interventions
BreathScreen PE
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Sep 24, 2026, 1:17 AM EDT
Terminated Not applicable Interventional

Functional Magnetic Resonance Imaging (fMRI) Vascular Reactivity in Cerebral Cavernous Malformations (CCM)

NCT05298709
View directory record Official record
Conditions
Cerebral Cavernous Malformation
Interventions
Hyperventilation and CO2 challenge
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 24, 2026, 1:17 AM EDT
Recruiting Not applicable Interventional

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

NCT05351827
View directory record Official record
Conditions
Spinal Cord Injuries, Autonomic Dysreflexia
Interventions
Mild Intermittent Hypoxia, Sham
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Terminated Not applicable Interventional Results available

Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure

NCT00594009
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Venovenous CO2 Removal (VVCO2R) in COPD
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Sep 24, 2026, 1:17 AM EDT
Recruiting Not applicable Interventional

Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD

NCT07674264
View directory record Official record
Conditions
Parkinson Disease, Parkinsonism
Interventions
Acute intermittent hypercapnic hypoxia (AIHH), Acute intermittent hypercapnic normoxia (AIHN)
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1

NCT01925482
View directory record Official record
Conditions
Middle Ear Gas Exchange
Interventions
6%CO2, 25%O2, balance N2, 6% CO2, 0%O2, balance N2, 20%CO2, 6%O2, balance N2, 0%CO2, 6%O2, balance N2, 6% CO2, 6%O2, balance N2, 6%CO2, 6%O2, 0%N2, balance argon
Drug
Lead sponsor
Cuneyt M. Alper
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser

NCT02357979
View directory record Official record
Conditions
Dental Caries
Interventions
Laser, Fluoride
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 24, 2026, 1:17 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

NCT06629090
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cerebrovascular Circulation
Interventions
MRI, Prazosin, Placebo
Device · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Not yet recruiting Not applicable Interventional

Intraoperative CO₂ (Carbon Dioxide)

NCT07592468
View directory record Official record
Conditions
Wound Edges
Interventions
CO2 Fractionated Laser, Non CO2 Laser Treatment
Device · Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Effects of CBD Products on Anxiety Among U.S. Women

NCT05108220
View directory record Official record
Conditions
Anxiety, Generalized Anxiety Disorder
Interventions
Cannabidiol (CBD)- containing consumer products
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
24 Years to 44 Years · Female only
Enrollment
1,350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 24, 2026, 1:17 AM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

NCT07210606
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Trazodone + PAP therapy, Oxygen + PAP therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Not applicable Interventional Results available

Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance

NCT02115646
View directory record Official record
Conditions
Burn Scars
Interventions
fractionated carbon dioxide laser
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
5 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Sep 24, 2026, 1:17 AM EDT
Terminated Not applicable Interventional

POMCO2 Clinical Study MicroTrend System pCO2 Sensor

NCT05499624
View directory record Official record
Conditions
Hypoperfusion
Interventions
MicroTrend System
Device
Lead sponsor
ExoStat Medical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Respiratory Dysregulation and Breathing Training in Anxious Outpatients

NCT00108277
View directory record Official record
Conditions
Anxiety
Interventions
Breathing Training-Raise CO2, Breathing Training- Lower CO2
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Phase 2 Interventional

Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia

NCT02473016
View directory record Official record
Conditions
Trigeminal Neuralgia
Interventions
Carbon Dioxide Drug Delivery System (CDDS)
Drug
Lead sponsor
Capnia, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Los Angeles, California • Tampa, Florida • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2017 · Synced Sep 24, 2026, 1:17 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type

NCT01688063
View directory record Official record
Conditions
Skin Scarring, Skin Elasticity
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Terminated Phase 2 Interventional Results available

Pilot Study Evaluating the Use of Nasal Carbon Dioxide for the Treatment of Cluster Headache

NCT02381795
View directory record Official record
Conditions
Cluster Headache
Interventions
Nasal Carbon Dioxide
Drug
Lead sponsor
Cady, Roger, M.D.
Individual
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Sep 24, 2026, 1:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Clinical Validation of Non-Contact Vital Signs

NCT07362641
View directory record Official record
Conditions
Vital Sign Evaluation
Interventions
SmartSpectra Vital Signs Monitor measurement
Device
Lead sponsor
Presage Technologies, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 24, 2026, 1:17 AM EDT
Completed Phase 2 Interventional Results available

Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated Calcinosis

NCT01572844
View directory record Official record
Conditions
Calcinosis
Interventions
Fractionated Carbon Dioxide (FCO2) Laser, Sodium thiosulfate
Device · Drug
Lead sponsor
Alison Ehrlich
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Sep 24, 2026, 1:17 AM EDT