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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:00 AM EST

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Cardiac Resynchronization Therapy Pacemaker Clear all

Conditions: Heart Failure
Interventions: Cardiac resynchronization therapy pacemaker (CRT-P); Device
Lead sponsor: Yong-Mei Cha; Other
Eligibility: 18 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bradycardia, Heart Failure
Interventions: CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation; Procedure
Lead sponsor: Yong-Mei Cha; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure
Interventions: Subcutaneous adipose tissue collection, Peripheral arterial tonometry (PAT); Procedure · Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy; Device
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Bradyarrhythmia, Heart Failure
Interventions: Data collection; Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 383 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 5
States / cities: Tucson, Arizona • Chicago, Illinois • New York, New York + 2 more

Conditions: Ischemic Mitral Regurgitation
Interventions: Ranolazine (Active drug), Placebo; Drug
Lead sponsor: University Cardiology; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Heart Failure, Congestive
Interventions: Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement; Procedure
Lead sponsor: Stereotaxis; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 3
States / cities: Gainesville, Georgia • Charleston, South Carolina • Richmond, Virginia

Conditions: Heart Failure
Interventions: Medtronic Pacemaker; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Cardiovascular Disease
Interventions: Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Heart Failure, Systolic
Interventions: Optimization of CRT Device; Diagnostic Test
Lead sponsor: Alan J. Bank, MD; Other
Eligibility: 18 Years to 110 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Heart Failure, Cardiomyopathy
Interventions: Cardiac resynchronization therapy device; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 51
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 48 more

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy Device; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 430 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 32
States / cities: Birmingham, Alabama • Newport Beach, California • Trumbull, Connecticut + 29 more

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy Pacemaker, Cardiac Resynchronization Therapy Defibrillator; Device
Lead sponsor: Samir Saba; Other
Eligibility: 75 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 6
States / cities: Durham, North Carolina • Columbus, Ohio • Erie, Pennsylvania + 2 more

Conditions: Heart Failure
Interventions: Not listed
Lead sponsor: Respicardia, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 6
States / cities: Birmingham, Alabama • Baltimore, Maryland • Cincinnati, Ohio + 3 more

Conditions: Cardiomyopathies, Heart Failure, Non-left Bundle Branch Block, Cardiac Resynchronization Therapy
Interventions: CRT-D implantation; Procedure
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Heart Failure，Congestive, Cardiomyopathies, Left Ventricular Dysfunction
Interventions: HOT-CRT, Biventricular Pacing; Device
Lead sponsor: Pugazhendhi Vijayaraman; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Danville, Pennsylvania

Conditions: Congestive Heart Failure
Interventions: Cardiac Resynchronization Therapy with & without defibrillator; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 2,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2002
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Atrial Fibrillation, Arrythmia
Interventions: Impulse Dynamics Optimizer Device; Device
Lead sponsor: Hackensack Meridian Health; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Hackensack, New Jersey

Conditions: Foramen Ovale, Patent
Interventions: Aspirin, Cardiovascular Implantable Device (CIED), Gore Cardioform Septal Occluder; Drug · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: LVAD (Left Ventricular Assist Device) Driveline Infection
Interventions: Temporary changes in an already-implanted medical device (biventricular pacemaker); Other
Lead sponsor: University of California, Davis; Other
Eligibility: Not listed
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Heart Failure, Congestive
Interventions: Cardiac Resynchronization Therapy Device; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 1,024 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 93
States / cities: Huntsville, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 90 more

Conditions: Sick Sinus Syndrome, AV Block, Heart Failure
Interventions: Device data collection; Procedure
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 3
States / cities: Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina

Conditions: Congestive Heart Failure
Interventions: Not listed
Lead sponsor: Saint Luke's Health System; Other
Eligibility: 18 Years to 90 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 2
States / cities: Elgin, Illinois • Oklahoma City, Oklahoma

Conditions: Congestive Heart Failure
Interventions: CRT Pacemaker; Device
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 8
States / cities: Los Angeles, California • Chicago, Illinois • Naperville, Illinois + 3 more

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Metabolic Mapping and Cardiac Resynchronization

His Bundle Pacing in Bradycardia and Heart Failure

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

Impact of Cardiac Resynchronization Therapy on Right Ventricular Function in Left Ventricular Assist Device Patients

Conduction System Pacing International Registry (CONSPIRE)

Effect of Ranolazine on Valvular Disease in Patients With Pacemakers

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

ECG Belt vs. Echocardiographic Optimization of CRT

InSync Implantable Cardioverter Defibrillator Registry: Cardiac Resynchronization Therapy

Ensure Cardiac Resynchronization Therapy Study

Cardiac Resynchronization in the Elderly

Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

Factors Associated With Response to Cardiac Resynchronization Therapy in Heart Failure Patients With Non-LBBB ECG Pattern

HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy

Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

Patent Foramen Ovale (PFO) Closure at the Time of Endovascular Cardiac Electronic Device Implantation

Effect of Cardiac Resynchronization Therapy (CRT) on Left Ventricular Assist Device (LVAD) Function

PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure

HBP Device EGM Data Collection

The Registry Evaluating Functional Outcomes of Resynchronization Management

His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy