Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Carboxyhemoglobin Clear all

Conditions: Carbon Monoxide Exposure
Interventions: Not listed
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Chronic Obstructive Pulmonary Disease, HIV, Emphysema
Interventions: blood draw, questionnaires, Lung function testing, Six-Minute walk test, Quantitative CT scans, Nasal secretion and cell collection, Echocardiogram; Procedure · Radiation
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 232 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Newborn, Birth, Preterm
Interventions: OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor; Device
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 29 Weeks and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 3
States / cities: Los Angeles, California • St Louis, Missouri • Winston-Salem, North Carolina

Conditions: Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
Interventions: knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years to 45 Years · Female only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Delayed Function of Renal Transplant
Interventions: SANGUINATE, Normal Saline; Drug
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 20
States / cities: Phoenix, Arizona • Los Angeles, California • San Diego, California + 15 more

Conditions: Renal Insufficiency, Chronic
Interventions: SANGUINATE; Biological
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Smoking, Cigarette
Interventions: Not listed
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 30 participants
Timeline: 2021
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Acute Respiratory Distress Syndrome, Sepsis
Interventions: Inhaled Carbon Monoxide at CFK equation-determined personalized dose (200-500 ppm to achieve a COHb level of 6-8%), Inhaled Medical air; Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 6
States / cities: Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 2 more

Conditions: Lung Diseases
Interventions: eCO testing; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Smoking, Smoking Cessation
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: New York, New York

Conditions: Cerebral Ischemia
Interventions: SANGUINATE™; Biological
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature, Infant, Low Birth Weight
Interventions: Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin; Diagnostic Test
Lead sponsor: Stanford University; Other
Eligibility: 24 Weeks to 34 Weeks
Enrollment: 143 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Stanford, California

Conditions: Healthy Volunteers
Interventions: Mespere Oximeter, Radiometer OSM-3 Co-Oximeter; Device
Lead sponsor: Mespere Lifesciences Inc.; Industry
Eligibility: 21 Years to 49 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Acute Anemia
Interventions: SANGUINATE™; Drug
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 32
States / cities: Birmingham, Alabama • Prescott, Arizona • Baldwin Park, California + 26 more

Conditions: Acute Ischemic Stroke
Interventions: PP-007 (Two doses administered 24±6 hours apart) + SOC (IVT or MT or IVT+MT); Biological
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 8
States / cities: Jacksonville, Florida • Miami, Florida • Atlanta, Georgia + 5 more

Conditions: ABO Incompatibility, Hemolytic Disease of Newborn, Neonatal Jaundice, Neonatal Hyperbilirubinemia
Interventions: Not listed
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: Up to 28 Days
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 2
States / cities: Syracuse, New York

Conditions: HIV, COPD, Pulmonary Disease, Aging
Interventions: PFT, lab work, 6MWT, questionnaires; Procedure · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Liver Cancer
Interventions: CO Testing Pre/Post Hepatic Resection, ABG Testing Pre/Post Hepatic Resection, CT Evaluations; Procedure · Diagnostic Test
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 1
States / cities: Glen Burnie, Maryland

Conditions: Anemia, Sickle Cell
Interventions: SANGUINATE, Placebo; Drug
Lead sponsor: Prolong Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 9
States / cities: Hollywood, Florida • Tampa, Florida • Baltimore, Maryland + 5 more

Conditions: Elevated Levels of Carboxyhemoglobin and Methemoglobin
Interventions: Elevated levels of carboxyhemoglobin; Other
Lead sponsor: Nonin Medical, Inc; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

End-Tidal Carbon Dioxide as a Measure of Carboxyhemoglobin in Carbon Monoxide Poisoning

Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes

Pulse Oximetry Performance Comparison in Newborns

Smoking Reduction In Gravid Substance Use Disorders

Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant

Study to Assess the Safety and Impact on Humoral Sensitization of SANGUINATE in Patients With End Stage Renal Disease

A Comparison of Exhaled Carbon Monoxide Measurements Using the iCOquit Smokerlyzer and Vitalograph Breath CO Monitor vs Carboxyhemoglobin From Venous Samples While Validating a Mobile Research Application

Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)

Exhaled Carbon Monoxide (eCO) for Diffusing Capacity (DLCO) Correction

Alternate Nicotine Delivery Systems and Airway Epithelial Biology

Safety and Effect of SANGUINATE™ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) Following Subarachnoid Hemorrhage (SAH)

Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants

Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin

A Phase 1 Safety Study of SANGUINATE™ In Patients With Acute Severe Anemia.

Safety Study of PP-007 in Subjects With Acute Ischemic Stroke

Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis

Translation Evaluation of Aging, Inflammation and HIV in Lung Function (TEAL)

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

Dysfunctional Hemoglobin