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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cereal Refined grain Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Potatoes on Markers of Cardiometabolic Health

NCT03495284
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Interventions
Potato-based side dish, Refined grain-based
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
25 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Sep 27, 2026, 2:01 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Metabolomics-Driven Insights Into Ultra-Processed Foods

NCT07717970
View directory record Official record
Conditions
Diet, Food and Nutrition
Interventions
UPF Test Diet A: Starchy, refined grains, UPF Test Diet B: Meat, fish, and bread products, UPF Diet C: Dairy products, including cheese and cream
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Wholegrain Diet on Body Composition and Energy Balance

NCT01411540
View directory record Official record
Conditions
Overweight, Obesity, Pre-diabetic
Interventions
Whole grains
Dietary Supplement
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Diet on Pregnancy Outcome and Child Obesity

NCT03232762
View directory record Official record
Conditions
Pregnancy Related, Diet Modification, Obesity, Hypertension, Pre-Eclampsia, Blood Pressure, Breast Feeding, Birth Weight
Interventions
Refined Grains, Whole Grains
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
303 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Sep 27, 2026, 2:01 PM EDT
Not listed Not applicable Interventional

Healthy Heart Score Intervention In the Primary Care Setting

NCT03482427
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Healthy Heart Score
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 27, 2026, 2:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Personalized GI Motility Responses to Diet

NCT06386471
View directory record Official record
Conditions
Nutritional and Metabolic Diseases, Gastrointestinal Dysfunction, Cardiovascular Diseases, Dysbiosis
Interventions
Whole grain rye bread, Refined grain rye bread
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 63 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional

Grains Reduce Adiposity and Improve Nutrition Study

NCT00924521
View directory record Official record
Conditions
Metabolic Syndrome, Insulin Resistance
Interventions
Whole grain diet, Refined grain
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
35 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 27, 2026, 2:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn

NCT07767162
View directory record Official record
Conditions
Healthy Adult Females, Healthy Adult Males
Interventions
Whole-Grain Corn, Refined Corn
Dietary Supplement
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
25 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 27, 2026, 2:01 PM EDT
Recruiting Not applicable Interventional

The GRoceries Aimed at Increasing Nutrition Study

NCT07167004
View directory record Official record
Conditions
Type 2 Diabetes, Type II Diabetes Mellitus, Type II Diabetes, Pre-diabetes, Pre-diabetic, Pre-diabetic State, Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes Mellitus, Type 2 Diabetes (T2DM)
Interventions
Marketing Nudges Only, Marketing Nudges + Dynamically Adapted Financial Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 70 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional

Effect of Whole Grain Diet on Insulin Sensitivity, Advanced Glycation End Products and Inflammatory Markers in Pre-diabetes

NCT01248286
View directory record Official record
Conditions
Diabetes, Prediabetes
Interventions
Whole grain rice, Refined grain rice
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Daily Grain Intake Study

NCT04104581
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Control Refined Grain Diet, Low Whole Grain Oat Diet, High Whole Grain Oat Diet, Low Whole Grain Wheat Diet, High Whole Grain Wheat Diet
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2020 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional

Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals With Type 2 Diabetes Mellitus

NCT04511325
View directory record Official record
Conditions
Type2 Diabetes, Cardiometabolic Syndrome, Arterial Stiffness, Overweight and Obesity
Interventions
Potato Regimen, Refined Grain Regimen
Other
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Sep 27, 2026, 2:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Health Effects of Grain Foods in Adults

NCT06339879
View directory record Official record
Conditions
High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar, Low Whole Grain and Low Sugar, Low Whole Grain and High Sugar
Interventions
High Whole Grain, Low Sugar, Low Whole Grain, Low Sugar, High Whole Grain, High Sugar, Low Whole Grain, High Sugar
Other
Lead sponsor
Purdue University
Other
Eligibility
21 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analysis of MicroBial Metabolites After Eating Refined Food

NCT04308473
View directory record Official record
Conditions
Dietary Habits
Interventions
Ultra-processed Food Meal, Whole Food Meal
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Beta-cryptoxanthin Bioavailability From Biofortified Maize in Humans

NCT02800408
View directory record Official record
Conditions
β-cryptoxanthin Bioavailability From Biofortified Maize in Humans
Interventions
Whole grain high-BCX maize, Refined grain high-BCX maize, Whole grain white maize
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 28 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Satiety Effects of the Combination of Egg and Whole Grains

NCT02272153
View directory record Official record
Conditions
Food Selection
Interventions
Egg refined grain, Egg Whole Grain, Cereal Refined grain
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Liking, Acceptability and Health Benefits of Grain Products

NCT01403857
View directory record Official record
Conditions
Food Preferences
Interventions
Whole grain foods, Refined grains
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Addition of Whole Grains to the Diets of Adults: A Study of Digestive Health and Natural Defenses

NCT01902394
View directory record Official record
Conditions
Digestive Health and Immune Function
Interventions
Whole grains, Refined grains
Other
Lead sponsor
Tufts University
Other
Eligibility
40 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Results available

Optimization of Adaptive Text Messages for Cancer Survivors (OATS II)

NCT05746195
View directory record Official record
Conditions
Colon Adenocarcinoma, Colorectal Carcinoma, Rectal Adenocarcinoma
Interventions
Dietary intervention via Text Messaging, Survey Administration, Nutrition Education
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Addition of Whole Grains to the Diets of Middle-school Children

NCT01094652
View directory record Official record
Conditions
Healthy
Interventions
Whole grain diet, Refined grain diet
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 15 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Sep 27, 2026, 2:01 PM EDT
Not listed Not applicable Interventional

Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome

NCT05500976
View directory record Official record
Conditions
Dietary Habits
Interventions
Semi-controlled dietary intervention - Western, Semi-controlled dietary intervention - MiniMed
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 69 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 27, 2026, 2:01 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Processing Responses of Grains (PRO-Grains) Study

NCT02186353
View directory record Official record
Conditions
Insulin Resistance, Cardiovascular Disease, Diabetes
Interventions
Partial feeding study
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 27, 2026, 2:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Whole Grains, Gastric Emptying and Glycemic Response

NCT03467659
View directory record Official record
Conditions
Obesity, Diabetes Mellitus, Type 2, Appetitive Behavior
Interventions
Cracked whole wheat porridge, Semolina wheat porridge, Whole wheat flour porridge, Refined wheat flour porridge, Refined wheat flour porridge,fine bran, Refined wheat flour porridge,coarse bran
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced Sep 27, 2026, 2:01 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour

NCT06662214
View directory record Official record
Conditions
Effect of Food
Interventions
Refined maize flour, Whole grain flour
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 27, 2026, 2:01 PM EDT