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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Chewing Gum Clear all
Recruiting No phase listed Observational

Taking Measurements of a Gum Graft Site as it Heals

NCT07386457
View directory record Official record
Conditions
Gingival Recession
Interventions
Gingival graft surgery to treat gingival recession
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional

Development of a Tailored Smoking Cessation Program for Individuals With HIV Infection in Washington, D.C.

NCT04594109
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Tailored behavioral counseling, Standard of Care
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Maintaining Nonsmoking: Older Smokers - 1

NCT00086385
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Nicotine polacrilex, Bupropion
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2015 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Pediatric Taste Test Study of Cefdinir (Omnicef) Versus Amoxicillin Antibiotic Suspension Medications

NCT00644891
View directory record Official record
Conditions
Healthy
Interventions
cefdinir (Omnicef), amoxicillin
Drug
Lead sponsor
Abbott
Industry
Eligibility
4 Years to 8 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
3
States / cities
Scottsdale, Arizona • St. Petersburg, Florida • Miamiville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2008 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use

NCT03402243
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Menthol ban on cigarettes, Menthol ban on cigarettes and e-cigarettes, No menthol ban
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 17, 2026, 7:54 AM EDT
Not yet recruiting Phase 3 Interventional Accepts healthy volunteers

iCanQuit Smoking Cessation Among Hispanic Adults

NCT06811038
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
iCanQuit Smartphone App Smoking Cessation Program, Nicotine Gum, Nicotine Patch, Nicotine Lozenge, Survey Administration, Interview
Device · Drug · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
854 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 17, 2026, 7:54 AM EDT
Terminated Not applicable Interventional

Does Chewing Gum After Elective Laparoscopic Colectomy Surgery Decrease Ileus?

NCT00632801
View directory record Official record
Conditions
Ileus
Interventions
chewing gum
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 89 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Modern Nicotine Oral Product Abuse Liability

NCT06777784
View directory record Official record
Conditions
Smoking, Tobacco Use
Interventions
Product A, Product B, Product C, Product D, Product E, Product F, Product G, Product N
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Lexington, Kentucky • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum

NCT02664012
View directory record Official record
Conditions
Smoking
Interventions
Own Brand Menthol Cigarette, Electronic Menthol Cigarette #1, Electronic Menthol Cigarette #2, Electronic Menthol Cigarette #3, Leading U.S. Nicotine Gum
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 3, 2018 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fruit-based Chewing Gums for Improving Oral Health

NCT05755152
View directory record Official record
Conditions
Oral Health
Interventions
polyphenol-lecithin precipitate (PLP), control formulation
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 4 Interventional Results available

Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia

NCT02420015
View directory record Official record
Conditions
Schizophrenia, Cigarette Smoking
Interventions
Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling, Mobile Contingency Management, Stay Quit Coach, SMS text messaging
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional

Randomized Trial of a Gum Health Formulation

NCT03196648
View directory record Official record
Conditions
Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
Interventions
Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
Other
Lead sponsor
Glo Science, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 3 Interventional Results available

Phase 3 Clinical Study for the Treatment of Cold Sore

NCT00769314
View directory record Official record
Conditions
Herpes Labialis
Interventions
Acyclovir Lauriad, Placebo
Drug
Lead sponsor
Valerio Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
1,727 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
10
States / cities
Scottsdale, Arizona • Tucson, Arizona • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD190202: Study to Assess Elements of Abuse Liability for Two Electronic Nicotine Delivery Systems

NCT04094363
View directory record Official record
Conditions
Smoking, Tobacco Smoking, Tobacco Use
Interventions
Product A, Product B, Product C, Product D
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Knoxville, Tennessee • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chewing Gum for Weight Loss

NCT00971347
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Extra sugar-free chewing gum sticks, nutrition brochure
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 22, 2010 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pinhole Versus Tunnel for Soft Tissue Recession

NCT04513041
View directory record Official record
Conditions
Gingival Recession
Interventions
Pinhole surgical technique and tunnel technique in a split mouth design
Procedure
Lead sponsor
Mohanad Al-Sabbagh
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional

Mobile Contingency Management for Smoking Cessation in Returning US Veterans

NCT02513069
View directory record Official record
Conditions
Smoking, Veterans
Interventions
Nicotine gum, mobile contingency management, Telephone counseling, Nicotine patch, Nicotine lozenge, Smart phone, Carbon monoxide monitor
Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment

NCT04461288
View directory record Official record
Conditions
Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
Interventions
Social media-based education, counseling, and support, Nicotine replacement therapies (NRT), Gamification
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 4 Interventional Results available

A Smoking Cessation Intervention for Yale Dining Employees

NCT02562521
View directory record Official record
Conditions
Smoking Cessation
Interventions
Contingency management, Nicotine replacement therapy, Varenicline, Additional behavioral support
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2018 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional

The Effects of Nicotine Chewing Gum in Parkinson's Disease

NCT02452125
View directory record Official record
Conditions
Low Blood Pressure, Parkinsons Disease
Interventions
Nicotine gum
Dietary Supplement
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity

NCT06146712
View directory record Official record
Conditions
Sleep
Interventions
Asutra's 'Dream the night away' nighttime lotion
Other
Lead sponsor
Asutra
Industry
Eligibility
18 Years to 59 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2023 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement

NCT03126357
View directory record Official record
Conditions
Smoking
Interventions
Product A, Product B, Product C, Product D, Product E
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 17, 2026, 7:54 AM EDT
Recruiting Phase 1 Interventional

Effect of Insulin Lowering on Lipogenesis

NCT07403604
View directory record Official record
Conditions
Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State, Obesity
Interventions
Placebo, Diazoxide Oral Suspension, 2 mg per kg per dose, Deuterated water (2H2O/D2O), 70%, Insulin Suppression Test (IST)
Drug · Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 17, 2026, 7:54 AM EDT
Completed Phase 2 Interventional

Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients

NCT00060814
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Combined intervention
Other
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 17, 2026, 7:54 AM EDT