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Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cardiac Resynchronization Therapy Defibrillator Clear all
Completed No phase listed Observational

Conduction System Pacing International Registry (CONSPIRE)

NCT04831125
View directory record Official record
Conditions
Bradyarrhythmia, Heart Failure
Interventions
Data collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
Tucson, Arizona • Chicago, Illinois • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Automatic Testing Feature in New ICDs and CRT-Ds

NCT00746356
View directory record Official record
Conditions
Heart Failure, Ventricular Arrythmias
Interventions
Testing of the autocapture features of the device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
5
States / cities
Little Rock, Arkansas • Browns Mills, New Jersey • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Terminated Phase 3 Interventional Results available

AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study

NCT00589303
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure
Interventions
FDA approved rate and rhythm control drugs, AV Node ablation and device implant
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Scottsdale, Arizona • Evansville, Indiana • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

Promote Q Cardiac Resynchronization Therapy Defibrillator (CRT-D) and Quartet Left Ventricular Heart Lead Study

NCT00990665
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D and LV lead (Quartet™ lead and Promote Q® device system)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Glendale, California + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Phase 4 Interventional Results available

OptiVol® Care Pathway

NCT00847288
View directory record Official record
Conditions
Heart Failure
Interventions
Monthly Review Arm, Quarterly Review Arm
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
108
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 105 more
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Sep 3, 2026, 6:55 PM EDT
Terminated No phase listed Observational Results available

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

NCT05704426
View directory record Official record
Conditions
Atrial Fibrillation, Arrythmia
Interventions
Impulse Dynamics Optimizer Device
Device
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational

HBP Device EGM Data Collection

NCT03564860
View directory record Official record
Conditions
Sick Sinus Syndrome, AV Block, Heart Failure
Interventions
Device data collection
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Sep 3, 2026, 6:55 PM EDT
Withdrawn Phase 4 Interventional

Remote Interrogation in Rural Emergency Departments

NCT02421549
View directory record Official record
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational

RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-D

NCT00453622
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy-Defibrillator
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 90 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational

LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices

NCT02091011
View directory record Official record
Conditions
Implantable Cardioverter Defibrillators, CRT-D Cardiac Resynchronization Therapy Defibrillator
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
51
States / cities
Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 3, 2026, 6:55 PM EDT
Active, not recruiting No phase listed Observational

Factors Associated With Response to Cardiac Resynchronization Therapy in Heart Failure Patients With Non-LBBB ECG Pattern

NCT06977217
View directory record Official record
Conditions
Cardiomyopathies, Heart Failure, Non-left Bundle Branch Block, Cardiac Resynchronization Therapy
Interventions
CRT-D implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Phase 4 Interventional Results available

'Effect of CRT on Defibrillation Threshold Estimates' Study

NCT00626093
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Cardiac Resynchronization Therapy - Defibrillator (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Santa Monica, California • Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

Evaluation of ACUITY™ X4 Quadripolar Coronary Venous Leads and RELIANCE™ 4-FRONT Defibrillation Leads

NCT02071173
View directory record Official record
Conditions
Cardiac Resynchronization Therapy
Interventions
ACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
96
States / cities
Birmingham, Alabama • Huntsville, Alabama • Anchorage, Alaska + 85 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Sep 3, 2026, 6:55 PM EDT
Recruiting Not applicable Interventional

Left vs Left Randomized Clinical Trial

NCT05650658
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB, RBBB, Intraventricular Conduction Delay, Pacing-Induced Cardiomyopathy
Interventions
His/LBBP, BiVP
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
2,136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
57
States / cities
Gilbert, Arizona • Tucson, Arizona • Little Rock, Arkansas + 46 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational

Reverse Electrical Remodeling of Native Conduction in Cardiac Resynchronization Therapy

NCT01924221
View directory record Official record
Conditions
Heart Failure, Patients Undergoing CRT-D Device Implantation
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 29, 2022 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Strategic Management to Optimize Response To Cardiac Resynchronization Therapy

NCT03089281
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
699 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
41
States / cities
Birmingham, Alabama • Huntsville, Alabama • Tucson, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Sep 3, 2026, 6:55 PM EDT
Completed No phase listed Observational Results available

PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure

NCT00279955
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Cardiac Resynchronization Therapy Device
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
93
States / cities
Huntsville, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 90 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Phase 4 Interventional Results available

POWER (Pulse Width Optimized Waveform Evaluation Trial)

NCT00311181
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronization Therapy (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Birmingham, Alabama • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Sep 3, 2026, 6:55 PM EDT
Terminated Phase 4 Interventional Results available

Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk

NCT00559988
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Stroke, Embolism, Systemic Arterial, Major Bleeding
Interventions
Home Monitoring Guided OAC, Physician-Directed OAC
Drug
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
73
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Anaheim, California + 70 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2017 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Phase 3 Interventional

CONTAK RENEWAL 3 AVT

NCT00158977
View directory record Official record
Conditions
Heart Failure, Atrial Fibrillation
Interventions
CONTAK RENEWAL 3 AVT
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2011 · Synced Sep 3, 2026, 6:55 PM EDT
Terminated No phase listed Observational Results available

Optisure Lead Post Approval Study

NCT02235545
View directory record Official record
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
St. Jude Medical Optisure Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,735 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
46
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 42 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF)

NCT00267098
View directory record Official record
Conditions
Atrioventricular Block, Heart Diseases
Interventions
Cardiac Resynchronization Therapy (CRT)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
918 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
51
States / cities
Anchorage, Alaska • Peoria, Arizona • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 3, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

NCT00271154
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
34
States / cities
Huntsville, Alabama • Anchorage, Alaska • Redwood City, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2012 · Synced Sep 3, 2026, 6:55 PM EDT