Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:10 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 208 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Circadin Clear all

Conditions: Sleep
Interventions: Proprietary Blend of Botanical Extracts, Melatonin; Dietary Supplement
Lead sponsor: Nutraceuticals Research Institute; Other
Eligibility: 35 Years to 55 Years · Female only
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Huntsville, Alabama

Conditions: Musculoskeletal Diseases
Interventions: Muscle Strength Training; Device
Lead sponsor: Duquesne University; Other
Eligibility: 30 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sleep, Burns
Interventions: Not listed
Lead sponsor: Shriners Hospitals for Children; Other
Eligibility: 5 Years to 18 Years
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Seasonal Affective Disorder, Healthy
Interventions: Propranolol; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Depression During the Menopausal Transition, Menopausal Depression
Interventions: Phase Advanced Intervention (PAI), Phase Delay Intervention (PDI); Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 45 Years to 75 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep, Sleep Hygiene
Interventions: Timed evening technology and digital media use (tablet use), no technology and digital media use (screen media use); Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 48 Months to 59 Months
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: COVID-19
Interventions: Melatonin, Placebo; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Obstructive Sleep Apnea
Interventions: Melatonin, Placebo; Dietary Supplement · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep
Interventions: Plant-based melatonin, Melatonin, Placebo; Dietary Supplement
Lead sponsor: Nutraland USA, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 244 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Sleep Disturbance, Trauma
Interventions: Melatonin 5mg and Sleep Education, Placebo; Dietary Supplement · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Migraine
Interventions: Melatonin, Placebo oral capsule; Drug
Lead sponsor: Amy Gelfand; Other
Eligibility: 10 Years to 17 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Los Angeles, California • San Francisco, California

Conditions: Blindness
Interventions: Melatonin; Biological
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 1 Year to 20 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2015
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Altitude Hypoxia, Ventilation, Sleep, Oxidative Stress, Neurocognitive Dysfunction
Interventions: Melatonin, Hypoxia; Dietary Supplement · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Osteo Arthritis Knee
Interventions: Melatonin 5 mg, Placebo; Drug · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 95 Years
Enrollment: 294 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Pregnancy Related, Labor; Poor, Uterine Contractions Weak
Interventions: Room light/light bulb; Device
Lead sponsor: Michigan State University; Other
Eligibility: 18 Years to 42 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: East Lansing, Michigan

Conditions: Pregnant Women
Interventions: Melatonin, Placebo; Dietary Supplement
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Delirium
Interventions: Melatonin, Placebo; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 65 Years and older
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Melatonin
Interventions: Light - standard, Light - alternate; Device
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 18 Years to 35 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Tobacco Use Disorder
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Acute Kidney Injury, Adverse Drug Event
Interventions: Melatonin, Placebo Capsule; Drug · Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 75 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: New Brunswick, New Jersey • Somerville, New Jersey

Conditions: Preterm Contractions
Interventions: Ocular light; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Circadian Rhythm Sleep Disorder, Jet Lag Type
Interventions: Bright Light, Bright Light + Exercise + Melatonin, Control; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 45 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Arthroplasty, Replacement, Knee, Sleep Initiation and Maintenance Disorders
Interventions: Melatonin 5 mg, Placebo (Vitamin C); Dietary Supplement
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years and older
Enrollment: 176 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Biological Clock Dysfunction, Optic Nerve Hypoplasia
Interventions: Melatonin, Placebo Comparator; Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 2 Years to 10 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality

Strength Training Effects on Musculoskeletal Health

Circadian Rhythm of Melatonin in Burns

Clinical Trial of Propranolol for Seasonal Affective Disorder

Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction

The Goodnight Screen Media Study

Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19

The Effect of Melatonin on Sleep and Ventilatory Control in Obstructive Sleep Apnea

Somato® (Phytomelatonin) Versus Synthetic Melatonin and Placebo on Sleep Quality

Treatment for Sleep Disturbance in Orthopaedic Trauma Patients

Melatonin for Adolescent Migraine Prevention Study

Young Blind Child Melatonin Treatment Study

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

Melatonin Use After Primary Total Joint Arthroplasty

Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy

Testing Effects of Melatonin on Uterine Contractions in Women

Prevention of Delirium in Inpatients Utilizing Melatonin

Color-dependent Melatonin Suppression

Effect of Ramelteon on Smoking Abstinence

Melatonin for Prevention of Kidney Injury

Uterine Contractions Under Blue Light

Facilitating Adjustment to Simulated Jet Lag

TKA Melatonin and Sleep Quality

Biological Clock Dysfunction in Optic Nerve Hypoplasia