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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cardiac Resynchronization Therapy-Defibrillator Clear all
Terminated Not applicable Interventional Results available

Substrate Targeted Ablation Using the FlexAbility™ Ablation Catheter System for the Reduction of Ventricular Tachycardia

NCT02130765
View directory record Official record
Conditions
Monomorphic Ventricular Tachycardia
Interventions
Cardiac catheter ablation with ICD/CRT-D
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
30
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 20, 2026, 7:19 PM EDT
Completed No phase listed Observational

Conduction System Pacing International Registry (CONSPIRE)

NCT04831125
View directory record Official record
Conditions
Bradyarrhythmia, Heart Failure
Interventions
Data collection
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
Tucson, Arizona • Chicago, Illinois • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 20, 2026, 7:19 PM EDT
Terminated No phase listed Observational Results available

OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.

NCT00277524
View directory record Official record
Conditions
Tachycardia, Ventricular, Heart Failure, Congestive, Ventricular Fibrillation, Ventricular Dysfunction, Bradycardia
Interventions
Not listed
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
3,032 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
113
States / cities
Tucson, Arizona • Little Rock, Arkansas • Fresno, California + 107 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2013 · Synced Sep 20, 2026, 7:19 PM EDT
Terminated No phase listed Observational Results available

Optisure Lead Post Approval Study

NCT02235545
View directory record Official record
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
St. Jude Medical Optisure Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,735 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
46
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 42 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Not applicable Interventional Results available

Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF)

NCT00267098
View directory record Official record
Conditions
Atrioventricular Block, Heart Diseases
Interventions
Cardiac Resynchronization Therapy (CRT)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
918 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
51
States / cities
Anchorage, Alaska • Peoria, Arizona • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 20, 2026, 7:19 PM EDT
Not listed No phase listed Observational

The Registry Evaluating Functional Outcomes of Resynchronization Management

NCT00959179
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Elgin, Illinois • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 13, 2009 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Phase 2Phase 3 Interventional

Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure

NCT00180258
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Cardiac Resynchronization Therapy with & without defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 24, 2007 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Not applicable Interventional Results available

Cardiac Resynchronization in the Elderly

NCT03031847
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy Pacemaker, Cardiac Resynchronization Therapy Defibrillator
Device
Lead sponsor
Samir Saba
Other
Eligibility
75 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Durham, North Carolina • Columbus, Ohio • Erie, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 20, 2026, 7:19 PM EDT
Enrolling by invitation No phase listed Observational

Lead Evaluation for Defibrillation and Reliability Post Approval Study

NCT07005232
View directory record Official record
Conditions
Tachyarrhythmia
Interventions
defibrillation lead
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
52
States / cities
Birmingham, Alabama • Stanford, California • Torrance, California + 45 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Phase 4 Interventional Results available

POWER (Pulse Width Optimized Waveform Evaluation Trial)

NCT00311181
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronization Therapy (CRT-D)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Birmingham, Alabama • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Not applicable Interventional Results available

Evaluation of ACUITY™ X4 Quadripolar Coronary Venous Leads and RELIANCE™ 4-FRONT Defibrillation Leads

NCT02071173
View directory record Official record
Conditions
Cardiac Resynchronization Therapy
Interventions
ACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
96
States / cities
Birmingham, Alabama • Huntsville, Alabama • Anchorage, Alaska + 85 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Phase 2 Interventional

Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device

NCT00957541
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Paradym CRT + Physiological Diagnosis (PhD)
Device
Lead sponsor
ELA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Sep 20, 2026, 7:19 PM EDT
Completed No phase listed Observational

RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-D

NCT00453622
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy-Defibrillator
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 90 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 20, 2026, 7:19 PM EDT
Not yet recruiting Not applicable Interventional

Cardiac Anodal Biphasic Pacing

NCT07173777
View directory record Official record
Conditions
Cardiac Pacing
Interventions
Cardiac Waveform Generator
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 20, 2026, 7:19 PM EDT
Completed No phase listed Observational Results available

Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy Post Approval Registry

NCT01294449
View directory record Official record
Conditions
Heart Failure
Interventions
MADIT-CRT ICD, MADIT-CRT CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Not applicable Interventional Results available

Remote Device Interrogation In The Emergency Department

NCT01871090
View directory record Official record
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Zanesville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Phase 2 Interventional Results available

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

NCT02104583
View directory record Official record
Conditions
Ventricular Arrhythmia
Interventions
Eleclazine, Placebo to match eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
37
States / cities
Mesa, Arizona • Long Beach, California • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Sep 20, 2026, 7:19 PM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Sep 20, 2026, 7:19 PM EDT
Completed Not applicable Interventional Results available

Junctional AV Ablation in CRT-D: JAVA-CRT

NCT02946853
View directory record Official record
Conditions
Systolic Heart Failure, Atrial Fibrillation (Permanent)
Interventions
Atrioventricular junctional (AVJ) ablation, Cardiac resynchronization therapy - defibrillator
Procedure · Device
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
21
States / cities
Little Rock, Arkansas • Pasadena, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Sep 20, 2026, 7:19 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)

NCT00683696
View directory record Official record
Conditions
Heart Failure, Ventricular Dyssynchrony
Interventions
Implantable Cardioverter Defibrillator with Cardiac Resynchronization Therapy (BIOTRONIK Lumax HF-T CRT-D)
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
62
States / cities
Concord, California • Los Angeles, California • Rancho Mirage, California + 46 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Sep 20, 2026, 7:19 PM EDT
Recruiting No phase listed Observational

His Bundle Pacing in Bradycardia and Heart Failure

NCT03008291
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation
Procedure
Lead sponsor
Yong-Mei Cha
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 20, 2026, 7:19 PM EDT
Completed No phase listed Observational

Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation

NCT02134379
View directory record Official record
Conditions
Heart Failure; With Decompensation
Interventions
Medtronic ICDs, CRT-Ds, and CRT-Ps
Device
Lead sponsor
Charles Porter, MD
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 20, 2026, 7:19 PM EDT
Terminated No phase listed Observational

Correlation Of Respiratory Rate Level And Trend Evaluation in Heart Failure Patients

NCT00758121
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy Defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2009 · Synced Sep 20, 2026, 7:19 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial

NCT00382863
View directory record Official record
Conditions
Heart Failure
Interventions
HeartNet Ventricular Support System, Optimal Medical/Device Therapy
Device · Drug
Lead sponsor
Paracor Medical, Inc
Industry
Eligibility
18 Years to 74 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
29
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2012 · Synced Sep 20, 2026, 7:19 PM EDT