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Showing 1–24 of 457 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cessation Treatment Counseling Clear all
Terminated Phase 4 Interventional Results available

Mindfulness Based Smoking Cessation Among Cancer Survivors

NCT04038255
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Nicoderm C-Q Transdermal Product, Orientation session, Craving-to-Quit app, Two brief follow-up phone calls, Group MT sessions, Brief advice on quitting smoking, Self-help smoking cessation materials
Drug · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Miami, Florida • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Maintaining Abstinence in Chronic Cigarette Smokers - 1

NCT00087880
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Bupropion and NRT
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care

NCT05415761
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
iCanQuit, iCanQuit+Motiv8, Florida quit line
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
1,332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures

NCT03099811
View directory record Official record
Conditions
Asthma, Incentives, Tobacco Smoking
Interventions
Incentive plan, Smoking cessation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Years to 12 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 2 Interventional

Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation

NCT01484717
View directory record Official record
Conditions
Cigarette Smoking
Interventions
contingency management for smoking abstinence, transdermal nicotine, Telephone counseling
Behavioral · Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 19, 2017 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional

Women Engaging in Quitting Smoking Together (WE QUIT)

NCT02051803
View directory record Official record
Conditions
Smoking Cessation
Interventions
Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 30, 2015 · Synced Sep 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACT Lung Health Intervention: Phase Two

NCT06945120
View directory record Official record
Conditions
Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction
Interventions
ACT Lung Health Intervention
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional

Comprehensive Tobacco Cessation for Cancer Patients and Survivors

NCT05805722
View directory record Official record
Conditions
Tobacco Use Cessation, Cancer
Interventions
Behavioral counseling for tobacco cessation
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Results available

Contingency Management for Smoking in Substance Abusers

NCT00807742
View directory record Official record
Conditions
Substance Abuse
Interventions
Nicotine Replacement Treatment (NRT), Brief Advice, Contingency Management, Non-Contingent Reinforcement
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 22, 2026, 1:47 AM EDT
Not listed Not applicable Interventional

Smoking Cessation for People Living With HIV/AIDS

NCT01965405
View directory record Official record
Conditions
HIV, AIDS, Nicotine Dependence
Interventions
Bupropion, Brief Counseling, High-magnitude prize contingency management, Monitored support to quit smoking, No additional treatment, Prize contingency management for abstinence, Low intensity prize contingency management
Drug · Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 22, 2026, 1:47 AM EDT
Recruiting Phase 1Phase 2 Interventional

Overcoming Nicotine Dependence to Enable Quitting

NCT05513872
View directory record Official record
Conditions
Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence, Nicotine Withdrawal
Interventions
Nicotine Replacement Therapy (NRT) Sampling, Practice Quitting (PQ) Counseling, Motivational Interviewing (MI) Counseling
Drug · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Not listed Not applicable Interventional

Targeted Intervention for Bipolar Smokers

NCT01550029
View directory record Official record
Conditions
Nicotine Dependence, Bipolar Disorder
Interventions
Counseling/Healthy Lifestyle, Counseling/Managing Mood
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 4 Interventional Results available

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

NCT00666978
View directory record Official record
Conditions
Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Leukemia, Liver Cancer, Lung Cancer, Pancreatic Cancer, Tobacco Use Disorder
Interventions
smoking cessation intervention, bupropion hydrochloride, gene expression analysis, polymerase chain reaction, counseling intervention, educational intervention, psychosocial assessment and care
Behavioral · Drug · Genetic + 2 more
Lead sponsor
Lisa Sanderson Cox, PhD
Other
Eligibility
18 Years and older
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Kansas City, Kansas • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional

HCV-Smoking Cessation Study

NCT05466981
View directory record Official record
Conditions
Hepatitis C, Smoking Cessation
Interventions
Cognitive Behavioral Counseling
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 22, 2026, 1:47 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Increasing Access to Smoking Cessation and Smoke Free Home Services for Low-Income Pregnant Women in Northeast Texas

NCT05051345
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Informational Intervention, Media Intervention, Questionnaire Administration, Smoking Cessation Intervention, Survey Administration, Telephone-Based Intervention, Tobacco Cessation Counseling
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 4 Interventional Results available

BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study

NCT05683821
View directory record Official record
Conditions
Quitting Smoking, Smoking Cessation, Smoking, Cigarette
Interventions
Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral, Referral to Primary Care Provider, BREATHE 2 Cessation Study, Additional modalities to learn about and request treatment
Behavioral · Drug · Combination Product
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
12,376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Results available

Hospital-based Patient Navigation and Smoking Cessation

NCT03452371
View directory record Official record
Conditions
Smoking Cessation
Interventions
Patient Navigation, Enhanced Traditional Care
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 22, 2026, 1:47 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Step-up to Quit: Using Low-to-moderate Intensity Exercise for Reducing Smoking Cue Reactivity Among Low-income Smokers

NCT02220465
View directory record Official record
Conditions
Sedentary Lifestyle, Cigarette Smoking
Interventions
PA+ Smoking Cessation (LMPA), Standard Care Smoking Counseling (SCC)
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 59 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Smoking Cessation Treatment for Adult Women

NCT01422239
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Tailored treatment, Standard Treatment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 19, 2020 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional

Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster

NCT02538601
View directory record Official record
Conditions
Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
Interventions
CBT-A, CBT-S
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2015 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparison of Standard Versus Extended Nicotine Patch Therapy for Smoking Cessation

NCT00364156
View directory record Official record
Conditions
TOBACCO USE CESSATION
Interventions
Standard Patch Treatment, 24-weeks of nicotine patch
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
568 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Coping Skills Treatment for Smoking Cessation

NCT01061528
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transdermal Nicotine
Drug
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 22, 2026, 1:47 AM EDT
Not yet recruiting Phase 4 Interventional

Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment

NCT07809854
View directory record Official record
Conditions
Cigarette Smoking, Veterans
Interventions
Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling, Healthy Changes Counseling
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Proactive Outreach for Smokers in VA Mental Health

NCT01737281
View directory record Official record
Conditions
Smoking
Interventions
Proactive outreach, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
1,938 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
4
States / cities
Tampa, Florida • Minneapolis, Minnesota • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Sep 22, 2026, 1:47 AM EDT