Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 9, 2026, 9:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Chiropractic Spinal Manipulation Clear all
Completed Not applicable Interventional

Individualized Chiropractic and Integrative Care for Low Back Pain

NCT00567333
View directory record Official record
Conditions
Sub-Acute and Chronic Low Back Pain
Interventions
Chiropractic care, Multidisciplinary, integrative care
Other
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Effects of Cervical Spine Manipulation On Postural Control

NCT00524654
View directory record Official record
Conditions
Posture
Interventions
HVLA chiropractic manipulation
Procedure
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2008 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 1Phase 2 Interventional

Cervicogenic Headache Dose-Response

NCT01530321
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Spinal Manipulation, Light Massage
Other
Lead sponsor
University of Western States
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomington, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional

Integrative Migraine Pain Alleviation Through Chiropractic Therapy

NCT03177616
View directory record Official record
Conditions
Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Migraine, Classic
Interventions
Chiropractic Treatment
Other
Lead sponsor
Harvard University Faculty of Medicine
Other
Eligibility
20 Years to 55 Years · Female only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Sep 9, 2026, 9:37 PM EDT
Not listed Not applicable Interventional

B Vitamin Supplementation to Chiropractic Management of Chronic LBP: Pilot Clinical Trial (VCLBP)

NCT06576739
View directory record Official record
Conditions
Recurrent Low Back Pain
Interventions
Spinal Manipulation
Procedure
Lead sponsor
University of Western States
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional

Z-Joint Changes in Low Back Pain Following Adjusting

NCT00284063
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Low back adjustment and MRI, MRI
Procedure
Lead sponsor
National University of Health Sciences
Other
Eligibility
21 Years to 69 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pregnancy-Related Low Back Pain and Complementary and Alternative Medicine (CAM) Treatment

NCT00937365
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise, Spinal Manipulation, Neuroemotional Technique (NET)
Behavioral · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 49 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

Collaborative Care for Older Adults With Back Pain (COCOA)

NCT01312233
View directory record Official record
Conditions
Low Back Pain
Interventions
Medical Care, Dual Care, Shared Care
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
65 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients

NCT00830596
View directory record Official record
Conditions
Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Sham Intervention
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years to 65 Years
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 9, 2026, 9:37 PM EDT
Enrolling by invitation No phase listed Observational

Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control

NCT06965920
View directory record Official record
Conditions
Spine Condition, Low Back Pain
Interventions
Not listed
Lead sponsor
Keiser University College of Chiropractic Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

Veterans Response to Dosage in Chiropractic Therapy

NCT04087291
View directory record Official record
Conditions
Low Back Pain, Patient Acceptance of Health Care, Veterans Health
Interventions
Chiropractic Care
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
766 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Los Angeles, California • West Haven, Connecticut • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 9, 2026, 9:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study

NCT03863769
View directory record Official record
Conditions
Spinal Stenosis Lumbar
Interventions
Lumbar Spinal Stenosis
Other
Lead sponsor
Parker University
Other
Eligibility
48 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Sep 9, 2026, 9:37 PM EDT
Terminated Not applicable Interventional

Post-concussion Syndrome and Chiropractic

NCT06151184
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Chiropractic adjustment
Procedure
Lead sponsor
Life University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Activator Manipulation Versus Manual Side Posture Manipulation in Patients With Low Back Pain

NCT00497861
View directory record Official record
Conditions
Back Pain
Interventions
Activator Methods Chiropractic Technique
Procedure
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 8, 2007 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional

Chiropractic and Self-care for Back-Related Leg Pain

NCT00494065
View directory record Official record
Conditions
Sub-acute and Chronic Back-related Leg Pain
Interventions
Home exercise, Chiropractic Spinal Manipulative Therapy + Home exercise
Other
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
21 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Davenport, Iowa • Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

Care Outcomes for Chiropractic Outpatient Veterans

NCT03254719
View directory record Official record
Conditions
Low Back Pain, PTSD, Depression, Anxiety
Interventions
Study assessments
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated May 17, 2020 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

The Effects of Chiropractic in a Population With High Central Adiposity

NCT06208163
View directory record Official record
Conditions
Abdominal Obesity
Interventions
Chiropractic
Procedure
Lead sponsor
Life University
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Functional Movement Scores Associated With Multimodal Chiropractic Care: a Pilot Feasibility Study

NCT05690568
View directory record Official record
Conditions
Chiropractic
Interventions
multimodal chiropractic care
Other
Lead sponsor
Cleveland University Kansas City
Other
Eligibility
21 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional

Manipulation, Exercise, and Self-Care for Neck Pain

NCT00269360
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic + Supervised Rehabilitative Exercise, Supervised Rehabilitative Exercise, Self-care education
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Not applicable Interventional Results available

Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis

NCT04972929
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Spinal Manipulation, Sham Spinal Manipulation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Low Back Pain

NCT00269321
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Manual treatment + home exercise (procedure+behavior), Supervised rehabilitative exercise+home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Sep 9, 2026, 9:37 PM EDT
Completed No phase listed Observational

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

NCT06653920
View directory record Official record
Conditions
Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions
Chiropractic, Exercise, Cryotherapy, Spinalator
Other · Device
Lead sponsor
Leach Chiropractic Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced Sep 9, 2026, 9:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Manipulation, Exercise, and Self-Care for Low Back Pain

NCT00269347
View directory record Official record
Conditions
Low Back Pain
Interventions
Chiropractic Spinal Manipulation, Exercise, Self-care
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 22, 2005 · Synced Sep 9, 2026, 9:37 PM EDT