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ClinicalTrials.gov public records Last synced Nov 10, 2026, 8:44 PM EST

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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Choline supplement Clear all

Conditions: Gestational Diabetes
Interventions: Choline supplement, Placebo; Dietary Supplement
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Pregnancy
Interventions: Choline; Dietary Supplement
Lead sponsor: Cornell University; Other
Eligibility: 21 Years to 40 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: Coronary Artery Disease, Diabetes, Metabolic Syndrome
Interventions: Eggs; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 35 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Storrs, Connecticut

Conditions: Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676, Male Infertility
Interventions: Betaine supplement; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Child Development, Cannabis Use
Interventions: Placebo, Choline; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
Interventions: Placebo, Citicoline, Pregnenolone; Drug · Dietary Supplement
Lead sponsor: Sherwood Brown, MD, PhD; Other
Eligibility: 18 Years to 70 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 3
States / cities: Miami, Florida • Dallas, Texas • Edinburg, Texas

Conditions: Alcohol Dependence
Interventions: Placebo, Citicoline; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Amphetamine Abuse, Amphetamine Dependence, Bipolar Disorder, Major Depressive Disorder
Interventions: Citicoline, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder, Prenatal Alcohol Exposure
Interventions: Choline, placebo supplementation consisting of vegetable glycerin (50% by volume) and deionized water; Dietary Supplement
Lead sponsor: San Diego State University; Other
Eligibility: 5 Years to 10 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: San Diego, California

Conditions: Cardiovascular Risk Factor
Interventions: Choline, Placebo; Dietary Supplement
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Mild Cognitive Impairment, Alzheimer Disease
Interventions: Citicoline Supplement, Placebo; Dietary Supplement · Other
Lead sponsor: Emory University; Other
Eligibility: 60 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Dietary Modification
Interventions: Carnitine, Choline, Antibiotics, Choline and Aspirin, Carnitine and Aspirin; Dietary Supplement · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2029
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Healthy
Interventions: Phosphatidylcholine, Betaine (588 mg qam and 412 mg qpm), Betaine (1000 mg BID); Dietary Supplement
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Healthy
Interventions: Placebo supplement, Citicoline and Omega-3 supplement, Omega-3 supplement; Dietary Supplement
Lead sponsor: Kyowa Hakko Bio Co., Ltd.; Industry
Eligibility: 55 Years and older
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypertriglyceridemia
Interventions: DHA-rich fish oil versus Phospholipid-rich fish oil; Dietary Supplement
Lead sponsor: Arctic Nutrition AS; Industry
Eligibility: 18 Years to 59 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain, Hypertension,Essential
Interventions: IV Vitamin Infused Therapy Treatment, Herbal medicine; Dietary Supplement · Drug
Lead sponsor: Faith A. Richardson; Other
Eligibility: 21 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Dover, Delaware

Conditions: Pregnancy, Lactation
Interventions: Choline Chloride; Dietary Supplement
Lead sponsor: Cornell University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: Cardiovascular Risk Factor
Interventions: Choline, Placebo; Dietary Supplement
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years to 79 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Cognitive Benefits
Interventions: Citicoline, Omega-3 Fatty Acids and Creatine; Drug
Lead sponsor: Deborah Yurgelun-Todd; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Cystic Fibrosis (CF)
Interventions: Common form supplementation, Uncommon nutrient supplementation; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Heart Failure
Interventions: R Drink; Dietary Supplement
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Metabolic Health, Elevated Liver Enzymes, Digestive Symptoms
Interventions: Plant-Based Liquid Supplement; Dietary Supplement
Lead sponsor: Biocol Labs; Industry
Eligibility: 40 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Cardiovascular Risk Factor
Interventions: Choline, Placebo; Dietary Supplement
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Healthy
Interventions: Phosphatidylcholine, Corn oil placebo; Dietary Supplement
Lead sponsor: The Gerber Foundation; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Search by objective public record fields.

Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus

Synergy Between Choline and DHA

Plasma TMAO and Choline Levels in Individuals With Metabolic Syndrome - Comparison Between Eggs and Choline Supplement.

Choline Dehydrogenase and Sperm Function: Effects of Betaine

Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Citicoline for Alcohol Dependence

A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence

Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders

Choline Supplementation and Cardiovascular Health

Improving Sleep and AD Biomarkers

CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease

Dietary Supplementation to Increase Serum Choline Levels

The Combination Effect of Citicoline and Omega-3

Bioavailability of EPA and DHA From Two Dietary Supplements

The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature

Effect of Maternal Choline Intake on Choline Status and Health Biomarkers During Pregnancy and Lactation

Choline and Cardiometabolic Health

Citicoline, Creatine, and Omega-3 Effects in Middle Age Women

Nutrition Supplement for Cystic Fibrosis

Dietary Supplementation in Heart Failure

A Clinical Trial to Evaluate the Effects of a Plant-Based Liquid Supplement on Metabolic Health and Overall Well-Being

Short Term Choline and Cardiovascular Health

Supplemental Choline and Brain Development in Humans