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ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:55 AM EDT

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Showing 721–744 of 1,539 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenge Clear all
Terminated Phase 1 Interventional Accepts healthy volunteers

Evaluation Of PF-00572778 And Alprazolam On Naloxone Challenge In Healthy Subjects

NCT00580190
View directory record Official record
Conditions
Healthy
Interventions
alprazolam, Placebo, PF-00572778
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2009 · Synced Oct 26, 2026, 9:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer

NCT06307535
View directory record Official record
Conditions
Caregiver Burden, Caregiver Burnout, Caregiver Stress Syndrome
Interventions
Meaning-Centered Psychotherapy for Caregivers, Supportive Psychotherapy for Caregivers
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
8
States / cities
Miami, Florida • Basking Ridge, New Jersey • Middletown, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Pilot Influenza Challenge Study

NCT07063849
View directory record Official record
Conditions
Influenza
Interventions
A/Texas
Biological
Lead sponsor
Daniel Hoft, MD, PhD
Other
Eligibility
18 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 26, 2026, 9:55 AM EDT
Not listed Not applicable Interventional

Serious Games for Parkinson's Disease

NCT05551338
View directory record Official record
Conditions
Parkinson Disease, Parkinson
Interventions
Serious games
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional Results available

Take a Break (TAB): mHealth-assisted Skills Building Challenge for Unmotivated Smokers

NCT02973425
View directory record Official record
Conditions
Smoking Cessation
Interventions
Take a Break as an augmentation to NRT-sampling in Motivation Phase, NRT and mHealth assessment tool without feedback
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
4
States / cities
Worcester, Massachusetts • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Phase 3 Interventional Results available

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

NCT05555290
View directory record Official record
Conditions
Asthma
Interventions
PT027, PT007
Combination Product
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics

NCT02459327
View directory record Official record
Conditions
Infant Behavior, Child Behavior, Parenting, Child Rearing, Depression, Personal Satisfaction, Behavioral Symptoms, Social Control, Informal
Interventions
Video Interaction Project, Family Check Up
Behavioral
Lead sponsor
New York University
Other
Eligibility
0 Years and older
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 26, 2026, 9:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Web-based Professional Development for SMHPs in Evidence-Based Practices for Attention and Behavior Challenges

NCT05713331
View directory record Official record
Conditions
ADHD
Interventions
CLS-R
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 11 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2023 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional

Integrating Solution Focused Interventions in Integrated Care

NCT05838222
View directory record Official record
Conditions
Depression, Diabetes Mellitus, Hypertension, Anxiety Disorders
Interventions
Solution Focused Intervention, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Inflammation, Polyphenols, and Genetics

NCT01568827
View directory record Official record
Conditions
Overweight, Obese
Interventions
Blackraspberry Slurry
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
55 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Phase 3 Interventional Results available

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.

NCT00769886
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
Ketotifen/naphazoline, Ketotifen, Naphazoline, Vehicle
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
6 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
North Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 26, 2026, 9:55 AM EDT
Recruiting Not applicable Interventional

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

NCT05062369
View directory record Official record
Conditions
Alcohol Use Disorder, Addiction
Interventions
TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Recruiting Not applicable Interventional

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

NCT06686680
View directory record Official record
Conditions
Knee Osteoarthristis, ACL Injuries, Post-Traumatic
Interventions
extracorporeal shockwave therapy (ESWT), Sham Comparator
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional Results available

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

NCT04293341
View directory record Official record
Conditions
Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
Interventions
Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD, Cognitive Behavioral Therapy for Panic Disorder
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Phase 1 Interventional Results available

To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients

NCT02542605
View directory record Official record
Conditions
Migraine
Interventions
Erenumab, Placebo, PACAP-38 Challenge Agent
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional

Early Intervention Foster Care: A Prevention Trial

NCT00701194
View directory record Official record
Conditions
School Readiness, Developmental Delays
Interventions
Early Intervention Foster Care (EIFC)
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
3 Years to 6 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prehabilitation Using Aquatic Exercise

NCT02773745
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Aquatic Prehab
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Phase 3 Interventional Results available

PALISADE Follow-on Study (ARC004)

NCT02993107
View directory record Official record
Conditions
Peanut Allergy
Interventions
AR101
Biological
Lead sponsor
Aimmune Therapeutics, Inc.
Industry
Eligibility
4 Years to 55 Years
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
47
States / cities
Tucson, Arizona • Little Rock, Arkansas • Mission Viejo, California + 39 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Oct 26, 2026, 9:55 AM EDT
Completed Not applicable Interventional Results available

Positive Minds Strong Bodies Implementation

NCT04545593
View directory record Official record
Conditions
Depression, Anxiety, Physical Disability
Interventions
Positive Minds Strong Bodies Enhanced, Enhanced Usual Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older
Enrollment
427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Influenza Human Challenge Model

NCT05332899
View directory record Official record
Conditions
Influenza
Interventions
Influenza Virus Type A H3N2 Challenge
Biological
Lead sponsor
Emory University
Other
Eligibility
18 Years to 49 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Active, not recruiting Not applicable Interventional

Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity

NCT05429736
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Spasticity, Muscle
Interventions
Motor Skill Training (MST), Transcutaneous Spinal Stimulation (TSS)
Behavioral · Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Recruiting Not applicable Interventional

Virtual Reality Based Rehabilitation After Ischemic Stroke

NCT06401564
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Virtual Reality Therapy
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 26, 2026, 9:55 AM EDT
Completed No phase listed Observational

Voices Of Individuals: Challenges and Experiences Of bvFTD

NCT04060082
View directory record Official record
Conditions
Frontotemporal Dementia, Frontotemporal Degeneration, Frontotemporal Dementia, Behavioral Variant, FTD
Interventions
Telephone Interview
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Baltimore, Maryland • Bethesda, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 26, 2026, 9:55 AM EDT
Withdrawn Not applicable Interventional

Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 2)

NCT06114862
View directory record Official record
Conditions
Stigma, Social, Mental Health Issue
Interventions
Stigma-reduction intervention
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 26, 2026, 9:55 AM EDT