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ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:19 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 208 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Circadin Clear all

Conditions: Smith Magenis Syndrome
Interventions: Not listed
Lead sponsor: Vanda Pharmaceuticals; Industry
Eligibility: 6 Years to 50 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Quality
Interventions: Filtered Eyewear, Unfiltered Eyewear, No Filters; Device · Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Menands, New York

Conditions: Seasonal Affective Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1995 – 2000
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Insomnia, Depression
Interventions: Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU); Behavioral · Other
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Alcohol Dependence, Insomnia
Interventions: Placebo dispensed to subject., Gabapentin dispensed to subject.; Drug
Lead sponsor: Dr. Kirk Brower; Other
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Bronchitis
Interventions: Ivermectin; Drug
Lead sponsor: Patrick Robinson; Other
Eligibility: 12 Years to 110 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Antonio, Florida

Conditions: Stroke, Acute, Ischemic Stroke
Interventions: Melatonin; Dietary Supplement
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Hypertension
Interventions: Melatonin, Placebo; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Perimenopause, Hypertension
Interventions: Terry Naturally® melatonin 5mg SR, Placebo; Dietary Supplement
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years to 55 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: Sleep Intervention, Melatonin; Behavioral · Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 6 Years to 12 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
Interventions: Melatonin tablet 3 mg once daily, Thiamine; Dietary Supplement
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Non-24 Hour Sleep-Wake Disorder, Blindness
Interventions: melatonin (Circadin), placebo; Drug
Lead sponsor: Neurim Pharmaceuticals Ltd.; Industry
Eligibility: 20 Years to 80 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder
Interventions: clozapine, risperidone; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 524 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 5
States / cities: Hartford, Connecticut • Athens, Georgia • Chicago, Illinois + 2 more

Conditions: Sleep
Interventions: Asutra's 'Dream the night away' nighttime lotion; Other
Lead sponsor: Asutra; Industry
Eligibility: 18 Years to 59 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: COVID-19
Interventions: Melatonin, Placebo (Methylcellulose) capsule; Drug · Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Healthy Adult Subjects, Healthy Elderly Subjects
Interventions: BIIB118, Melatonin; Drug
Lead sponsor: Biogen; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 97 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: South Miami, Florida

Conditions: Covid19, SARS-CoV Infection
Interventions: Vitamin C, melatonin, Placebo, Symptom Survey; Dietary Supplement · Other
Lead sponsor: Lancaster General Hospital; Other
Eligibility: 50 Years and older
Enrollment: 122 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: 3 mg Melatonin, 5 mg Melatonin; Drug
Lead sponsor: Providence Health & Services; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Gastrointestinal Cancer, Lung Cancer
Interventions: Melatonin, Placebo; Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Houston, Texas

Conditions: Insomnia, Asthma
Interventions: Ramelteon; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Low Back Pain
Interventions: Bright light; Device
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Brain Cancer
Interventions: Questionnaire; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anesthesia
Interventions: Sleep Mask; Other
Lead sponsor: Englewood Hospital and Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Englewood, New Jersey

Conditions: Delayed Sleep Phase Syndrome
Interventions: Melatonin 0.5 MG, Dim Light Melatonin Onset (salivary); Drug · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

Observational Study to Investigate the Melatonin and Cortisol Circadian Rhythms of Individuals With Smith-Magenis Syndrome (SMS)

Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1

Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder

Sleep to Reduce Incident Depression Effectively in Peripartum

Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence

Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19

Melatonin in Acute Stroke

Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study

Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial

Improving Sleep and Daytime Functioning Among Children Diagnosed With Attention Deficit Hyperactivity Disorder (ADHD)

Affect of Melatonin on Sleep and Cognition in Cirrhosis

Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects

CLOZAPINE Response in Biotype-1

A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity

Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

The Effect of Melatonin and Vitamin C on COVID-19

Melatonin in Patients With Multiple Sclerosis (MS).

Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients

Ramelteon for Insomnia Comorbid With Asthma

Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans

Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients

Does Melatonin Affect Anesthetic MAC (Minimum Alveolar Concentration)?

The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder