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ClinicalTrials.gov public records Last synced Oct 1, 2026, 10:23 PM EDT

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Showing 25–48 of 61 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cataract surgery and IOL implantation Clear all
Completed Not applicable Interventional Results available

A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)

NCT03274986
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional

An Assessment of Residual Spherical Aberration, Postoperative Total High Order Aberrations, and Functional Vision Correlation Following Intraocular Lens (IOL) Implantation

NCT01190631
View directory record Official record
Conditions
Cataracts
Interventions
Acrysof IQ (SN60WF) IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Results available

Dropless vs. Standard Drops Contralateral Eye Study

NCT02515045
View directory record Official record
Conditions
Cataract
Interventions
TriMoxiVanc, Moxifloxacin HCl 0.5%, Ilevro, Prednisolone acetate 1%
Drug
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Bloomington, Minnesota • Stillwater, Minnesota • Garden City, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Postmarket Study of an Intraocular Lens Power Selection System

NCT03579433
View directory record Official record
Conditions
Cataract
Interventions
ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
9
States / cities
Mt. Dora, Florida • Panama City, Florida • Poughkeepsie, New York + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional

A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)

NCT01045733
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
AcrySof IQ Toric IOL, AcrySof IQ Aspheric IOL, Limbal Relaxing Incision (LRI)
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 1, 2026, 10:23 PM EDT
Terminated Not applicable Interventional Results available

A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.

NCT05396599
View directory record Official record
Conditions
Cataract
Interventions
Model DIU, Model DFW, Model ZCT
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Los Angeles, California • Orange, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 1, 2026, 10:23 PM EDT
Completed No phase listed Observational

Association Between Light Spectrum and Survival After Cataract Surgery

NCT04187157
View directory record Official record
Conditions
Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma, Age Related Macular Degeneration
Interventions
Blue-light filtering intraocular lens, Conventional intraocular lens
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
10,192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Oct 1, 2026, 10:23 PM EDT
Active, not recruiting Not applicable Interventional

A Prospective Study Comparing Visual Outcomes and Patient Satisfaction Following Implantation of the Clareon PanOptix Versus Tecnis Odyssey IOL in Patients Undergoing Cataract Surgery.

NCT07768475
View directory record Official record
Conditions
Cataracts
Interventions
Intraocular Lens Implant
Device
Lead sponsor
Nvision Laser Eye Centers
Industry
Eligibility
Not listed
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Rowland Heights, California • Poughkeepsie, New York • Hurst, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 1, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery

NCT07155057
View directory record Official record
Conditions
Dry Eye Disease (DED)
Interventions
Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert

NCT04465864
View directory record Official record
Conditions
Glaucoma, Primary Open Angle, Cataract
Interventions
Intracanalicular Dexamethasone, 0.4 mg insert
Drug
Lead sponsor
Wolstan and Goldberg Eye Associates
Network
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Clareon Toric vs Eyhance Toric

NCT05481125
View directory record Official record
Conditions
Cataract, Aphakia
Interventions
Clareon IOL, Clareon Toric IOL, Eyhance IOL, Eyhance Toric IOL, Phacoemulsification surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Poughkeepsie, New York • Brecksville, Ohio • Mt. Pleasant, South Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs

NCT03733730
View directory record Official record
Conditions
Aphakia, Presbyopia, Astigmatism
Interventions
ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
2,449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Dothan, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 1, 2026, 10:23 PM EDT
Terminated Phase 4 Interventional

Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing

NCT01249144
View directory record Official record
Conditions
Cataract
Interventions
Intraocular Lens (IOL)
Device
Lead sponsor
Lenstec Incorporated
Industry
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tarpon Springs, Florida
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Oct 1, 2026, 10:23 PM EDT
Active, not recruiting No phase listed Observational

A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma

NCT06615661
View directory record Official record
Conditions
Primary Open Angle Glaucoma (POAG)
Interventions
C-Rex Instrument
Device
Lead sponsor
Iantrek, Inc.
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
6
States / cities
Cape Coral, Florida • DeLand, Florida • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional

A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00

NCT01105585
View directory record Official record
Conditions
Cataracts
Interventions
Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL, AcrySof Natural IQ (SN60WF) IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Phase 4 Interventional

Comparison of Visual Outcomes and Patient Satisfaction After Cataract Surgery and Implantation of ReSTOR and ReZoom IOLs

NCT00366587
View directory record Official record
Conditions
Cataract Extraction
Interventions
Cataract surgery and IOL implantation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 1, 2026, 10:23 PM EDT
Not listed Not applicable Interventional

Astigmatism Management With Iris-registration Guided Corneal Relaxing Incisions or Toric IOLs During Cataract Surgery

NCT05561296
View directory record Official record
Conditions
Astigmatism, Cataract
Interventions
Femtosecond laser assisted cataract surgery with astigmatism management
Procedure
Lead sponsor
Kenneth J Rosenthal
Other
Eligibility
18 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2022 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Phase 2 Interventional

Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery

NCT03180255
View directory record Official record
Conditions
Cataract, Anterior Chamber Inflammation, Pain, Postoperative
Interventions
Dexamethasone phosphate, Placebo
Combination Product · Other
Lead sponsor
Eyegate Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Oct 1, 2026, 10:23 PM EDT
Withdrawn Phase 4 Interventional

Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL

NCT00760058
View directory record Official record
Conditions
Cataract
Interventions
AcrySof® IQ IOL, Tecnis® Aspheric intraocular lens, Akreos® MI60 intraocular lens
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 1, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens

NCT07006428
View directory record Official record
Conditions
Age Related Cataracts
Interventions
Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
Device
Lead sponsor
Argus Research Center, Inc.
Other
Eligibility
Not listed
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Torrance, California • Cape Coral, Florida • Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 1, 2026, 10:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
View directory record Official record
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 1, 2026, 10:23 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study

NCT01191515
View directory record Official record
Conditions
Patients Implanted With Monofocal Intraocular Lens
Interventions
Monofocal Intraocular Lenses
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Williamsburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Phase 1Phase 2 Interventional

OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)

NCT02571556
View directory record Official record
Conditions
Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
Interventions
Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
Drug
Lead sponsor
Eyegate Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 1, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)

NCT01539239
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Hydrus Aqueous Implant, Cataract surgery
Device · Procedure
Lead sponsor
Ivantis, Inc.
Industry
Eligibility
45 Years and older
Enrollment
1,143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
26
States / cities
Phoenix, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2021 · Synced Oct 1, 2026, 10:23 PM EDT