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ClinicalTrials.gov public records Last synced Oct 18, 2026, 3:51 PM EDT

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Showing 241–264 of 428 matching trials from the live ClinicalTrials.gov search.
Conditions
Cataract
Interventions
Nepafenac ophthalmic solution 0.1%, Ketorolac Tromethamine ophthalmic solution 0.4%, Nepafenac ophthalmic suspension vehicle
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
10 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Cataracts
Interventions
Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL, AcrySof Natural IQ (SN60WF) IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Inflammation, Pain, Cataract
Interventions
XG-102, Placebo
Drug
Lead sponsor
Xigen SA
Industry
Eligibility
18 Years and older
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Andover, Massachusetts
Conditions
Inflammation Eye
Interventions
Dexamethasone
Drug
Lead sponsor
iDrop, Inc.
Industry
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chandler, Arizona
Conditions
Cataract Extraction
Interventions
Moxifloxacin 0.5% ophthalmic solution, Besifloxacin 0.6% ophthalmic suspension
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Interventions
Dextenza 0.4Mg Ophthalmic Insert
Drug
Lead sponsor
Kerry Assil, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Beverly Hills, California
Conditions
Pain, Inflammation
Interventions
Nepafenac PPDS, Placebo PPDS
Combination Product
Lead sponsor
Mati Therapeutics Inc.
Industry
Eligibility
22 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Edgewood, Kentucky • Garden City, New York • Mt. Pleasant, South Carolina
Conditions
Anterior Chamber Inflammation, Ocular Pain, Corneal Edema, Corneal Defect, Penetrating KeratoPlasty, Nuclear Cataract, Cortical Cataract, Cataract Senile
Interventions
Dextenza 0.4Mg Ophthalmic Insert
Drug
Lead sponsor
Nicole Fram M.D.
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Glaucoma
Interventions
KDB/Phacoemulsification, Trabectome/Phacoemulsification
Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 95 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Refractive Errors
Interventions
AccuraSee IOPCL with +3.0D add
Device
Lead sponsor
OnPoint Vision Inc
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bloomington, Minnesota
Conditions
Cataract
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated No phase listed Interventional Accepts healthy volunteers Results available

Whole Eye Optical Coherence Tomography (OCT) to Improve Refractive Surgery and Eye Care

NCT03219567
Conditions
Image, Body
Interventions
Optical Coherence Tomography (OCT), Magnetic resonance imaging (MRI)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Glaucoma, Primary Open Angle, Cataract
Interventions
Intracanalicular Dexamethasone, 0.4 mg insert
Drug
Lead sponsor
Wolstan and Goldberg Eye Associates
Network
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Torrance, California
Completed Not applicable Interventional Results available

Rotational Stability of the AcrySof® Toric

NCT00762216
Conditions
Cataract
Interventions
AcrySof® Toric intraocular lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 80 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Dry Eye
Interventions
Cataract Surgery and Limbal relaxing incision
Procedure
Lead sponsor
Allergan
Industry
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Long Island City, New York
Completed Phase 4 Interventional Accepts healthy volunteers

Pharmacokinetics of Aqueous Dexamethasone

NCT04667507
Conditions
Pharmacokinetics, Aqueous Dexamethasone, Inflammatory Cytokine Response
Interventions
Dexamethasone Ophthalmic implant
Drug
Lead sponsor
Frank A. Bucci, Jr., M.D.
Other
Eligibility
55 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Conditions
Cataract Senile
Interventions
Cataract Surgery
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years to 100 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Beverly Hills, California • Northridge, California • Orange, California + 11 more
Conditions
Cataract
Interventions
SN60AT, SN60WF
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Cataract
Interventions
bromfenac ophthalmic solution, placebo
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Irvine, California
Conditions
Cataract
Interventions
Acrysof Natural ReSTOR SN60D3, Acrysof Natural Monofocal SN60AT
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Cataract
Interventions
Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens

NCT00625313
Conditions
Aphakia
Interventions
HMY Model YA-60BB IOL
Device
Lead sponsor
Hoya Surgical Optics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
617 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chino Hills, California
Conditions
Cataract
Interventions
Simulation based curriculum, Standard training
Other
Lead sponsor
HelpMeSee Inc.
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Cataract Extraction
Interventions
Cataract surgery with Perfect Capsule and Sodium Chloride
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
4 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Charleston, South Carolina