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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Chloraprep Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride

NCT04207710
View directory record Official record
Conditions
Spray, Pain, Safety Issues
Interventions
Gebauer's Pain Ease Top Aerosol Mist Spray, Gebauer's Ethyl Chloride
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 3, 2024 · Synced Sep 2, 2026, 9:27 AM EDT
Withdrawn Not applicable Interventional

Prevention of Surgical Site Infection After Cesarean Delivery

NCT02027324
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Chlorhexidine-alcohol group, Povidone-Iodine Group
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Sep 2, 2026, 9:27 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cesarean Section Skin Prep - Does Skin Preparation Pattern Affect Skin Bacterial Burden

NCT04345562
View directory record Official record
Conditions
Cesarean Section Complications, Wound Infection
Interventions
Skin preparation patterns with ChloraPrep 2 x 26 mL single
Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 2, 2026, 9:27 AM EDT
Terminated Phase 4 Interventional

ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

NCT01184196
View directory record Official record
Conditions
Arthroplasty, Knee Replacement, Replacement, Total Knee, Total Knee Replacement
Interventions
Swab area with Betadine, Swab area with ChloraPrep
Drug
Lead sponsor
Central DuPage Hospital
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winfield, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Sep 2, 2026, 9:27 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

In-vivo Efficacy Study of Patient Preoperative Preps

NCT01968356
View directory record Official record
Conditions
Skin Flora Bacterial Reduction Post-product Application
Interventions
3M CHG/IPA Prep Colorless, 3M CHG/IPA Prep Tint, ChloraPrep, Saline
Drug
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 4 Interventional Results available

Pre-operative Alcohol Skin Solutions in Fractured Extremities

NCT03523962
View directory record Official record
Conditions
Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture, Pelvic Fracture
Interventions
DuraPrep, ChloraPrep
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
8,485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
24
States / cities
Irvine, California • Los Angeles, California • San Jose, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 3 Interventional Results available

Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections

NCT00290290
View directory record Official record
Conditions
Postoperative Wound Infection
Interventions
chlorhexidine-alcohol, Povidone-Iodine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
849 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
6
States / cities
West Roxbury, Massachusetts • Durham, North Carolina • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Compare Effect of Surgical Antiseptic Preparations on Incise Drape Adhesion to Skin

NCT01290978
View directory record Official record
Conditions
Healthy
Interventions
ChloraPrep, DuraPrep
Drug
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Broomall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 2, 2026, 9:27 AM EDT
Terminated Phase 2 Interventional Results available

Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor

NCT03423147
View directory record Official record
Conditions
Cesarean Section, Surgical Site Infection, Nosocomial Infection
Interventions
2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
Drug
Lead sponsor
Angela Bianco
Other
Eligibility
18 Years and older · Female only
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional

Multicenter Blood Culture Quality Improvement

NCT01413555
View directory record Official record
Conditions
Bacteremia
Interventions
Blood Culture QI Program
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
14,889 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional Results available

Retrospective Independent Safety Review of Closed Irrisept Study

NCT05359666
View directory record Official record
Conditions
Adverse Events
Interventions
Irrisept, Standard of Care
Device
Lead sponsor
Irrimax Corporation
Industry
Eligibility
Not listed
Enrollment
592 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
17
States / cities
Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Preoperative Skin Preparation Evaluation

NCT00636480
View directory record Official record
Conditions
Topical Antisepsis
Interventions
Chlorhexidine gluconate, ChloraPrep One Step, Sterile saline
Drug
Lead sponsor
C. R. Bard
Industry
Eligibility
16 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Pilot Evaluation of the Application Procedure on the Antimicrobial Effects of 2 Antiseptics

NCT00692484
View directory record Official record
Conditions
Healthy
Interventions
Chlorhexidine gluconate, Povidone iodine
Drug
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years to 90 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 3 Interventional Results available

Efficacy of TAP Block in Cesarean Section Patients

NCT03493828
View directory record Official record
Conditions
Pain Control
Interventions
TAP block using Bupivacaine 0.5%, TAP block using Bupivacaine 0.25%, TAP block using Normal Saline
Procedure
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation

NCT03861780
View directory record Official record
Conditions
Bacteria Microflora Reduction
Interventions
Project X 26ml, Project X 5.1ml, Prevantics Maxi Swabstick
Drug
Lead sponsor
Professional Disposables International, Inc.
Industry
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Topical Antimicrobial Effectiveness Testing

NCT01366417
View directory record Official record
Conditions
Antimicrobial Effectiveness
Interventions
ChloraPrep One-Step, 70% isopropyl alcohol
Drug
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Sterling, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 4 Interventional Results available

Visibility of Site Marking for Surgical Time Out With Two Different Skin Preparation Solutions

NCT00739583
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
CHG 2% w/v and IPA 70% v/v, Iodophor 0.7% and IPA 74% w/w
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional

Efficacy of Surgical Preparations in Lumbar Spine Surgery

NCT01105195
View directory record Official record
Conditions
Infection
Interventions
DuraPrep, ChloraPrep
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2010 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional

ULTRAPREP Used to Perform Skin Antisepsis Outside the Operating Room

NCT04600310
View directory record Official record
Conditions
Time Saved Performing Skin Antisepsis Process Outside the OR, Antisepsis of Skin Preparation Outside the OR
Interventions
ULTRAPREP, No Intervention
Device
Lead sponsor
Prep Tech, LLC
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Westlake, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)

NCT02296645
View directory record Official record
Conditions
Surgical Site Infection
Interventions
ZuraPrep, ChloraPrep
Drug
Lead sponsor
Zurex Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Sterling, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Skin Prep Study

NCT01472549
View directory record Official record
Conditions
Surgical Site Infections
Interventions
Iodine-alcohol, Chlorhexidine-alcohol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
1,147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 2, 2026, 9:27 AM EDT
Not listed Not applicable Interventional

Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With Hip OA Compared to Intra-articular Steroid Injections

NCT04329884
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
Cooled RFA treatment with COOLIEF* device, intra-articular corticosteroid injection
Procedure · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA

NCT02160574
View directory record Official record
Conditions
Surgical Site Infection
Interventions
ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline, ZuraPrep without IPA
Drug · Other
Lead sponsor
Zurex Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Sep 2, 2026, 9:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery

NCT01233050
View directory record Official record
Conditions
Colorectal Surgery
Interventions
2% Chlorhexidine Gluconate/70% Isopropyl Alcohol, Iodine Povacrylex/74% Isopropyl Alcohol
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
802 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 2, 2026, 9:27 AM EDT