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ClinicalTrials.gov public records Last synced Oct 28, 2026, 9:08 PM EDT

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Showing 1081–1104 of 1,541 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenge Clear all
Completed Not applicable Interventional Accepts healthy volunteers

HARP-Project 1 Cognitive Training

NCT03293823
View directory record Official record
Conditions
Aging, Social Isolation
Interventions
VSOP training, MLA control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Fairport, New York • Pittsford, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae

NCT05294588
View directory record Official record
Conditions
Gonorrhea Male
Interventions
Cefixime, Ceftriaxone, Ciprofloxacin, Neisseria gonorrhoeae strain FA1090, Meningococcal Group B Vaccine, Influenza Vaccine, Tetanus-diptheria Vaccine
Drug · Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma

NCT06270576
View directory record Official record
Conditions
Asthma; Eosinophilic, Asthma
Interventions
Lipopolysaccharides
Drug
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 28, 2026, 9:08 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Glutathione vs. Curcumin Clinical Trial

NCT02848417
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Curcumin, Glutathione, Placebo
Drug · Other
Lead sponsor
South Florida Veterans Affairs Foundation for Research and Education
Federal
Eligibility
35 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Prevention of Alcohol Intolerance

NCT01845220
View directory record Official record
Conditions
Alcohol Sensitivity
Interventions
Broccoli Sprout Extract, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 29, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Active, not recruiting Not applicable Interventional

A Novel Program Using Ride-on Toys to Improve Upper Extremity Function in Children With Hemiplegia

NCT06579027
View directory record Official record
Conditions
Hemiplegia, Cerebral Palsy, Children, Only
Interventions
SPEED Training, CRAFT Training
Device · Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
3 Years to 8 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of Mental Health and Relationships

NCT06534827
View directory record Official record
Conditions
Mental Health
Interventions
Great Life Mentoring
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
9 Years to 16 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional

A Health and Wellness Lifestyle Program to Support Community-Dwelling Persons With Traumatic Brain Injury

NCT04288258
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Telehealth-Based Health and Wellness Program (POWERS-TBI)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Not listed
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Phase 2 Interventional

An Integrated Intervention Using a Pill Ingestible Sensor System

NCT06480578
View directory record Official record
Conditions
HIV/AIDS, Medication Adherence, Social Determinants of Health (SDOH)
Interventions
ISS-SBDOH arm
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Norwalk Vaccine Study

NCT00973284
View directory record Official record
Conditions
Acute Gastroenteritis, Norwalk Virus Infection
Interventions
Norwalk VLP vaccine, mannitol and sucrose, Norwalk virus
Biological
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 50 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
3
States / cities
Baltimore, Maryland • Cincinnati, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Phase 4 Interventional

Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food Allergy

NCT07845552
View directory record Official record
Conditions
Food Allergy
Interventions
Omalizumab
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
1 Year to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Well-being Web-based Intervention

NCT01586949
View directory record Official record
Conditions
Focus of Study: Healthy Individuals
Interventions
Daily Challenge
Behavioral
Lead sponsor
MeYou Health, LLC
Industry
Eligibility
18 Years and older
Enrollment
1,503 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 28, 2026, 9:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

ThriveCircles for Well-Being at CU SOM

NCT07366333
View directory record Official record
Conditions
Well-being at Work
Interventions
ThriveCircle Peer-Led Well-Being Groups
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Phase 1 Interventional

A Study To Determine The Effect Of SB-480848 On Asthma

NCT00368576
View directory record Official record
Conditions
Atherosclerosis
Interventions
SB 480848, tablets
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
4
States / cities
Cypress, California • Normal, Illinois • North Dartmouth, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Oct 28, 2026, 9:08 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions

NCT06932289
View directory record Official record
Conditions
NAFLD (Nonalcoholic Fatty Liver Disease)
Interventions
Mediterranean diet (MED), high-fat/low carb diet (HF/LC), and low-fat diet (LF), The integrated sweat sensor and vascular sensor (wearable), continuous glucose monitor (CGM)
Dietary Supplement · Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella Infection: Phase IIa

NCT00866476
View directory record Official record
Conditions
Shigella
Interventions
CVD 1208S, a Shigella flexneri 2a live, oral vaccine, Placebo
Biological · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Repeated Challenge of Insufficient Sleep: Endothelial Effects

NCT01523535
View directory record Official record
Conditions
Repeated Short Sleep Schedule
Interventions
repeated cycles of short sleep
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
25 Years to 55 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

A/Texas Flu Challenge

NCT06753474
View directory record Official record
Conditions
Influenza
Interventions
Influenza Virus influenza A H3N2 strain
Biological
Lead sponsor
Emory University
Other
Eligibility
18 Years to 49 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Contextualizing & Responding to HIV Risk Behaviors

NCT03300908
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Project ADHERE, MACE
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Detection of Bovine and Soy Proteins in Human Milk

NCT04851340
View directory record Official record
Conditions
Microbiome, Stress, Food Allergy in Infants
Interventions
Cow's Milk, Soy Milk
Other
Lead sponsor
University of Idaho
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Leading Healthy Eating and Activity Promotion Program

NCT06868524
View directory record Official record
Conditions
Cancer Survivor, Cancer, Oncology
Interventions
LEAP Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effect of Nasaleze on Nasal Challenge With Allergen

NCT01723397
View directory record Official record
Conditions
Allergic Rhinitis
Interventions
Nasaleze Spray, Placebo spray, Allergen
Drug · Other · Biological
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 2, 2017 · Synced Oct 28, 2026, 9:08 PM EDT
Recruiting Not applicable Interventional

BOLSTER: Learning New Skills to Thrive

NCT06936878
View directory record Official record
Conditions
Gastrointestinal Cancer, Gynecologic Cancer, Advanced Cancer
Interventions
BOLSTER Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 28, 2026, 9:08 PM EDT
Completed Not applicable Interventional Results available

Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury

NCT04073225
View directory record Official record
Conditions
Traumatic Brain Injury, Dementia Alzheimers, Military Activity
Interventions
MindPod Dolphin, 10 Keys to Healthy Aging
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 28, 2026, 9:08 PM EDT