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ClinicalTrials.gov public records Last synced Oct 29, 2026, 9:41 AM EDT

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Showing 1105–1128 of 1,541 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenge Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Youth to Text or Telehealth for Engagement in HIV Care

NCT03681145
View directory record Official record
Conditions
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
Interventions
Counselor delivered telehealth intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 29, 2026, 9:41 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Empiric Quinidine for Asymptomatic Brugada Syndrome

NCT00789165
View directory record Official record
Conditions
Arrhythmia
Interventions
quinidine, no therapy
Drug
Lead sponsor
International Registry of Asymptomatic Brugada Syndrome
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 29, 2026, 9:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cumulative Irritation Patch Test

NCT01842711
View directory record Official record
Conditions
Allergy, Irritation, Sensitization
Interventions
Not listed
Lead sponsor
Chattem, Inc.
Industry
Eligibility
16 Years to 79 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Fairfield, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Oct 29, 2026, 9:41 AM EDT
Active, not recruiting Phase 2 Interventional

Improving Mental Health Among the LGBTQ+ Community

NCT05540067
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Acceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU)
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Enrolling by invitation Not applicable Interventional

Sampling Therapeutic Effects and Progress in Cerebral Palsy (STEP-CP)

NCT07752030
View directory record Official record
Conditions
Cerebral Palsy (CP)
Interventions
Physical Therapy Gait Training
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
16 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Coffee Roasting on Blood Sugar Levels in Healthy Humans

NCT05119153
View directory record Official record
Conditions
Hyperglycemia
Interventions
Placebo Comparator, Light Roasted Coffee, Medium Roasted Coffee, Dark Roasted Coffee
Dietary Supplement
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2021 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional

Study of Safety and Effectiveness of PoNS Device to Treat Chronic Balance Deficit Due to Traumatic Brain Injury (TBI)

NCT02429167
View directory record Official record
Conditions
Traumatic Brain Injury, Chronic Balance Disorder
Interventions
Cranial nerve non-invasive neuromodulation via PoNS device, Sham PoNS device
Device
Lead sponsor
Helius Medical Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Orlando, Florida • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 29, 2026, 9:41 AM EDT
Enrolling by invitation Phase 1 Interventional Accepts healthy volunteers

Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 Influenza

NCT07215871
View directory record Official record
Conditions
Influenza Infection, Infections, Respiratory Virus Infections, Respiratory Tract Infections, RNA Viruses, Orthomyxoviridae Infections, Viral Diseases
Interventions
A/Mallard/Ohio-99/MM4/1989 H10N7
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 55 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Results available

Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke

NCT03215771
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke
Interventions
MyoPro Motion-G, Motor Learning-Based Therapy
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

MIrabegron and Physiological Function in Cold Environments

NCT05990387
View directory record Official record
Conditions
Resting Energy Expenditure, Thermogenesis, Brown Adipose Tissue
Interventions
Mirabegron, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Results available

Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis

NCT04187092
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
KneeBright Group, Standard Rehabilitation group
Other
Lead sponsor
University of Virginia
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 29, 2026, 9:41 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge

NCT00671593
View directory record Official record
Conditions
Atopic Asthma, Healthy
Interventions
House Dust Mite, Diluent
Biological
Lead sponsor
John Sundy
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2013 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Results available

A Family-centered Intervention for Acutely-ill Persons With Dementia

NCT03046121
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Family-centered Function-focused Care (Fam-FFC)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Lancaster, Pennsylvania • Philadelphia, Pennsylvania • West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants

NCT04532164
View directory record Official record
Conditions
Dermatitis, Photoallergic
Interventions
Butenafine HCl 1% (BAY1896425) - Induction Phase, Butenafine HCl 1% (BAY1896425) - Challenge Phase
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Fairfield, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vision-based Speed of Processing Cognitive Training and Mild Cognitive Impairment

NCT02559063
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Vision-based speed of processing training, Mental leisure activities
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 29, 2026, 9:41 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

NCT00595491
View directory record Official record
Conditions
Asthma
Interventions
Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage
Biological
Lead sponsor
Benjamin Medoff
Other
Eligibility
18 Years to 50 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Phase 4 Interventional Results available

Identifying Treatments to Motivate Smokers to Quit

NCT01122238
View directory record Official record
Conditions
Smoking, Smoking Cessation, Motivation, Nicotine Dependence
Interventions
Nicotine Patch, Nicotine Gum, Motivational Interviewing, Smoking Reduction, No Intervention, Nicotine Patch + Nicotine Gum
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Oct 29, 2026, 9:41 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

NCT02639299
View directory record Official record
Conditions
Malaria
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 50 Years
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Opportunities in Outpatient Care

NCT03163225
View directory record Official record
Conditions
Outpatient Care
Interventions
Not listed
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
7 Years and older
Enrollment
1,027 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
9
States / cities
Murray, Utah • Riverton, Utah • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Phase 3 Interventional Results available

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

NCT05555290
View directory record Official record
Conditions
Asthma
Interventions
PT027, PT007
Combination Product
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reaching for Equity in Sleep Apnea Treatment (REST) Study

NCT04209985
View directory record Official record
Conditions
Sleep Apnea
Interventions
Health coaching
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Active, not recruiting Not applicable Interventional

A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship

NCT05448560
View directory record Official record
Conditions
Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice, Adherence, Patient
Interventions
Multi-level Intervention of shared model of survivorship care, Comparison Group
Behavioral · Other
Lead sponsor
Georgetown University
Other
Eligibility
2 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Long Beach, California • Denver, Colorado • Hackensack, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 29, 2026, 9:41 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

GI-Challenge Study for Gastroparesis Patients and Healthy Controls

NCT03896126
View directory record Official record
Conditions
Gastroparesis
Interventions
Observational
Other
Lead sponsor
Stanford University
Other
Eligibility
20 Years to 49 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 29, 2026, 9:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

BLYS and IFN in SLE

NCT00611611
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
fluzone, pneumovax
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 28, 2011 · Synced Oct 29, 2026, 9:41 AM EDT