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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:13 AM EDT

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Showing 25–44 of 44 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Circadian rhythm assessment Clear all
Completed Phase 1 Interventional Results available

Modeling Mood Course to Detect Markers for Effective Adaptive Interventions- Aim 3

NCT04098497
View directory record Official record
Conditions
Bipolar Disorder, Psychosocial Intervention
Interventions
Mobile intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 6, 2026, 10:13 AM EDT
Withdrawn No phase listed Observational

Circadian RA Study in Rheumatoid Arthritis Subjects

NCT03178955
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Etanercept
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 6, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Diurnal Variation in Tear Osmolarity

NCT01321424
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Not listed
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
6
States / cities
Fairfield, Connecticut • Lynbrook, New York • Manhasset, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Light and Exercise on Human Circadian Rhythms and Performance

NCT02747719
View directory record Official record
Conditions
Circadian Rhythm
Interventions
Light and exercise
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 6, 2026, 10:13 AM EDT
Active, not recruiting Not applicable Interventional

Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon Carcinogenesis

NCT03955510
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Right time eating, Delayed time eating, Sigmoidoscopy, Optional 24h circadian assessment in the Biological Rhythms lab, Alcohol
Other · Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 6, 2026, 10:13 AM EDT
Recruiting Phase 3 Interventional

Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

NCT06568367
View directory record Official record
Conditions
Excessive Sleepiness, Shift-work Disorder
Interventions
Solriamfetol 150 mg, Solriamfetol 300 mg, Placebo
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
44
States / cities
Auburn, Alabama • Cullman, Alabama • Chandler, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Heroes Study

NCT03533023
View directory record Official record
Conditions
Shift Workers' Health, Time Restricted Eating, Fasting
Interventions
Time Restricted Eating + Standard of Care, Standard of Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2011 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Time Restricted EATing (TREAT) Pilot Study

NCT03956290
View directory record Official record
Conditions
Overweight and Obesity, Pre Diabetes
Interventions
TREAT pilot intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
45 Years to 73 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Oct 6, 2026, 10:13 AM EDT
Terminated Not applicable Interventional Results available

Melatonin for Circadian Sleep Disorders in the Blind

NCT00911053
View directory record Official record
Conditions
Insomnia, Blindness, Daytime Sleepiness
Interventions
Melatonin, Regular Sleep Schedule, Light
Drug · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers

NCT00492011
View directory record Official record
Conditions
Circadian Dysregulation
Interventions
Ramelteon, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 50 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
4
States / cities
Miami, Florida • Pembroke Pines, Florida • Honolulu, Hawaii + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2012 · Synced Oct 6, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional

The Acute T-Rex (Timing of Resistance Exercise) Study

NCT06366399
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Insulin Resistance, Glucose Intolerance, Sleep Disturbance, Overweight or Obesity, Insulin Sensitivity
Interventions
Resistance Exercise Timing
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
50 Years to 74 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 6, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

NCT06471374
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome, Delayed Sleep Phase
Interventions
Circadian rhythm assessment, Light sensitivity assessment
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
16 Years to 40 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boulder, Colorado • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 6, 2026, 10:13 AM EDT
Recruiting No phase listed Observational

Patient Registry of Blind Subjects With Sleep-related Problems

NCT01195558
View directory record Official record
Conditions
Sleep-wake Disorder in Blind Individuals
Interventions
Data collection on blindness and sleep problems
Other
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 6, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health Behaviors and Time-of-Day: Older Adult Cognitive Function

NCT02300272
View directory record Official record
Conditions
Alteration of Cognitive Function, Ageing
Interventions
Polysomnograph, Actiwatch
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 6, 2026, 10:13 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Daytime vs. Delayed Eating Among Obese Individuals

NCT03354169
View directory record Official record
Conditions
Obesity
Interventions
Eating Condition, No Intervention; withdrawn before randomization
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Individually Tailored Lighting System to Improve Sleep in Older Adults

NCT01855126
View directory record Official record
Conditions
Sleep Disturbances
Interventions
Blue light, Red light
Other
Lead sponsor
Rensselaer Polytechnic Institute
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 6, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CircaHealth Development and Evaluation

NCT03835572
View directory record Official record
Conditions
Health Behavior, Health Knowledge, Attitudes, Practice, Circadian Rhythm
Interventions
CircaHealth: a course on circadian rhythms and health, Sleep hygiene materials
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 6, 2026, 10:13 AM EDT
Completed No phase listed Observational

Study of Sleep and Delirium in the Intensive Care Unit (ICU)

NCT01280097
View directory record Official record
Conditions
Delirium, Sleep Disorders, Circadian Rhythm
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Oct 6, 2026, 10:13 AM EDT