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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions

NCT01791517
Conditions
Contact Lens Solutions
Interventions
Solution 1 (Test), Solution 2 (Test), Solution 3 (Test), Solution 4 (Control)
Other
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Conditions
Keratoconus
Interventions
KeraSoft IC Soft Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, New York
Conditions
Refractive Errors, Ametropia
Interventions
Lehfilcon A contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Hydrogen peroxide-based cleaning and disinfecting solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Conditions
Refractive Errors
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
5
States / cities
Maitland, Florida • Medina, Minnesota • Granville, Ohio + 2 more
Conditions
Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
11
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 8 more
Conditions
Myopia
Interventions
O2Optix contact lens, Proclear contact lens, ReNu MultiPlus Multi-Purpose Solution, Clear Care Cleaning and Disinfecting Solution
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
473 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
25
States / cities
North Little Rock, Arkansas • Campbell, California • Cupertino, California + 22 more
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
14
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Conditions
Contact Lens Solution
Interventions
Opti-Free contact lens solution, ReNu Multiplus contact lens solution, Clear Care contact lens solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Virginia Beach, Virginia
Completed Not applicable Interventional Results available

Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens

NCT04207749
Conditions
Refractive Errors, Myopia, Hyperopia
Interventions
LID015385 contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
18
States / cities
Glendale, Arizona • Brentwood, California • Irvine, California + 15 more
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
8
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Conditions
Refractive Errors, Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Myopia
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
5
States / cities
Maitland, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Conditions
Refractive Ametropia
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
15
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Conditions
Conjunctival Staining
Interventions
Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

NCT01250925
Conditions
Myopia, Refractive Error
Interventions
ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Iowa City, Iowa • Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of A New Contact Lens Cleaning and Disinfecting Solution

NCT01318577
Conditions
Vision Disorders
Interventions
Investigational Cleaning & Disinfecting Solution, Clear Care Solution
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Conditions
Refractive Errors, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Completed Not applicable Interventional Results available

Clinical Assessment of a HYDRAGLYDE® Regimen

NCT03026257
Conditions
Refractive Errors, Myopia, Hypermetropia
Interventions
Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent, Hydrogen peroxide-based contact lens solution with added wetting agent, Senofilcon C contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Habitual Multi-Purpose Solution (HMPS)
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types

NCT03466060
Conditions
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Interventions
Opti-Free : RevitaLens / Clear Care : RevitaLens, Opti-Free : RevitaLens / RevitaLens : Clear Care, Clear Care : RevitaLens/ Opti-Free : RevitaLens, Clear Care : RevitaLens / RevitaLens : Opti-Free, RevitaLens : Clear Care/ Opti-Free : RevitaLens, RevitaLens : Clear Care / RevitaLens : Opti-Free, RevitaLens : Opti-Free / Clear Care : RevitaLens, RevitaLens : Opit-Free / RevitaLens : Clear Care
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
5
States / cities
Anaheim, California • Berkeley, California • Jacksonville, Florida + 2 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Daily Wear Corneal Infiltrative Event Study

NCT00937105
Conditions
Myopia, Hyperopia, Corneal Infiltrative Events
Interventions
lotrafilcon A contact lenses, Renu Multiplus, Clear Care
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
15 Years and older
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio