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ClinicalTrials.gov public records Last synced Oct 18, 2026, 5:56 AM EDT

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Showing 73–96 of 428 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cataract Extraction Clear all
Completed Not applicable Interventional Results available

Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).

NCT00758745
View directory record Official record
Conditions
Cataract
Interventions
Model SN60WF, Model MA60AC
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Phacoemulsification at High IOP and Physiologic IOP: Impact on Anterior and Posterior Segment Physiology

NCT05765201
View directory record Official record
Conditions
Nuclear Cataract
Interventions
High IOP, Low IOP
Other
Lead sponsor
Matthew Rauen
Other
Eligibility
Not listed
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
West Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses

NCT04591054
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
Extended Vision IOL, Neutral Aspheric Monofocal IOL
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix

NCT05796453
View directory record Official record
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Relationship Between Advanced Glycation Endproducts and Diabetes

NCT02662010
View directory record Official record
Conditions
Diabetic Retinopathy, Type 2 Diabetes Mellitus
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 80 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery

NCT01296542
View directory record Official record
Conditions
Cataracts
Interventions
Moxifloxacin Ophthalmic, Besifloxacin Ophthalmic
Drug
Lead sponsor
Bucci Laser Vision Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational

Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9

NCT01601665
View directory record Official record
Conditions
Cataracts, Astigmatism
Interventions
SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens, SN6AT9 Intraocular Lens, SN60WF Intraocular Lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation

NCT02235272
View directory record Official record
Conditions
Inflammation, Pain, Cataract
Interventions
XG-102, Placebo
Drug
Lead sponsor
Xigen SA
Industry
Eligibility
18 Years and older
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Garden Grove, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 18, 2026, 5:56 AM EDT
Not listed Not applicable Interventional

Manual Small Incision Cataract Surgery Outcomes in an Educational Setting

NCT02277314
View directory record Official record
Conditions
Cataracts
Interventions
Manual Small Incision Cataract Surgery
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 18, 2026, 5:56 AM EDT
Recruiting Not applicable Interventional

Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens

NCT07006428
View directory record Official record
Conditions
Age Related Cataracts
Interventions
Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
Device
Lead sponsor
Argus Research Center, Inc.
Other
Eligibility
Not listed
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Torrance, California • Cape Coral, Florida • Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Phase 3 Interventional Results available

Loteprednol Etabonate Ophthalmic Ointment vs. Vehicle in the Treatment of Inflammation Following Cataract Surgery

NCT00645671
View directory record Official record
Conditions
Ocular Inflammation
Interventions
0.5% Loteprednol Etabonate Ophthalmic Ointment, Vehicle of Loteprednol Etabonate Ophthalmic Ointment
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Oct 18, 2026, 5:56 AM EDT
Terminated Phase 4 Interventional

Clinical Investigation of the Dextenza 0.4mg Intracanalicular Insert Delivery System Used in Cataract Surgery

NCT04687800
View directory record Official record
Conditions
Cataract
Interventions
Dextenza 0.4mg intracanalicular Insert, Durezol 0.05% Ophthalmic Emulsion
Drug
Lead sponsor
Cathleen McCabe MD
Other
Eligibility
18 Years to 90 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 18, 2026, 5:56 AM EDT
Terminated Not applicable Interventional Results available

Post Approval Study of the CyPass System

NCT03273907
View directory record Official record
Conditions
Primary Open-angle Glaucoma, Cataract
Interventions
CyPass Micro-Stent implanted with CyPass 241-S applier, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
20
States / cities
Phoenix, Arizona • Orange, California • Fort Collins, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Phase 4 Interventional Results available

ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)

NCT00684138
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power Intraocular Lens, ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2010 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent

NCT04629521
View directory record Official record
Conditions
Primary Open Angle Glaucoma, Cataract
Interventions
CyPass Micro-Stent, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
12
States / cities
Glendale, Arizona • Orange, California • Fort Collins, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational Results available

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

NCT05044793
View directory record Official record
Conditions
Glaucoma, Open-Angle
Interventions
OMNI® Surgical System
Device
Lead sponsor
Sight Sciences, Inc.
Industry
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Wichita, Kansas • Oklahoma City, Oklahoma • Jenkintown, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Not applicable Interventional Results available

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

NCT05985304
View directory record Official record
Conditions
Cataract, Corneal Astigmatism
Interventions
RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Rayner Intraocular Lenses Limited
Industry
Eligibility
22 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
9
States / cities
Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 18, 2026, 5:56 AM EDT
Withdrawn Not applicable Interventional

Hydrophilic Acrylic Intraocular Lens

NCT00708331
View directory record Official record
Conditions
Cataract Extraction
Interventions
2 HEMA Hydrophilic Acrylic Intraocular Lens
Device
Lead sponsor
EyeKon Medical, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
9
States / cities
Cape Coral, Florida • Fort Myers, Florida • Jacksonville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Oct 18, 2026, 5:56 AM EDT
Recruiting Not applicable Interventional

Hydrus® Microstent New Enrollment Post-Approval Study

NCT04553523
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Hydrus Microstent, Cataract surgery, Monofocal IOL
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
545 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
22
States / cities
Irvine, California • Sacramento, California • Loveland, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Phase 4 Interventional Results available

Oral Versus Intravenous Sedation for Ocular Procedures

NCT03246724
View directory record Official record
Conditions
Surgery, Sedation
Interventions
Triazolam, Midazolam, Microcrystalline Cellulose, Sodium chloride 0.9%
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational

Refractive Accuracy of Toric Intraocular Lens Implantation Using Digital Marking Compared to Conventional Marking

NCT07176897
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
Normal Toric IOL implantation with digital marking
Diagnostic Test
Lead sponsor
Colvard Kandavel Eye Center
Other
Eligibility
50 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 18, 2026, 5:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Vision and Quality of Life in the Nursing Home

NCT00347620
View directory record Official record
Conditions
Refractive Error, Cataract
Interventions
spectacles, Cataract Surgery
Device · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
17
States / cities
Alabaster, Alabama • Bessemer, Alabama • Birmingham, Alabama + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2010 · Synced Oct 18, 2026, 5:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)

NCT06325397
View directory record Official record
Conditions
Nuclear Cataract
Interventions
High Intraocular Pressure (IOP), Low Intraocular Pressure (IOP)
Other
Lead sponsor
Matthew Rauen
Other
Eligibility
Not listed
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
West Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 18, 2026, 5:56 AM EDT