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ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:02 AM EDT

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Showing 145–168 of 428 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cataract Extraction Clear all
Recruiting Phase 3 Interventional

Pilocarpine Use After Kahook Goniotomy

NCT03933631
View directory record Official record
Conditions
Glaucoma
Interventions
Pilocarpine, Prednisolone, Ofloxacin
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
30 Years to 100 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 18, 2026, 8:02 AM EDT
Completed No phase listed Observational

Evaluation of the Aspheric ReSTOR IOL After Routine Cataract Extraction

NCT00720005
View directory record Official record
Conditions
Cataract
Interventions
Aspheric Acrysof ReSTOR intraocular lens
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 4, 2010 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

NCT06506669
View directory record Official record
Conditions
Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions
Oral sedation, Placebo
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

EYEFILL® C. -US Viscoelastic Clinical Investigation

NCT02024711
View directory record Official record
Conditions
Cataract
Interventions
EYEFILL® C.-US Viscoelastic, Healon® Viscoelastic (CONTROL)
Device
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
22 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
8
States / cities
Phoenix, Arizona • Redding, California • Cape Coral, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 18, 2026, 8:02 AM EDT
Terminated No phase listed Observational

Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy

NCT02875704
View directory record Official record
Conditions
Stargardt Disease, Diabetic Retinopathy, Macular Degeneration (Age Related)
Interventions
Anterior Chamber (AC) Tap
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 4 Interventional

DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses

NCT04479748
View directory record Official record
Conditions
Cataract
Interventions
Dexamethasone, Prednisolone Acetate 1% Oph Susp
Drug
Lead sponsor
Prism Vision Group
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Vineland, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 18, 2026, 8:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes

NCT07227714
View directory record Official record
Conditions
Cataract Surgery, Eye Care, Glasses, Primary Eye Care, Vision Center, Eyecare Visits
Interventions
Establishment of a vision center
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
150,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 2 Interventional Results available

Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery

NCT06164743
View directory record Official record
Conditions
Inflammation
Interventions
VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, Vehicle
Drug
Lead sponsor
VivaVision Biotech, Inc
Industry
Eligibility
21 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
10
States / cities
Inglewood, California • Petaluma, California • Rancho Cordova, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Postmarket Study of an Intraocular Lens Power Selection System

NCT03579433
View directory record Official record
Conditions
Cataract
Interventions
ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
9
States / cities
Mt. Dora, Florida • Panama City, Florida • Poughkeepsie, New York + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 3 Interventional Results available

Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

NCT01591161
View directory record Official record
Conditions
Cataract, Inflammation, Surgery
Interventions
Mapracorat, Placebo
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 3 Interventional

ReSure Sealant Pivotal Study

NCT01498224
View directory record Official record
Conditions
Cataract Surgery Incision Leak
Interventions
ReSure Sealant, Sutures
Device · Procedure
Lead sponsor
Ocular Therapeutix, Inc.
Industry
Eligibility
22 Years and older
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 4 Interventional

Dexmedetomidine vs. Propofol for Cataract Surgery

NCT00786370
View directory record Official record
Conditions
Cataract
Interventions
dexmedetomidine, Propofol, Dexemedetomidine
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 10, 2012 · Synced Oct 18, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional

HUD Surgical Guidance for Toric Alignment

NCT07325188
View directory record Official record
Conditions
Cataract and IOL Surgery
Interventions
Cassini Guidance
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Not applicable Interventional

Cataract Removal and Alzheimer's Disease

NCT00921297
View directory record Official record
Conditions
Cataracts, Alzheimer's Disease
Interventions
Immediate Cataract Surgery
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
50 Years to 90 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2017 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 3 Interventional Results available

Clinical Endpoint Study of Nepafenac 0.3% Opthalmic Suspension

NCT03499873
View directory record Official record
Conditions
Cataract
Interventions
Nepafenac 0.3% Oph Susp, Placebos, Nepafenac 0.3% Oph Susp (reference)
Drug
Lead sponsor
Actavis Inc.
Industry
Eligibility
18 Years and older
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 18, 2026, 8:02 AM EDT
Enrolling by invitation No phase listed Observational

Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty

NCT07073937
View directory record Official record
Conditions
Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty, Intraocular Pressure (IOP), Cataract Surgery, Surgical Technique, Minimally Invasive Surgical Technique, Glaucoma
Interventions
Retrospective chart review
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 18, 2026, 8:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of RTVue in Corneal Measurement

NCT01220193
View directory record Official record
Conditions
Normal Cornea, Post Laser Refractive Surgery, Cornea Pathology, Cataract Surgery
Interventions
Not listed
Lead sponsor
Optovue
Industry
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
San Diego, California • Latham, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2011 · Synced Oct 18, 2026, 8:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluate Performance of Callisto Eye vs. Wavetec AnalyzOR

NCT06216067
View directory record Official record
Conditions
Cataract
Interventions
CALLISTO eye, Wavetec AnalyzOR
Device
Lead sponsor
Chesapeake Eyecare and Laser Center, LLC
Other
Eligibility
55 Years to 87 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 18, 2026, 8:02 AM EDT
Completed No phase listed Observational

Analysis of Eye Tissue

NCT00001224
View directory record Official record
Conditions
Eye Disease, Inflammation, Uveitis
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1987 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA

NCT05148507
View directory record Official record
Conditions
Cataract, Dry Eye Syndromes, Cataract Senile, Dry Eye
Interventions
PROKERA
Device
Lead sponsor
Jeff Wongskhaluang
Other
Eligibility
18 Years to 100 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Olathe, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 18, 2026, 8:02 AM EDT
Completed Phase 4 Interventional

Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial

NCT01279031
View directory record Official record
Conditions
Cataracts, Astigmatism
Interventions
Abbott WHITESTAR Signature System with Ellips Transversal Ultrasound, Alcon Infiniti wiht the OZIL Torsional Handpiece
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2012 · Synced Oct 18, 2026, 8:02 AM EDT
Terminated Phase 4 Interventional Results available

Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety

NCT00928772
View directory record Official record
Conditions
Anxiety
Interventions
CRANIAL ELECTROTHERAPY (Alpha Stim) + SHAM MIDAZOLAM, MIDAZOLAM + SHAM ELECTRODES SIMULATING CRANIAL ELECTROTHERAPY, NO SEDATION WITH SHAM CRANIAL ELECTROSTIMULATION AND PLACEBO VERSED
Device · Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
50 Years to 90 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 18, 2026, 8:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Flomax Study for Floppy Iris Syndrome

NCT01252472
View directory record Official record
Conditions
Floppy Iris Syndrome
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Male only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 18, 2026, 8:02 AM EDT