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ClinicalTrials.gov public records Last synced Oct 4, 2026, 2:36 AM EDT

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Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Carpal Tunnel Release Clear all
Not listed Phase 2 Interventional

Influence of Pronator Teres Release on Treatment of Median Nerve Compression Neuropathy

NCT01562860
View directory record Official record
Conditions
Median Nerve Compression
Interventions
Pronator Teres Release, dual compression release, median nerve release only
Procedure
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cost Information on Carpal Tunnel Syndrome Treatment Decisions

NCT03880812
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Societal cost
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional

Carpal Tunnel Syndrome: Diagnosis and Treatment Trial

NCT00032227
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

NCT02313675
View directory record Official record
Conditions
Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
Interventions
Acetaminophen, Ketorolac Tromethamine, Saline
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 4, 2026, 2:36 AM EDT
Active, not recruiting Not applicable Interventional

Postoperative Care After Carpal Tunnel Release Using Short Educational Videos

NCT06647719
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Patient Satisfaction
Interventions
Educational Videos
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 4, 2026, 2:36 AM EDT
Completed No phase listed Observational

DUCATS Trial: Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel Syndrome

NCT02219555
View directory record Official record
Conditions
Carpal Tunnel
Interventions
Steroid Injection, Carpel Tunnel surgery
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 80 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional

Ultrasound Guided - Incisionless Threaded Carpal Tunnel Release

NCT04101955
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Incisionless Threaded Carpal Tunnel, Standard Mini-Open Carpal Tunnel
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery

NCT04424810
View directory record Official record
Conditions
Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient, Pain
Interventions
High-quality, physician created video, Standard of care
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional Results available

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

NCT05405218
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS, Carpal Tunnel
Interventions
CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Sonora, California • Fort Walton Beach, Florida • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 4, 2026, 2:36 AM EDT
Recruiting Not applicable Interventional

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

NCT05783245
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Interventions
Polarcare Machine, Standard of care ice therapy
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Minocycline to Reduce Pain After Carpal Tunnel Release

NCT02051296
View directory record Official record
Conditions
Chronic Pain, Post-operative Pain
Interventions
Minocycline, placebo
Drug
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Oct 4, 2026, 2:36 AM EDT
Recruiting Not applicable Interventional

Comparing Efficacy of Osteopathic Manipulation vs. Wrist Immobilization for Carpal Tunnel Syndrome

NCT07432750
View directory record Official record
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
Osteopathic Manipulative Treatment, Wrist Immobilizer
Procedure · Device
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional

Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release

NCT00880295
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
endoscopic carpal tunnel release, open carpal tunnel release
Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 4, 2026, 2:36 AM EDT
Terminated Not applicable Interventional

Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release

NCT05325567
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Mini open incision CTR
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 4, 2026, 2:36 AM EDT
Terminated Not applicable Interventional Results available

PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome

NCT04811287
View directory record Official record
Conditions
Carpal Tunnel Syndrome, PRP
Interventions
Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
Device · Procedure
Lead sponsor
Michael Fredericson, MD
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 4, 2026, 2:36 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Bilateral vs Unilateral CTR

NCT01961011
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2013 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves

NCT00665132
View directory record Official record
Conditions
Unilateral Carpal Tunnel Syndrome
Interventions
StimRouter System
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Oct 4, 2026, 2:36 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Carpal Tunnel Release Using Ultrasound

NCT05031338
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Carpal Tunnel Release, Carpal Tunnel Release
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eagan, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 4, 2026, 2:36 AM EDT
Terminated Not applicable Interventional

Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome

NCT01450735
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
MANOS CTR™
Device
Lead sponsor
Thayer Intellectual Property, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Hayward, California • San Francisco, California • Willits, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 4, 2026, 2:36 AM EDT
Completed No phase listed Observational

Carpal Tunnel Syndrome and Amyloid Cardiomyopathy

NCT02792790
View directory record Official record
Conditions
Amyloidosis, Cardiomyopathy, Transthyretin Amyloidosis, Senile Systemic Amyloidosis, Carpal Tunnel Syndrome
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
50 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2021 · Synced Oct 4, 2026, 2:36 AM EDT
Completed Not applicable Interventional

Early Motion Following Carpal Tunnel Release

NCT00845325
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Group One, Control Group Two
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 29, 2016 · Synced Oct 4, 2026, 2:36 AM EDT