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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 137 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cast Clear all
Active, not recruiting Not applicable Interventional

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

NCT06420245
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Orion TM Amniotic Membrane Allograft, Standard of Care (SOC)
Device · Procedure
Lead sponsor
Legacy Medical Consultants
Industry
Eligibility
50 Years to 85 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
Palm Springs, California • San Francisco, California • Vista, California + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Phase 2 Interventional

Testing the Investigational Agent Combination of Daratumumab, Bortezomib, and Dexamethasone Compared to the Usual Treatment of Cyclophosphamide, Bortezomib, and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients With Kidney Failure

NCT07085728
View directory record Official record
Conditions
Myeloma Multiple
Interventions
Cyclophosphamide, Bortezomib (VELCADE), Dexamethasone, Daratumumab-hyaluronidase
Drug
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2038
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Active, not recruiting Not applicable Interventional

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041
View directory record Official record
Conditions
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Interventions
Casting, Bracing
Procedure · Device
Lead sponsor
University of Iowa
Other
Eligibility
12 Months to 36 Months
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
24
States / cities
Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Distal Radius Buckle Fracture RCT

NCT04032873
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Monetary Cost of Immobilization Treatments, Physician, Study Team, Before Initial Treatment Decision, After Initial Treatment Decision
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
4 Years to 14 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Trial of Social Work Services in Fracture Clinic Setting

NCT06973655
View directory record Official record
Conditions
Orthopaedic Fractures, Socioeconomic Factors
Interventions
Social Work support
Other
Lead sponsor
Sheila Sprague
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Distal Radius Interventions for Fracture Treatment

NCT05131685
View directory record Official record
Conditions
Fracture Distal Radius
Interventions
Reduction, Immobilization
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
4 Years to 10 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
24
States / cities
Phoenix, Arizona • Los Angeles, California • Wilmington, Delaware + 19 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VR to Reduce Pain/Anxiety During Painful Procedures

NCT04268901
View directory record Official record
Conditions
Phlebotomy, Orthopedics, Radiology, Pain, Anxiety, Virtual Reality, Allergy, Gastroenterology
Interventions
Samsung Gear VR, Merge VR, Oculus Go
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
7 Years to 21 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Virtual Reality During Pediatric Cast Removal

NCT03903510
View directory record Official record
Conditions
Fractures, Bone
Interventions
Virtual Reality (VR)
Device
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
4 Years to 12 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 21, 2026, 10:37 PM EDT
Terminated Not applicable Interventional

Cast Sores With Waterproof Vs. Standard Cast Padding

NCT00504855
View directory record Official record
Conditions
Pressure Ulcer
Interventions
Casting using Gortex (waterproof) cast padding materials, Casting using cotton/cotton-poly cast padding materials
Other
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
1 Year to 18 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional

A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures

NCT01589692
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Open Reduction and Internal Fixation, External Fixation, Percutaneous Pinning, Closed Reduction and casting
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
20
States / cities
Farmington, Connecticut • Louisville, Kentucky • Baltimore, Maryland + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns

NCT02681757
View directory record Official record
Conditions
Burns
Interventions
triple antibiotic ointment dressing, Mepitel Ag
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
31 Days to 18 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional

A Longitudinal Study to Evaluate an Extracellular Matrix (MatriStem®) for the Treatment of Diabetic Foot Ulcers

NCT02750280
View directory record Official record
Conditions
Neuropathic Diabetic Foot Ulcer
Interventions
MatriStem® [Urinary Bladder Matrix (UBM)], Mepilex® [Silicone foam dressing]
Device
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers

NCT05417425
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
Combination Product
Lead sponsor
Omeza, LLC
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 21, 2026, 10:37 PM EDT
Completed No phase listed Observational Results available

Comparing Ankle Fusion to Ankle Replacement

NCT01620541
View directory record Official record
Conditions
End-stage Ankle Arthritis (ESAA), Osteoarthritis (OA)
Interventions
Ankle Arthrodesis, Ankle Arthroplasty
Procedure
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
21 Years to 89 Years
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
6
States / cities
Fort Collins, Colorado • Grand Rapids, Michigan • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Comparative Effectiveness of Socket Casting Methods: Improving Form and Fit

NCT04141748
View directory record Official record
Conditions
Lower Limb Amputation
Interventions
Symphonie Aqua SystemTM, Hand Casting
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly

NCT02066857
View directory record Official record
Conditions
Radius; Fracture, Lower or Distal End
Interventions
Cast made of generic plaster or fiberglass cast material, Generic "off the shelf" removable splint
Device
Lead sponsor
Emory University
Other
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Cast or Operation for Medial Epicondyle Fracture Treatment in Children

NCT05131672
View directory record Official record
Conditions
Fracture Elbow
Interventions
open reduction and internal fixation (ORIF), cast immobilization
Procedure
Lead sponsor
Joseph Janicki
Other
Eligibility
7 Years to 17 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Feasibility and Efficacy of Computerized Anxiety Treatment in a Group Setting

NCT06817473
View directory record Official record
Conditions
Computerized Anxiety Sensitivity Treatment, Health Education Treatment
Interventions
CAST, HET
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 21, 2026, 10:37 PM EDT
Withdrawn Not applicable Interventional

Extended vs Flexed Elbow Casting

NCT03935516
View directory record Official record
Conditions
Fracture;Elbow
Interventions
Cast
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 21, 2026, 10:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Muscle Function After Ankle Surgery

NCT00060970
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness, Fractures
Interventions
Physical Therapy
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2000
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 21, 2026, 10:37 PM EDT
Recruiting Not applicable Interventional

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

NCT04828954
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
Other
Lead sponsor
University of Chicago
Other
Eligibility
40 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 10:37 PM EDT
Terminated Not applicable Interventional Results available

Orthopedic Study of the Aircast StabilAir Wrist Fracture Brace

NCT00587795
View directory record Official record
Conditions
Radius Fractures
Interventions
StabilAir Wrist Brace, Placement of sugar tong splint or plaster cast
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Oct 21, 2026, 10:37 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures

NCT02679066
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Sugar-tong splint, Short forearm cast
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 21, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures

NCT05510232
View directory record Official record
Conditions
Fractures, Bone, Deformity; Bone
Interventions
A treatment group that will watch a non-VR video via an iPad, A treatment group that will have headset on and will watch a non-VR video, A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
4 Years to 14 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 21, 2026, 10:37 PM EDT