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ClinicalTrials.gov public records Last synced Sep 25, 2026, 4:57 PM EDT

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Showing 1–24 of 175 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cardiac Ablation for Atrial Fibrillation Clear all
Recruiting Not applicable Interventional

A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation

NCT07523750
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
VARIPULSE Catheter, FARAWAVE Catheter
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
10
States / cities
Jonesboro, Arkansas • Fountain Valley, California • Ventura, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

ARIADNE Clinical Trial

NCT06747091
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Catheter Ablation
Procedure
Lead sponsor
Stavros E Mountantonakis
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Manhasset, New York • New Hyde Park, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 25, 2026, 4:57 PM EDT
Not listed Phase 2 Interventional

Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI

NCT01959997
View directory record Official record
Conditions
Atrial Fibrillation, Arterial Hypertension
Interventions
Redo PVI, PVI + RDN
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

NCT07298473
View directory record Official record
Conditions
Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)
Interventions
Sphere-9 Catheter Ablation
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
22
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Phase 2 Interventional Results available

Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery

NCT00903370
View directory record Official record
Conditions
Atrial Fibrillation, Mitral Valve Insufficiency, Mitral Valve Stenosis
Interventions
MVS, Ablation
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
18
States / cities
New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Terminated Not applicable Interventional Results available

Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation

NCT01122173
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Ablation
Device
Lead sponsor
Hansen Medical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Mesa, Arizona • Rochester, Minnesota • Englewood, New Jersey + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional

One More Magnetic Resonance Imaging

NCT02293070
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Delayed Enhanced Cardiac Magnetic Resonance Imaging, Cryoablation
Other · Procedure
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Terminated Not applicable Interventional Results available

CONcomitant eValuation of Epicor Left atRial Therapy for AF

NCT00519194
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Epicor LP Cardiac Ablation System, Surgical ablation of permanent AF
Device · Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
15
States / cities
Fresno, California • Bradenton, Florida • Pensacola, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Phase 3 Interventional Results available

Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) Study

NCT00431834
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardioblate System Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Sep 25, 2026, 4:57 PM EDT
Completed No phase listed Observational Results available

Early Detection and Treatment of Esophageal Injury After Catheter Ablation for Atrial Fibrillation

NCT00584922
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Endoscopy in group I (all patients)
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)

NCT01661205
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Ablation procedure staged catheter ablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
4
States / cities
Stanford, California • Colorado Springs, Colorado • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Amigo Robotic System for Ablation of the Cavo-Tricuspid Isthmus

NCT02467179
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Amigo™ Robotic Catheter Manipulation, Manual Catheter Manipulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness of TactiCath™ Contact Force, Sensor Enabled™ (TactiCath SE) Catheter for Ablation of Drug Refractory, Symptomatic, Persistent Atrial Fibrillation

NCT03650556
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
TactiCath™ Contact Force Ablation Catheter, Sensor Enabled™
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
20
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 25, 2026, 4:57 PM EDT
Completed No phase listed Observational Results available

Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation

NCT03729830
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Boston Scientific Open Irrigated Ablation Catheters
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
20 Years and older
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
18
States / cities
Birmingham, Alabama • Torrance, California • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Active, not recruiting Not applicable Interventional

Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

NCT06735534
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
FARAPULSE™ Pulsed Field Ablation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
33
States / cities
Mobile, Alabama • Jonesboro, Arkansas • Los Angeles, California + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Renal Denervation + PVI vs PVI Alone for Persistent AF

NCT05116384
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
catheter ablation, renal artery denervation
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Short Hills, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 25, 2026, 4:57 PM EDT
Active, not recruiting Not applicable Interventional

Pulsed-Field Ablation With/Without Electrogram Mapping

NCT07541989
View directory record Official record
Conditions
Non-paroxysmal Atrial Fibrillation
Interventions
PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone
Procedure
Lead sponsor
Xu Liu
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Withdrawn Phase 4 Interventional

Catheter Ablation for Recently Diagnosed Paroxysmal Atrial Fibrillation

NCT01505296
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Antiarrhythmic drug, Catheter ablation
Drug · Procedure
Lead sponsor
Valley Health System
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation

NCT01278953
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Catheter ablation to treat paroxysmal atrial fibrillation
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Sep 25, 2026, 4:57 PM EDT
Completed No phase listed Observational

Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients

NCT07580937
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Arrhythmia
Interventions
Data collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
10
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional Results available

Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation

NCT04133168
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Boston Scientific Cardiac Cryoablation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
30
States / cities
Phoenix, Arizona • Tucson, Arizona • Jonesboro, Arkansas + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Not applicable Interventional

LS-PersAFone: Pulsed Field Ablation for Long-Standing Persistent Atrial Fibrillation

NCT06128174
View directory record Official record
Conditions
Long-standing Persistent AF
Interventions
Farawave PFA catheter
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 25, 2026, 4:57 PM EDT
Completed Phase 3 Interventional Results available

Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/Persistent

NCT00506493
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardioblate Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiac Surgery
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 25, 2026, 4:57 PM EDT