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ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:17 AM EDT

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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cardiac Resynchronization Therapy Device Clear all
Terminated Not applicable Interventional Results available

Right Ventricular Septal Pacing in Patients With Right Bundle Branch Block and Heart Failure (The SPARK Trial)

NCT02441101
View directory record Official record
Conditions
Right Bundle-Branch Block, Heart Failure
Interventions
RV DDD(R)-60 with AV optimization, RV DDD(R)-60
Device
Lead sponsor
Barry London
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy

NCT04561778
View directory record Official record
Conditions
Heart Failure，Congestive, Cardiomyopathies, Left Ventricular Dysfunction
Interventions
HOT-CRT, Biventricular Pacing
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 26, 2026, 2:17 AM EDT
Completed No phase listed Observational

HBP Device EGM Data Collection

NCT03564860
View directory record Official record
Conditions
Sick Sinus Syndrome, AV Block, Heart Failure
Interventions
Device data collection
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated Early Phase 1 Interventional

A Pilot Study Comparing the Programmed Delay Between the Atrial and Ventricle Interval

NCT00794183
View directory record Official record
Conditions
Heart Failure
Interventions
CRT device settings
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 26, 2012 · Synced Oct 26, 2026, 2:17 AM EDT
Completed No phase listed Observational

RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-D

NCT00453622
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy-Defibrillator
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 90 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated Not applicable Interventional Results available

Biventricular Versus Right Ventricular Pacing

NCT06298669
View directory record Official record
Conditions
Heart Failure
Interventions
Biventricular Pacing, Right Ventricular Pacing
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated No phase listed Observational Results available

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

NCT05704426
View directory record Official record
Conditions
Atrial Fibrillation, Arrythmia
Interventions
Impulse Dynamics Optimizer Device
Device
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 26, 2026, 2:17 AM EDT
Completed No phase listed Observational

LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices

NCT02091011
View directory record Official record
Conditions
Implantable Cardioverter Defibrillators, CRT-D Cardiac Resynchronization Therapy Defibrillator
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
51
States / cities
Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

ECG Belt to Assess Electrical Synchronization

NCT04583709
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
ECG Belt
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 26, 2026, 2:17 AM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

NCT07069738
View directory record Official record
Conditions
Heart Failure - NYHA II - IV
Interventions
CRT-D with a Quadripolar LV lead, CRT-D with INGEVITY+ pace/sense lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
42
States / cities
Huntsville, Alabama • Mobile, Alabama • Phoenix, Arizona + 36 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Phase 4 Interventional Results available

OptiVol® Care Pathway

NCT00847288
View directory record Official record
Conditions
Heart Failure
Interventions
Monthly Review Arm, Quarterly Review Arm
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
108
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 105 more
Source: ClinicalTrials.gov public record
Updated May 3, 2013 · Synced Oct 26, 2026, 2:17 AM EDT
Withdrawn Not applicable Interventional

Patent Foramen Ovale (PFO) Closure at the Time of Endovascular Cardiac Electronic Device Implantation

NCT03232450
View directory record Official record
Conditions
Foramen Ovale, Patent
Interventions
Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 26, 2026, 2:17 AM EDT
Completed No phase listed Observational

Cardiac Resynchronization Therapy (CRT) and Left Ventricular Assist Devices (LVAD) Therapy

NCT02083419
View directory record Official record
Conditions
Heart Failure
Interventions
LVAD CRT
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging

NCT01129635
View directory record Official record
Conditions
Heart Failure, Systolic, Left Bundle Branch Block
Interventions
Cardiac Resynchronization Therapy (CRT) implantation
Procedure
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 21, 2015 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Optimization of CRT Using an ECG Vest

NCT02699944
View directory record Official record
Conditions
Heart Failure
Interventions
ECG Vest Optimization
Device
Lead sponsor
Alan J. Bank, MD
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy

NCT02700425
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
CRT Pacemaker
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
8
States / cities
Los Angeles, California • Chicago, Illinois • Naperville, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Engaging Patients in Heart Failure Management

NCT02682251
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
PHR Messaging
Other
Lead sponsor
Parkview Health
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 26, 2026, 2:17 AM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Promote Q Cardiac Resynchronization Therapy Defibrillator (CRT-D) and Quartet Left Ventricular Heart Lead Study

NCT00990665
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D and LV lead (Quartet™ lead and Promote Q® device system)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Glendale, California + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated Not applicable Interventional

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

NCT02783716
View directory record Official record
Conditions
Heart Failure
Interventions
Subcutaneous adipose tissue collection, Peripheral arterial tonometry (PAT)
Procedure · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 26, 2026, 2:17 AM EDT
Terminated Not applicable Interventional Results available

Integrated Diagnostics Driven Diuretic and Chronic Medication Management for Heart Failure

NCT02698241
View directory record Official record
Conditions
Heart Failure
Interventions
Diagnostic & Medication Management
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
8
States / cities
Phoenix, Arizona • Ft. Pierce, Florida • Jacksonville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2019 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional Results available

Junctional AV Ablation in CRT-D: JAVA-CRT

NCT02946853
View directory record Official record
Conditions
Systolic Heart Failure, Atrial Fibrillation (Permanent)
Interventions
Atrioventricular junctional (AVJ) ablation, Cardiac resynchronization therapy - defibrillator
Procedure · Device
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
21
States / cities
Little Rock, Arkansas • Pasadena, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 26, 2026, 2:17 AM EDT
Completed Not applicable Interventional

Comparison of Epicardial Versus Conventional Lead Placement in Cardiac Resynchronization Therapy

NCT01302470
View directory record Official record
Conditions
Cardiac Resynchronization Therapy, Heart Failure
Interventions
Primary epicardial placement of left ventricular lead, Transvenous placement of left ventricular lead
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2015 · Synced Oct 26, 2026, 2:17 AM EDT