Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 48 matching trials from the live ClinicalTrials.gov search.
Conditions
Prediabetes
Interventions
herb and mineral combination product, Placebo
Dietary Supplement
Lead sponsor
NewChapter, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
6
States / cities
Chicago, Illinois • Lexington, Kentucky • Bingham Farms, Michigan + 3 more
Conditions
Diabetes, Pre-Diabetes
Interventions
water-soluble cinnamon extract (Cinnulin PF)
Drug
Lead sponsor
Mike O'Callaghan Military Hospital
Federal
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
4
States / cities
Travis Air Force Base, California • Eglin Air Force Base, Florida • Offutt Air Force Base, Nebraska + 1 more
Completed Phase 2 Interventional Results available

Supplements, Placebo, or Rosuvastatin Study

NCT04846231
Conditions
Hypercholesterolemia
Interventions
Fish Oil, Cinnamon, Garlique,Turmeric, Plant Sterol, Red Yeast Rice, Rosuvastatin, Placebo
Dietary Supplement · Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 75 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Bioavailability Study of Cinnamon in Healthy Subjects

NCT01847053
Conditions
Healthy Males
Interventions
cinnamon, Oatmeal
Other
Lead sponsor
McCormick and Company, Inc.
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Addison, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Cassia Cinnamon for Glucose Uptake in Young Women

NCT00951639
Conditions
Insulin Resistance, Impaired Glucose Tolerance, Prediabetes
Interventions
Cassia cinnamon, 50 minutes exercise, Cellulose Powder
Dietary Supplement · Procedure
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Waco, Texas
Conditions
Type 1 Diabetes Mellitus
Interventions
cinnamon
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
13 Years to 18 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Polycystic Ovary Syndrome, Insulin Resistance
Interventions
Cinnamon Supplementation, Placebo (wheat flour)
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effect of Spices on Vascular Health

NCT03064958
Conditions
Oxidative Stress
Interventions
Herbs and spices, High fat meal
Other
Lead sponsor
Penn State University
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Spice Consumption on Postprandial Vascular Function

NCT03063320
Conditions
Cardiovascular Risk Factor
Interventions
Spice blend
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Anosmia, Covid19, Ageusia, Hyposmia, Hypogeusia, SARS-CoV-2 Infection, COVID-19 Pandemic
Interventions
Smell Training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Sleep, Sleep Disturbance, Sleep Hygiene
Interventions
Beam Organics Dream Powder, Beam Organics Dream Powder Extra Strength, Placebo
Dietary Supplement
Lead sponsor
Beam
Industry
Eligibility
24 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Conditions
Smell Dysfunction, Olfactory Disorder, Long COVID
Interventions
Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO)
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses

NCT04686552
Conditions
Normal Weight, Overweight and Obesity
Interventions
cinnamon
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Insulin Resistance
Interventions
Food plan with cinnamon supplementation, Food plan without cinnamon supplementation
Dietary Supplement · Behavioral
Lead sponsor
Woman's
Other
Eligibility
Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Raisins Versus Alternative Snacks on Cardiovascular Risk Factors In Generally Healthy Subjects

NCT01260272
Conditions
Cardiovascular Risk Factors
Interventions
Alternative Snack Comparator, Raisins
Other
Lead sponsor
Louisville Metabolic and Atherosclerosis Research Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Obesity & Overweight, Muscle Mass and Strength, Muscle Function
Interventions
Whey Protein Supplementation, Maltodextrin Placebo Capsules, Mixed Spice Capsules
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Spices, Inflammation and Vascular Response in Humans

NCT03926442
Conditions
Healthy
Interventions
Italian Herb meal, Cinnamon Meal, Pumpkin Spice meal, Placebo meal
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Smoking Cessation, Harm Reduction
Interventions
Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product, BIDI e-cigarette, on!
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)

NCT00954902
Conditions
Cardiovascular, Psychological Stress
Interventions
High Antioxidant Spice Blend, Trier Psychological Stressor, Placebo antioxidant concentrate
Dietary Supplement · Behavioral · Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
PreDiabetes, Blood Glucose, High
Interventions
Cinnamon, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Effect of Funk It Cycle Bites on PMS

NCT05900024
Conditions
Premenstrual Syndrome
Interventions
Funk It Cycle Bites
Other
Lead sponsor
Funk It Wellness
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Santa Monica, California
Conditions
Hunger, Weight Change
Interventions
Leptin Balance Formula
Dietary Supplement
Lead sponsor
Efforia, Inc
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Chronic Kidney Diseases, Overweight and Obesity
Interventions
Honey Spice Group
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

RCT of a Polyherbal Dietary Supplement for Prediabetes

NCT03388762
Conditions
Prediabetic State
Interventions
GlucoSupreme™ Herbal, Placebo
Dietary Supplement · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Baltimore, Maryland • Cincinnati, Ohio