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ClinicalTrials.gov public records Last synced Oct 26, 2026, 8:31 AM EDT

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Showing 673–696 of 1,539 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenge Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Flexibility as a Biomarker of Adaptation to Diet and Exercise Challenges

NCT01987388
View directory record Official record
Conditions
Healthy Volunteers
Interventions
High Intensity Exercise, Low Intensity Exercise, High Carbohydrate Beverage, High Fat Beverage
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
22 Years to 35 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional

Evaluating Process of Change in Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for Depression

NCT06245096
View directory record Official record
Conditions
Depression
Interventions
Cognitive Behavioral Therapy, Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Autoimmune Basis for Postural Tachycardia Syndrome

NCT02725060
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, Tachycardia, Arrhythmias, Cardiac, Autonomic Nervous System Diseases, Orthostatic Intolerance, Cardiovascular Diseases, Primary Dysautonomias
Interventions
phenylephrine, isoproterenol, 25 micro-Ci of radiation, Posture study with blood samples, 24-hour heart rhythm and blood pressure monitoring, Quantitative Axonal Sudomotor Reflex Testing, Autonomic function tests, Rebreathing test, Assessment of splanchnic capacitance, microneurography
Drug · Radiation · Procedure + 1 more
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 26, 2026, 8:31 AM EDT
Recruiting Not applicable Interventional

A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment

NCT05189223
View directory record Official record
Conditions
Dependence, Opioid
Interventions
Brief, values based intervention for early buprenorphine treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional Results available

Coping Together After Breast Cancer

NCT03930797
View directory record Official record
Conditions
Breast Cancer
Interventions
Intimacy Enhancement, Living Healthy Together
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 26, 2026, 8:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptation of Critical Time Intervention for Young Adults With MH Challenges

NCT06102850
View directory record Official record
Conditions
Mental Disorder
Interventions
Critical Time Intervention for Young Adults with Mental Health conditions
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional Results available

A Study of Overcoming Social Determinants of Health

NCT05773313
View directory record Official record
Conditions
Social Determinants of Health (SDOH)
Interventions
The Open Table
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional Results available

Improving Treatment Outcomes for Suicidal Veterans With PTSD

NCT04690582
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Ptsd
Interventions
Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI), Narrative Assessment
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 26, 2026, 8:31 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility

NCT02767973
View directory record Official record
Conditions
Airway Inflammation, Allergic Asthma
Interventions
Wood Smoke Particles (WSP)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Secretin in Functional Dyspepsia and Healthy Subjects

NCT03617861
View directory record Official record
Conditions
Dyspepsia, Healthy
Interventions
Human Secretin, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 11, 2020 · Synced Oct 26, 2026, 8:31 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Physiological Chronobiome Modified by Age, Sex and Under Evoked Conditions

NCT04225442
View directory record Official record
Conditions
Healthy, Healthy Aging
Interventions
Fatty meal to challenge the physiological chronobiome in healthy young and old
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Active, not recruiting Not applicable Interventional

Mobile Video Interpretation to Optimize Communication Across Language Barriers

NCT05591586
View directory record Official record
Conditions
Limited English Proficiency
Interventions
Web based educational modules, mobile video interpreting (mVI) access
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
6,669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place

NCT03853148
View directory record Official record
Conditions
Pain, Chronic, Fatigue Syndrome, Chronic, Aging
Interventions
Otago, Gentle yogic breathing, Behavioral Activation, Caregiver Gentle yogic breathing
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2022 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of Bovine Milk Immunoglobulin Against CS17 and CsbD

NCT00524004
View directory record Official record
Conditions
Travelers' Diarrhea
Interventions
Anti-CsbD Bovine IgG, Placebo, Anti-CS17 Bovin IgG
Biological · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional

Trial With Deltex Cardio in Elective Bowel Resection Patients

NCT01244685
View directory record Official record
Conditions
1 Fluid Management
Interventions
Deltex CardioQ Probe
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 26, 2026, 8:31 AM EDT
Recruiting Phase 2 Interventional

Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose

NCT04278898
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
N-Acetylcysteine
Drug
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional

Resilience-Based Diabetes Self-Management Education (RB-DSME) for African Americans

NCT04282395
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Resilience-Based Diabetes Self-Management Education, Standard Diabetes Self-Management Education
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Gestational Diabetes Screening in the Gravid Obese Woman

NCT01864564
View directory record Official record
Conditions
Gestational Diabetes, Obesity
Interventions
Early Screen
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
962 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
Birmingham, Alabama • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional

Choosing Wisely: De-implementing Fall Prevention Alarms in Hospitals

NCT06089239
View directory record Official record
Conditions
Accidental Fall, Patient Safety, Hospital Acquired Condition, Clinical Alarms, Mentoring
Interventions
High Intensity Coaching, Low Intensity Coaching
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
20
States / cities
Downey, California • Mountain View, California • Sacramento, California + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Terminated Not applicable Interventional

Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy

NCT04763330
View directory record Official record
Conditions
Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
Interventions
Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Palo Alto, California • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Phase 4 Interventional Results available

Steroid Treatment for Hypereosinophilic Syndrome

NCT01524536
View directory record Official record
Conditions
Eosinophilia, Hypereosinophilic Syndrome, Leukocyte Disorder, Hematologic Diseases
Interventions
prednisone
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
7 Years to 100 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 26, 2026, 8:31 AM EDT
Terminated Early Phase 1 Interventional Results available

Screening Inhaled Allergen Challenge for Dermatophagoides Farinae

NCT03049111
View directory record Official record
Conditions
Asthma
Interventions
Der f
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Phase 1 Interventional Results available

Cockroach Nasal Allergen Challenge Pilot

NCT02710136
View directory record Official record
Conditions
Asthma, Cockroach Hypersensitivity
Interventions
Glycerinated German Cockroach Allergenic Extract
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
8 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Oct 26, 2026, 8:31 AM EDT
Completed Not applicable Interventional

Translating 3-Step Workout for Life in a Local Senior Living Community

NCT03095534
View directory record Official record
Conditions
Frail Elderly, Muscle Weakness
Interventions
3-Step Workout for Life
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
60 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 26, 2026, 8:31 AM EDT