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Showing 1–6 of 6 matching trials from the live ClinicalTrials.gov search.
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Conditions
Nicotine Addiction, Cigarette Smoking
Interventions
Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds
Drug
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Recruiting Phase 2 Interventional Accepts healthy volunteers

Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes

NCT06614504
Conditions
Tobacco Use Disorder
Interventions
Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes
Other
Lead sponsor
University of Vermont
Other
Eligibility
21 Years and older
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Providence, Rhode Island • Burlington, Vermont
Completed Not applicable Interventional Accepts healthy volunteers Results available

Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace

NCT02951143
Conditions
Substance-Related Disorders
Interventions
SPECTRUM cigarettes, SPECTRUM cigarettes between
Drug
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Roanoke, Virginia
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder

NCT04092101
Conditions
Tobacco Use Disorder
Interventions
Cigarettes with varying nicotine content, E-Cigarettes
Other
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 70 Years
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Baltimore, Maryland • Burlington, Vermont
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age

NCT04092387
Conditions
Tobacco Use Disorder
Interventions
Varying the nicotine content of cigarettes, E-Cigarettes
Other
Lead sponsor
University of Vermont
Other
Eligibility
21 Years to 44 Years · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Baltimore, Maryland • Burlington, Vermont
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders

NCT04090879
Conditions
Tobacco Use Disorder
Interventions
Either normal nicotine content cigarettes (15.8mg/g) or reduced nicotine content cigarettes (0.4mg/g), E-Cigarettes
Other
Lead sponsor
Brown University
Other
Eligibility
18 Years to 70 Years
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Providence, Rhode Island • Burlington, Vermont