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Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Carotenoid Nutritional Supplement Clear all
Completed Phase 2 Interventional Results available

Lycopene in Treating Patients Undergoing Radical Prostatectomy for Prostate Cancer

NCT00450749
View directory record Official record
Conditions
Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage II Prostate Cancer, Stage III Prostate Cancer
Interventions
placebo, therapeutic conventional surgery, laboratory biomarker analysis, lycopene
Other · Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 28, 2026, 2:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

NCT05882084
View directory record Official record
Conditions
Photoaging
Interventions
Astaxanthin 6 mg daily, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

LycoRed 40051 Product as a Countermeasure to Exercise Stress

NCT02369666
View directory record Official record
Conditions
Inflammation
Interventions
LycoRed (code 40051) product, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Phase 1Phase 2 Interventional

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants

NCT01203488
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia, Respiration, Artificial, Respiratory Distress Syndrome, Newborn, Sepsis
Interventions
Vitamin A, Sham Procedure
Drug · Other
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
24 Hours to 96 Hours
Enrollment
807 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 1999
U.S. locations
11
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Sep 28, 2026, 2:44 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Lutein, Zeaxathin, and Fish Oil Supplementation

NCT06489873
View directory record Official record
Conditions
Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
Interventions
Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF), Placebo Comparator
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Nourishing Hair, Skin & Nails Supplement Study (Derm Aid)

NCT04249128
View directory record Official record
Conditions
Hair Loss, Skin Laxity, Cosmetic Acne, Nails; Soft, Skin Aging
Interventions
Vegetarian Collagen, Keratin, Ceramides, Astaxanthin
Dietary Supplement
Lead sponsor
ProofPilot
Industry
Eligibility
26 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lycopene in Preventing Prostate Cancer in Healthy Participants

NCT00093561
View directory record Official record
Conditions
Prostate Cancer
Interventions
lycopene
Dietary Supplement
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 45 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Sep 28, 2026, 2:44 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Macular Pigment and Visual Performance in Glaucoma Patients

NCT03959592
View directory record Official record
Conditions
Glaucoma
Interventions
Lutein, zeaxanthin and mesozeaxanthin, Placebo
Drug · Other
Lead sponsor
Felipe Medeiros, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 2, 2023 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption

NCT05177679
View directory record Official record
Conditions
Cognitive Change, Achievement, Macular Pigmentation
Interventions
Active supplement, Placebo control
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
8 Years to 10 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Vitamin A Absorption From Fortified Bouillon

NCT06438562
View directory record Official record
Conditions
Healthy Volunteers, Vitamin A
Interventions
Unfortified bouillon plus vitamin A in oil, Bouillon fortified with vitamin A #1 plus unfortified oil, Bouillon fortified with vitamin A #2 plus unfortified oil
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Feasibility of Rice Bran Supplementation in Children

NCT02557373
View directory record Official record
Conditions
Dietary Rice Bran Supplementation
Interventions
Vitamin A, Rice Bran + Vitamin A
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
4 Months to 10 Months
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 28, 2026, 2:44 AM EDT
Recruiting Phase 1Phase 2 Interventional

Soy Tomato Juice to Improve Outcomes in Pancreatitis

NCT07447687
View directory record Official record
Conditions
Recurrent Acute Pancreatitis, Chronic Pancreatitis
Interventions
Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 28, 2026, 2:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Lycopene in Preventing Prostate Cancer in Healthy Participants

NCT00322114
View directory record Official record
Conditions
Prostate Cancer
Interventions
lycopene, placebo
Dietary Supplement · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Male only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Feeding the Rainbow to Investigate Endothelial Dysfunction

NCT01175577
View directory record Official record
Conditions
Dietary Modification, Cardiovascular Disease
Interventions
Chlorophyll complex, Standard Process, Betatene, sold as "Full Spectrum Carotenoid Complex", Small carotenoid-rich meals, Placebo
Dietary Supplement · Other
Lead sponsor
Bastyr University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Kenmore, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Sep 28, 2026, 2:44 AM EDT
Not listed Not applicable Interventional

Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG

NCT04117022
View directory record Official record
Conditions
Diabetes, Diabetic Retinopathy
Interventions
DVS supplementation
Dietary Supplement
Lead sponsor
ZeaVision, LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Pomona, California • Tahlequah, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 28, 2026, 2:44 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Eye and Carotenoid Augmentation Research and Evaluation (EyeCARE)

NCT06848101
View directory record Official record
Conditions
Vision, Eye Health
Interventions
Carotenoid Group, Control (placebo) group
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)

NCT03946085
View directory record Official record
Conditions
Retinal Drusen, Age-related Macular Degeneration, Macular Degeneration
Interventions
Lumega-Z, AREDS2
Dietary Supplement
Lead sponsor
Guardion Health Sciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Not applicable Interventional Results available

Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity

NCT02060279
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Lifestyle intervention and carotenoid supplements, Lifestyle intervention and placebo
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 11 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 28, 2026, 2:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a Carotenoid Intervention on Cognitive Function

NCT02023645
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
active supplement, placebo
Dietary Supplement · Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated May 26, 2015 · Synced Sep 28, 2026, 2:44 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60

NCT00121589
View directory record Official record
Conditions
Macular Degeneration
Interventions
Lutein
Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 28, 2026, 2:44 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

A Study to Assess the Impact of a Nutritional Supplement on Wellbeing and Nutrient Absorption

NCT06749808
View directory record Official record
Conditions
Nutrition Status
Interventions
Carotenoid Nutritional Supplement, Placebo
Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
20 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Sep 28, 2026, 2:44 AM EDT
Withdrawn Phase 4 Interventional

Augmented Macular Pigment-containing Nutraceutical and Central Visual Function

NCT04676126
View directory record Official record
Conditions
Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
Interventions
Lumega-Z, Dorzolamide Hcl 2% Oph Soln, Placebo
Dietary Supplement · Drug · Other
Lead sponsor
University of the Incarnate Word
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 28, 2026, 2:44 AM EDT
Terminated Phase 2 Interventional

Lutein and Alzheimer's Disease Study

NCT00596024
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
lutein/zeaxanthin, placebo
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
55 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 28, 2026, 2:44 AM EDT
Not listed Not applicable Interventional

Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-

NCT04843813
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Lutein, Placebo
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 28, 2026, 2:44 AM EDT