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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Care Management for Postpartum Depression Clear all
Recruiting Not applicable Interventional

Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension

NCT05884190
View directory record Official record
Conditions
Postpartum Hypertension
Interventions
Remote Medical Model (RMM), Community Health Model (CHM), SoC
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
6,030 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
New Haven, Connecticut • Worcester, Massachusetts • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 22, 2026, 1:27 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Well-Mama Community Doula Navigator Study

NCT05179369
View directory record Official record
Conditions
Pregnancy Related
Interventions
Standard Care with Well-Mama Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
15 Years to 49 Years · Female only
Enrollment
576 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

MOMCare: Culturally Relevant Treatment Services for Perinatal Depression

NCT01045655
View directory record Official record
Conditions
Depression
Interventions
MOMCare
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Sep 22, 2026, 1:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Curio Digital Therapy for the Treatment of Post-partum Depression

NCT05958095
View directory record Official record
Conditions
PostPartum Depression
Interventions
MamaLift Plus, Digital Sham App
Device
Lead sponsor
Healthcare Innovation Technology Lab
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong, Essentials for Mothers of Newborns) Delivered Using an Electronic App

NCT05518162
View directory record Official record
Conditions
Post-partum Depression
Interventions
InBloom, ROSE
Device · Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital

NCT05225025
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety
Interventions
ROSE, Standard of Care
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2022 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk

NCT06276647
View directory record Official record
Conditions
Maternal Behavior, Postpartum Depression
Interventions
HOME
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression

NCT00602355
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Sertraline, Placebo, Interpersonal psychotherapy (IPT), Clinical management, Mothercrafting
Drug · Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Iowa City, Iowa • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Mental Health in the Hospital Setting

NCT03777046
View directory record Official record
Conditions
Post Partum Depression
Interventions
Standard of Care (SOC), SOC with Psychology Therapy (CBT)
Behavioral
Lead sponsor
Michelle Lopez
Other
Eligibility
18 Years and older · Female only
Enrollment
545 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

T- BOOM Teens--Building Options and Opportunities for Moms

NCT00745537
View directory record Official record
Conditions
Postpartum Major Depression
Interventions
repeated mood measures and phone depression care management
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
10 Years to 17 Years · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Sep 22, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

MOMs Chat and Care Study

NCT06335381
View directory record Official record
Conditions
Severe Maternal Morbidity
Interventions
Maternal Health Education Resources, Prenatal Telehealth Visits, Postpartum Telehealth Visits, Home Blood Pressure Monitor, Fitbit
Other · Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Identification and Therapy of Postpartum Depression

NCT00282776
View directory record Official record
Conditions
Depression
Interventions
Care Management for Postpartum Depression, TAU
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
628 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2013 · Synced Sep 22, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 22, 2026, 1:27 AM EDT
Not listed Not applicable Interventional

Translating Research Into Practice for Postpartum Depression

NCT00548743
View directory record Official record
Conditions
Postpartum Depression
Interventions
Screening and follow up, Usual care
Behavioral
Lead sponsor
Olmsted Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 3, 2007 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Mother-Infant Intervention for Postpartum Depression and Associated Mother-Infant Relationship Dysfunction

NCT02057627
View directory record Official record
Conditions
Postpartum Depression
Interventions
Perinatal Dyadic Psychotherapy, Placebo Comparator
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Family Nurture Intervention in the NICU

NCT02710474
View directory record Official record
Conditions
Premature Birth, Obstetric Labor, Premature
Interventions
Family Nurture Intervention, Standard Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
New York, New York • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers

NCT00436150
View directory record Official record
Conditions
Depression
Interventions
Interpersonal therapy-based treatment, Standard care
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 11, 2013 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

The PATH Home Trial: A Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky

NCT03725332
View directory record Official record
Conditions
Neonatal Abstinence Syndrome
Interventions
Telemedicine, Group Care
Behavioral
Lead sponsor
Wendy F Hansen
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
11
States / cities
Ashland, Kentucky • Bowling Green, Kentucky • Corbin, Kentucky + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse

NCT00602732
View directory record Official record
Conditions
Depression, Postpartum, Depression
Interventions
The Reach Out for a Safe Environment (ROSE) program, Enhanced care as usual (ECU)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 27, 2014 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Navigating New Motherhood 2

NCT03922334
View directory record Official record
Conditions
Postpartum Health, Breastfeeding, Contraception, Preventive Care / Anticipatory Guidance, Retention in Care
Interventions
Patient Navigation Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 22, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

High Pain Intervention in Cesarean Sections

NCT01298778
View directory record Official record
Conditions
Other Chronic Postoperative Pain
Interventions
Duramorph 150, Acetaminophen, Duramorph 300
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 22, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Obstetric Pain Management for Women With Opioid Use Disorder (QUEST)

NCT04308655
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Interview, Surveys
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Sep 22, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Pathways to Perinatal Mental Health Equity

NCT06790641
View directory record Official record
Conditions
Perinatal Anxiety, Perinatal Depression, Social Determinants of Health (SDOH), Peer Support, Obstetric Care, Substance Use Disorder (SUD), Perinatal Depression, Substance Use
Interventions
Program in Support of Moms (PRISM), PSI Peer Support
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 70 Years
Enrollment
1,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Shrewsbury, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 22, 2026, 1:27 AM EDT