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ClinicalTrials.gov public records Last synced Oct 18, 2026, 11:29 AM EDT

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Showing 1–24 of 1,537 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Challenges Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin as Adjunctive Treatment of Schizophrenia

NCT01568528
View directory record Official record
Conditions
Schizophrenia
Interventions
Oxytocin, Placebo, Control
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Phase 2 Interventional

Mucosal and Systemic Immunity After Viral Challenge of Healthy Volunteers Vaccinated With Inactivated Influenza Vaccine Via the Intranasal Versus Intramuscular Route

NCT03845231
View directory record Official record
Conditions
Influenza
Interventions
Flucelvax(R), Human Challenge virus
Biological · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 55 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

NCT04134767
View directory record Official record
Conditions
Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis), Overdose, Drug, Opioid Use
Interventions
Health Linkage, Overdose Education
Behavioral
Lead sponsor
April M Young
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 18, 2026, 11:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

BLYS and IFN in SLE

NCT00611611
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
fluzone, pneumovax
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 28, 2011 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Phase 3 Interventional Results available

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis

NCT05579730
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
Brimonidine tartrate 0.025%/ketotifen fumarate 0.035%, Brimonidine Tartrate 0.025%, Ketotifen Fumarate 0.035%, Vehicle
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
10 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Phoenix, Arizona • Andover, Massachusetts • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional

Aging and Family Outcomes in Supportive Care of Advanced Cancer Patients

NCT00106067
View directory record Official record
Conditions
Aging, Neoplasms
Interventions
coping and communication support (CCS) intervention
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 18, 2026, 11:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Opportunistic Screening for Prediabetes and Early Diabetes in Primary Care

NCT00787839
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Prediabetic State
Interventions
Glucose challenge test, Glucose tolerance test
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
1,939 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional

Contextualizing & Responding to HIV Risk Behaviors

NCT03300908
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Project ADHERE, MACE
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Phase 3 Interventional Results available

A Multi-Center, Evaluation of the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle

NCT01881113
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
AC-170 0.24%, AC-170 0%
Drug
Lead sponsor
Aciex Therapeutics, Inc.
Industry
Eligibility
10 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 9, 2017 · Synced Oct 18, 2026, 11:29 AM EDT
Completed No phase listed Observational

Pain Rating Challenges and Patterns

NCT06115278
View directory record Official record
Conditions
Chronic Pain
Interventions
survey
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 110 Years
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional

Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis

NCT03949296
View directory record Official record
Conditions
Insomnia Chronic, Multiple Sclerosis
Interventions
Mindfulness Intervention, Sleep Hygiene
Behavioral
Lead sponsor
Griffin Hospital
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional

Evaluating Process of Change in Cognitive Behavioral Therapy and Acceptance and Commitment Therapy for Depression

NCT06245096
View directory record Official record
Conditions
Depression
Interventions
Cognitive Behavioral Therapy, Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Penicillin Allergy Testing in STD Clinics

NCT04620746
View directory record Official record
Conditions
Penicillin Allergy
Interventions
Penicillin Major Determinant (PrePen) Skin Testing, Direct Oral challenge
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
New Orleans, Louisiana • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional

Social Capital and Engagement in Care Among Young Black Men Who Have Sex With Men Living With HIV

NCT03664817
View directory record Official record
Conditions
HIV Infections
Interventions
social capital intervention, group-based health promotion intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2021 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Controlled Trial of Prenatal Coparenting Intervention (CoparentRCT)

NCT03097991
View directory record Official record
Conditions
Parenting
Interventions
Focused Coparenting Consultation
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
14 Years to 60 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 18, 2026, 11:29 AM EDT
Not listed Not applicable Interventional

Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock

NCT02972827
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
NICOM/FloTrac, Crystalloid Fluid Challenge
Device · Other
Lead sponsor
Santa Barbara Cottage Hospital
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2021 · Synced Oct 18, 2026, 11:29 AM EDT
Recruiting Phase 2 Interventional

Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis

NCT06686472
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
TL-925, Placebo
Drug
Lead sponsor
Telios Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics

NCT02459327
View directory record Official record
Conditions
Infant Behavior, Child Behavior, Parenting, Child Rearing, Depression, Personal Satisfaction, Behavioral Symptoms, Social Control, Informal
Interventions
Video Interaction Project, Family Check Up
Behavioral
Lead sponsor
New York University
Other
Eligibility
0 Years and older
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

OUR Stress/ Emotion Management for Black/African American Women With Hypertension

NCT04526145
View directory record Official record
Conditions
Stress, Psychological
Interventions
Stress and emotion management
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
40 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 18, 2026, 11:29 AM EDT
Not listed Phase 2 Interventional

A Study of TL-925 for the Treatment of Allergic Conjunctivitis

NCT06153342
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
TL-925, Placebo
Drug
Lead sponsor
Telios Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prehabilitation Using Aquatic Exercise

NCT02773745
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Aquatic Prehab
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Oct 18, 2026, 11:29 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments

NCT05644756
View directory record Official record
Conditions
Mental Health
Interventions
IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Irritation Potential of Omeza Collagen Matrix Using Modified HRIPT

NCT04510675
View directory record Official record
Conditions
Erythema, Sensitisation
Interventions
Test Article, Negative Control
Device · Other
Lead sponsor
Omeza, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 18, 2026, 11:29 AM EDT
Completed Phase 3 Interventional Results available

A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC)

NCT01551056
View directory record Official record
Conditions
Allergic Conjunctivitis
Interventions
AC-170 0.24%, AC-170 0%
Drug
Lead sponsor
Aciex Therapeutics, Inc.
Industry
Eligibility
10 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Oct 18, 2026, 11:29 AM EDT