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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cessation-Phase Counseling Clear all
Completed Phase 3 Interventional Results available

Smoking-Cessation and Stimulant Treatment (S-CAST)

NCT01077024
View directory record Official record
Conditions
Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
Interventions
Smoking-cessation treatment
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
538 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
12
States / cities
Tucson, Arizona • Rancho Cucamonga, California • Tarzana, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Early Phase 1 Interventional Results available

Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients

NCT01434342
View directory record Official record
Conditions
Lung Cancer, Tobacco Use Disorder, Breast Cancer, Colorectal Cancer, Prostate Cancer
Interventions
Nicotine Replacement Patch
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 2 Interventional Results available

Treatment of Smoking Among Individuals With PTSD

NCT00937235
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
Interventions
Varenicline, Medication Management Counseling, Prolonged Exposure
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Sep 2, 2026, 11:22 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digitally Enhanced Smoking Cessation for High Risk Smokers

NCT04691297
View directory record Official record
Conditions
Smoking, Smoking Cessation, Lung Cancer Screening, Smoking, Tobacco, Smoking Behaviors
Interventions
Escape, Standard Care
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
55 Years to 77 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 2, 2026, 11:22 PM EDT
Recruiting Not applicable Interventional

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

NCT06837220
View directory record Official record
Conditions
Nicotine Use Disorder, Smoking Cessation, Smoking Cessation Intervention
Interventions
Enhanced Courage to Quit
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 4 Interventional

The Long-Term Quitting (Smoking Cessation) Study

NCT02564315
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Mini-Lozenge for 11 Months, Preparation Phase Behavioral Reduction Counseling, Preparation Phase Recycling Counseling, Preparation Phase Control Treatment, Cessation Phase Supportive Counseling, Cessation Phase Skill Training Counseling, Cessation Phase Brief Information, Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 16, 2020 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV

NCT03289676
View directory record Official record
Conditions
HIV/AIDS
Interventions
Storytelling Narrative Intervention
Combination Product
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Results available

Treating Tobacco Dependence in Inpatient Psychiatry - 1

NCT00136812
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
stage-tailored intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional

NC Enhanced WISEWOMAN Project

NCT00288327
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Lifestyle behavior change program, Pamphlets
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 64 Years · Female only
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2009 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Results available

Trial on the Effectiveness of Mindfulness Training for Smokers

NCT01093599
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Quit Line plus MTS, Quit Line Only
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry

NCT00968513
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Brief Intervention, Extended Treatment, Usual Care
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
956 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
Berkeley, California • San Francisco, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Menstrual Phase and Smoking Cessation at a State Quitline

NCT03908320
View directory record Official record
Conditions
Menstrual Cycle
Interventions
Menstrual Cycle Timing, NRT Patch, Cessation Counseling
Other · Drug · Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 2, 2026, 11:22 PM EDT
Recruiting Not applicable Interventional

Contingency Management for Veteran Smokers Undergoing Major Elective Surgery

NCT06678672
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorder (SUD)
Interventions
Contingency Management (CM), Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 11:22 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment

NCT05732272
View directory record Official record
Conditions
Smoking Cessation
Interventions
Bupropion
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Results available

Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)

NCT00908882
View directory record Official record
Conditions
Tobacco Use Cessation, Post Traumatic Stress Disorders
Interventions
Motivation Interviewing Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 15, 2015 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional

Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD

NCT01990079
View directory record Official record
Conditions
PTSD, Smoking
Interventions
Bupropion, nicotine replacement therapy, Smoking cessation counseling, mobile contingency management, Stay Quit Coach
Drug · Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Exenatide for Smoking Cessation and Prevention of Weight Gain

NCT05610800
View directory record Official record
Conditions
Smoking Cessation, Weight Gain
Interventions
Exenatide 2 milligram (mg) Injection, Placebo, Nicotine patch, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 3 Interventional

Treating Tobacco Dependence in Adolescents With Co-occurring Psychiatric Disorders

NCT00618943
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
Tobacco Use Cessation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
San Bruno, California • San Francisco, California • San Mateo, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2011 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smoking Reduction and Cessation Interventions for Chinese

NCT00714532
View directory record Official record
Conditions
Smoking Cessation
Interventions
Expert System Only, Enhanced Expert System
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Not applicable Interventional Results available

Hospital-based Patient Navigation and Smoking Cessation

NCT03452371
View directory record Official record
Conditions
Smoking Cessation
Interventions
Patient Navigation, Enhanced Traditional Care
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Selegiline for Smoking Cessation - 1

NCT00439413
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Selegiline Transdermal Patch, Placebo, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
4
States / cities
College Park, Maryland • New Brunswick, New Jersey • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 2, 2026, 11:22 PM EDT
Terminated Phase 3 Interventional

S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery

NCT00032084
View directory record Official record
Conditions
Lung Cancer
Interventions
smoking cessation intervention, bupropion hydrochloride, nicotine, psychosocial assessment and care
Behavioral · Drug · Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
175
States / cities
Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 115 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2013 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 2Phase 3 Interventional Results available

PRecision Interventions for SMoking in the SCCS

NCT03521141
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Nicotine patch, Varenicline, Nicotine metabolism, Genetically-informed lung cancer risk score, NCI "Clearing the Air"
Drug · Genetic · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 31, 2020 · Synced Sep 2, 2026, 11:22 PM EDT
Completed Phase 4 Interventional Results available

A Comparative Effectiveness RCT of Optimized Cessation Treatments

NCT02301403
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, in-person counseling and quitline counseling, Preparation Nicotine Mini-Lozenges, Combination NRT (nicotine patch + nicotine mini-lozenges), Intensive In-Person Cessation Counseling, Extended Maintenance Counseling Calls, Automated Adherence Calls
Drug · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
623 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 2, 2026, 11:22 PM EDT