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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Completed No phase listed Observational Accepts healthy volunteers

Dysfunctional Hemoglobin

NCT02262195
Conditions
Elevated Levels of Carboxyhemoglobin and Methemoglobin
Interventions
Elevated levels of carboxyhemoglobin
Other
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 45 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Conditions
Liver Cancer
Interventions
CO Testing Pre/Post Hepatic Resection, ABG Testing Pre/Post Hepatic Resection, CT Evaluations
Procedure · Diagnostic Test
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Glen Burnie, Maryland
Conditions
Delayed Function of Renal Transplant
Interventions
SANGUINATE, Normal Saline
Drug
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
20
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 15 more
Conditions
HIV, COPD, Pulmonary Disease, Aging
Interventions
PFT, lab work, 6MWT, questionnaires
Procedure · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Smoking, Cigarette
Interventions
Not listed
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Timeline
2021
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Conditions
Acute Ischemic Stroke
Interventions
PP-007 (Two doses administered 24±6 hours apart) + SOC (IVT or MT or IVT+MT)
Biological
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Jacksonville, Florida • Miami, Florida • Atlanta, Georgia + 5 more
Conditions
Anemia, Sickle Cell
Interventions
SANGUINATE, Placebo
Drug
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
9
States / cities
Hollywood, Florida • Tampa, Florida • Baltimore, Maryland + 5 more
Conditions
Acute Anemia
Interventions
SANGUINATE™
Drug
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
32
States / cities
Birmingham, Alabama • Prescott, Arizona • Baldwin Park, California + 26 more
Conditions
Renal Insufficiency, Chronic
Interventions
SANGUINATE
Biological
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
ABO Incompatibility, Hemolytic Disease of Newborn, Neonatal Jaundice, Neonatal Hyperbilirubinemia
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
Up to 28 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Syracuse, New York
Completed Not applicable Interventional Accepts healthy volunteers

Exhaled Carbon Monoxide (eCO) for Diffusing Capacity (DLCO) Correction

NCT01126047
Conditions
Lung Diseases
Interventions
eCO testing
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
2
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking Reduction In Gravid Substance Use Disorders

NCT04132232
Conditions
Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
Interventions
knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Completed No phase listed Observational Accepts healthy volunteers

Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants

NCT02691156
Conditions
Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature, Infant, Low Birth Weight
Interventions
Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
24 Weeks to 34 Weeks
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Completed No phase listed Observational Accepts healthy volunteers

Pulse Oximetry Performance Comparison in Newborns

NCT06637917
Conditions
Newborn, Birth, Preterm
Interventions
OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
29 Weeks and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Los Angeles, California • St Louis, Missouri • Winston-Salem, North Carolina
Terminated No phase listed Observational Accepts healthy volunteers

Alternate Nicotine Delivery Systems and Airway Epithelial Biology

NCT01974063
Conditions
Smoking, Smoking Cessation
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
New York, New York
Conditions
Chronic Obstructive Pulmonary Disease, HIV, Emphysema
Interventions
blood draw, questionnaires, Lung function testing, Six-Minute walk test, Quantitative CT scans, Nasal secretion and cell collection, Echocardiogram
Procedure · Radiation
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cerebral Ischemia
Interventions
SANGUINATE™
Biological
Lead sponsor
Prolong Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Carbon Monoxide Exposure
Interventions
Not listed
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Acute Respiratory Distress Syndrome, Sepsis
Interventions
Inhaled Carbon Monoxide at CFK equation-determined personalized dose (200-500 ppm to achieve a COHb level of 6-8%), Inhaled Medical air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 2 more
Completed No phase listed Observational Accepts healthy volunteers

Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin

NCT01583634
Conditions
Healthy Volunteers
Interventions
Mespere Oximeter, Radiometer OSM-3 Co-Oximeter
Device
Lead sponsor
Mespere Lifesciences Inc.
Industry
Eligibility
21 Years to 49 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
San Francisco, California