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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:54 AM EDT

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Showing 313–336 of 1,538 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenge Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Dose-finding Study of WS6788A, DS37-4 and H10407 Enterotoxigenic Escherichia Coli (ETEC) Challenge Strains

NCT00198796
View directory record Official record
Conditions
Diarrhea
Interventions
H10407
Biological
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 45 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Phase 2 Interventional

Virtual Environment Rehabilitation for Chronic Stroke

NCT01414686
View directory record Official record
Conditions
Stroke
Interventions
Commercially-Available Interactive Video Games
Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 23, 2026, 2:54 AM EDT
Active, not recruiting Not applicable Interventional

ATTUNE Revision System in the Revision Total Knee Arthroplasty Population

NCT03153475
View directory record Official record
Conditions
Revision Total Knee Arthroplasty
Interventions
ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
22 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
16
States / cities
San Diego, California • Denver, Colorado • Fort Collins, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Phase 3 Interventional

Adherence, Improvement Measure (AIM) System

NCT01252212
View directory record Official record
Conditions
Patient Compliance, AIDS
Interventions
SMS medication adherence, No SMS adherence reminder
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults

NCT03527173
View directory record Official record
Conditions
Dysentery, Bacillary
Interventions
S.sonnei vaccine, Placebo, S. sonnei 53G challenge strain
Biological · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 50 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MBSR Programs to Reduce Compassion Fatigue in Nurses

NCT06436469
View directory record Official record
Conditions
Compassion Fatigue
Interventions
Mindfulness-Based Stress Reduction (MBSR) Program
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Hollywood, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 23, 2026, 2:54 AM EDT
Recruiting Not applicable Interventional

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

NCT06413173
View directory record Official record
Conditions
Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment, Post Concussive Symptoms
Interventions
Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
Combination Product
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
San Diego, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Increased Fructose Ingestion on FGF-21 Levels in Humans

NCT03201549
View directory record Official record
Conditions
Fasting
Interventions
oral fructose challenge
Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 23, 2026, 2:54 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy

NCT07287033
View directory record Official record
Conditions
Peanut Allergies
Interventions
MY006 Low Dose, MY006 Mid Dose, MY006 High Dose, MY006 Selected Dose, Placebo (Vehicle)
Drug
Lead sponsor
Mabylon AG
Industry
Eligibility
12 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
9
States / cities
Little Rock, Arkansas • Aurora, Colorado • Colorado Springs, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Active, not recruiting Not applicable Interventional

Improving PCP Advance Care Planning for People With ADRD

NCT06565169
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Alzheimer's Disease (Incl Subtypes), Aging
Interventions
Primary Care Team Advance Care Planning With People with Alzheimer's Disease or a Related Dementia Training, Care as Usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 99 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Community Active and Healthy Families

NCT04414553
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Community Active and Healthy Families
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Aurora, Colorado • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of Human Rhinovirus Type 16 (HRV-16) Following Administration in the Nose of Healthy Adult Volunteers

NCT01466738
View directory record Official record
Conditions
Healthy
Interventions
HRV-16 (100 TCID50), HRV-16 (1000 TCID50)
Biological
Lead sponsor
Centocor Ortho Biotech Services, L.L.C.
Industry
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TAME Health: Testing Activity Monitors' Effect on Health

NCT02554435
View directory record Official record
Conditions
Physical Activity
Interventions
EAM, 5 A's counseling, Pedometer
Device · Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
55 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Galveston, Texas • League City, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Trial With Deltex Cardio in Elective Bowel Resection Patients

NCT01244685
View directory record Official record
Conditions
1 Fluid Management
Interventions
Deltex CardioQ Probe
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Expressive Interviewing Agents to Support Health-Related Behavior Change

NCT05949840
View directory record Official record
Conditions
Mental Stress
Interventions
Expressive Interviewing
Other
Lead sponsor
University of Michigan
Other
Eligibility
Not listed
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 23, 2026, 2:54 AM EDT
Withdrawn Not applicable Interventional

The Brain Ketone Body Challenge Imaging Study

NCT03204604
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Challenge A - low calorie Ensure®, Challenge B - Ensure® plus ketone esters (KE), PET Scan, Cognitive Testing - FCSRT, Story Recall, BVRT, CogState One Card Learning
Dietary Supplement · Procedure · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 23, 2026, 2:54 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

pH1N1 Blinded Challenge Study

NCT07110532
View directory record Official record
Conditions
Influenza
Interventions
A/Arkansas/08/2020 (pH1N1), Sham/Diluent (1X SPG+Arg+Gel)
Biological · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Interactive Obesity Treatment Approach for Obesity Prevention in Adults With Early Serious Mental Illness: iOTA-SMI

NCT03980743
View directory record Official record
Conditions
Obesity, Overweight, Severe Mental Disorder
Interventions
iOTA text messaging intervention, Health Education text messaging intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Miami, Florida • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Predictors of Response to Insomnia Treatments for Gulf War Veterans

NCT03208049
View directory record Official record
Conditions
Insomnia
Interventions
Behavioral Therapy (BT), Cognitive Therapy (CT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Palo Alto, California • Washington D.C., District of Columbia • East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills

NCT04518358
View directory record Official record
Conditions
Autism Spectrum Disorder, Intellectual Disability
Interventions
Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges
Behavioral
Lead sponsor
John T. Nosek
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Check-Up Online

NCT06161597
View directory record Official record
Conditions
Families of Middle School Students at Title 1 Schools
Interventions
Family Check-Up Online
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 16 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

VergeRx for Smokers Not Ready to Quit

NCT07693660
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
VergeRx, SmokefreeTXT, NRT Lozenge (Combination), Extended NRT Patch (16 weeks), Standard NRT Patch (8 weeks)
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
592 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2032
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dual Diagnosis Training Trial

NCT06238258
View directory record Official record
Conditions
Training Group
Interventions
SPECTROM Training
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 23, 2026, 2:54 AM EDT
Not listed Not applicable Interventional

A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis

NCT06350149
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Sugar Sweetened Beverages (SSB), Hi GI, Lo GI
Other
Lead sponsor
Emory University
Other
Eligibility
12 Years to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 23, 2026, 2:54 AM EDT