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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:07 AM EDT

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Showing 1–24 of 172 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cardiac resynchronization therapy Clear all
Completed Not applicable Interventional Results available

ECG Belt to Assess Electrical Synchronization

NCT04583709
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
ECG Belt
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 29, 2026, 4:07 AM EDT
Not listed Phase 4 Interventional

Effect of Ranolazine on Valvular Disease in Patients With Pacemakers

NCT01979965
View directory record Official record
Conditions
Ischemic Mitral Regurgitation
Interventions
Ranolazine (Active drug), Placebo
Drug
Lead sponsor
University Cardiology
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 8, 2013 · Synced Oct 29, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Results available

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

NCT00698139
View directory record Official record
Conditions
Heart Failure
Interventions
Medtronic Pacemaker
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Phase 4 Interventional Results available

Comparison of AV Optimization Methods Used in Cardiac Resynchronization Therapy (CRT)

NCT00677014
View directory record Official record
Conditions
Heart Failure
Interventions
AV Delay programming through cardiac resynchronization therapy
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,060 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 29, 2026, 4:07 AM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 29, 2026, 4:07 AM EDT
Withdrawn No phase listed Observational

Pilot Study Using Echocardiography to Evaluate Patients With Heart Failure and Dyssynchrony Who Have a CRT-D Device

NCT01127334
View directory record Official record
Conditions
Systolic Heart Failure
Interventions
Not listed
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 4, 2012 · Synced Oct 29, 2026, 4:07 AM EDT
Terminated Not applicable Interventional

Optimizing CRT With ECGI

NCT03492788
View directory record Official record
Conditions
Heart Failure, Systolic, Left Bundle-Branch Block
Interventions
ECGI-optimized VV-offset, Zero VV-offset
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional

Left Ventricular Capture Management (LVCM) Software Download Clinical Trial

NCT00268281
View directory record Official record
Conditions
Heart Failure
Interventions
Left Ventricular Capture Management Software
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
18
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Palo Alto, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2006 · Synced Oct 29, 2026, 4:07 AM EDT
Not listed Not applicable Interventional

Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients

NCT04083690
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Reprogramming of CRT Device Settings to Optimal Electrical Synchrony
Device
Lead sponsor
Allina Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Phase 4 Interventional Results available

Response of Cardiac Resynchronization Therapy Optimization With Ventricle to Ventricle Timing in Heart Failure Patients

NCT00187200
View directory record Official record
Conditions
Heart Failure
Interventions
Simultaneous VV Pacing, Sequential VV Pacing
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 29, 2026, 4:07 AM EDT
Enrolling by invitation No phase listed Observational

Lead Evaluation for Defibrillation and Reliability Post Approval Study

NCT07005232
View directory record Official record
Conditions
Tachyarrhythmia
Interventions
defibrillation lead
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
52
States / cities
Birmingham, Alabama • Stanford, California • Torrance, California + 45 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional Results available

Sensor Optimization of Cardiac Resynchronization Therapy Response

NCT01832493
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Des Moines, Iowa • Columbus, Ohio • Fairfield, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional Results available

Adaptive CRT Effect on Electrical Dyssynchrony

NCT02543281
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure, Left Bundle Branch Block
Interventions
Adaptive cardiac resynchronization therapy, Conventional Cardiac Resynchronization Therapy
Device
Lead sponsor
Larisa Tereshchenko
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 29, 2026, 4:07 AM EDT
Completed No phase listed Observational

3T MRI CIED Post-Approval Study

NCT02969395
View directory record Official record
Conditions
Cardiac Rhythm Disorder
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
118
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 115 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 29, 2026, 4:07 AM EDT
Recruiting Not applicable Interventional

His-Bundle Corrective Pacing in Heart Failure

NCT05265520
View directory record Official record
Conditions
Right Bundle-Branch Block, Heart Failure, His-bundle Pacing, Cardiac Resynchronization Therapy
Interventions
His-CRT implantation, BIV-CRT implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
14
States / cities
Phoenix, Arizona • Los Angeles, California • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional

Clinical Investigation of the Medtronic Concerto™ Device

NCT00268320
View directory record Official record
Conditions
Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation
Interventions
Cardiac Resynchronization Therapy+Implantable Cardioverter Defibrillator
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
30
States / cities
Anchorage, Alaska • Phoenix, Arizona • Santa Monica, California + 27 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2008 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional

Cardiac Resynchronization Therapy Defibrillator Based Impedance Monitoring Study

NCT00500838
View directory record Official record
Conditions
Heart Failure
Interventions
Transthoracic Impedance
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
4
States / cities
Little Rock, Arkansas • Glendale, California • Browns Mills, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2019 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial - Chemotherapy-Induced Cardiomyopathy

NCT02164721
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Three-lead CRT-D (Defibrillator)
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 29, 2026, 4:07 AM EDT
Completed No phase listed Observational

Prospective Minnesota Study of ECHO Tissue Doppler Imaging in Cardiac Resynchronization Therapy

NCT00158015
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
7
States / cities
Coon Rapids, Minnesota • Edina, Minnesota • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Not applicable Interventional

Atrio-Ventricular (AV) Delay Optimization Using Echocardiography Versus the SonR Signal

NCT01287234
View directory record Official record
Conditions
Heart Failure
Interventions
Echocardiogram/SonR
Other
Lead sponsor
Piedmont Healthcare
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Phase 4 Interventional Results available

PEGASUS CRT Study: Atrial Support Study in Cardiac Resynchronization Therapy

NCT00146848
View directory record Official record
Conditions
Heart Failure
Interventions
Atrial support pacing through cardiac resynchronization therapy. Device: RENEWAL family of CRT-D devices
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,742 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2011 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Phase 4 Interventional Results available

OptiVol® Care Pathway

NCT00847288
View directory record Official record
Conditions
Heart Failure
Interventions
Monthly Review Arm, Quarterly Review Arm
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
108
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 105 more
Source: ClinicalTrials.gov public record
Updated May 3, 2013 · Synced Oct 29, 2026, 4:07 AM EDT
Terminated Phase 4 Interventional

MAGNET CRT Feasibility - Efficiency of LV Lead Placement Comparing Conventional vs. Magnetic Guidance

NCT00370474
View directory record Official record
Conditions
Cardiac Resynchronization Therapy
Interventions
Bi-ventricular lead placement
Device
Lead sponsor
Stereotaxis
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
6
States / cities
Gainesville, Georgia • Lexington, Kentucky • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2007 · Synced Oct 29, 2026, 4:07 AM EDT
Completed Phase 2 Interventional Results available

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

NCT02104583
View directory record Official record
Conditions
Ventricular Arrhythmia
Interventions
Eleclazine, Placebo to match eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
37
States / cities
Mesa, Arizona • Long Beach, California • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 29, 2026, 4:07 AM EDT